anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Antikörper

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. Zusätzlich bieten wir Ihnen DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DCLRE1B 64858 Q9H816
DCLRE1B 310745 Q4KLY6
DCLRE1B 140917 Q8C7W7
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Top anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Antikörper auf antikoerper-online.de

Showing 10 out of 30 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB DCLRE1B Antibody (Center)(ABIN651618) western blot analysis in mouse kidney tissue lysates (35 µg/lane). This demonstrates the DCLRE1B antibody detected DCLRE1B protein (arrow). DCLRE1B Antibody (Center) (ABIN651618) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of DCLRE1B expression in HOS (A) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert FACS, IHC, WB HEK293T cells transfected with either RC205744 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DCLRE1B antibody (ABIN2454181), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCLRE1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DCLRE1B. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$482.90
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the detected DCLRE1B protein (arrow). DCLRE1B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Maus Unkonjugiert FACS, IHC (p), WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of THP-1 cells, using DCLRE1B antibody. 100 μL Anmelden zum Anzeigen 16 Days
$476.15
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$793.83
Details
Human Maus Unkonjugiert FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: DCLRE1B Antibody (2B7) [NBP2-03563] Staining of paraffin-embedded Human endometrium tissue using anti-DCLRE1B mouse monoclonal antibody. Western Blot: DCLRE1B Antibody (2B7) [NBP2-03563] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCLRE1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DCLRE1B. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$556.31
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
Details

DCLRE1B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)


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Am meisten referenzierte anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Antikörper

  1. Human Polyclonal DCLRE1B Primary Antibody für IHC (p), WB - ABIN651618 : Bae, Mukhopadhyay, Liu, Zhang, Tan, Akhter, Liu, Shen, Li, Legerski: Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links. in Oncogene 2008 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Interaktionspartner

Human DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Interaktionspartner

  1. Different charge distributions along the DNA binding groove may account for the drastic difference in processivity and DNA digestion efficiency, including that of damaged substrates, between SNM1A (zeige DCLRE1A Antikörper) and SNM1B.

  2. The SNM1B/APOLLO DNA nuclease (zeige DCLRE1C Antikörper) functions in resolution of replication stress and maintenance of common fragile site stability.

  3. the N-terminal region of Snm1B forms a complex containing PSF2 (zeige TAP2 Antikörper) and Mus81 (zeige MUS81 Antikörper), while the C-terminal region is important for PSF2 (zeige TAP2 Antikörper)-mediated chromatin association.

  4. The nuclease (zeige DCLRE1C Antikörper) hSNM1B/Apollo is linked to the Fanconi anemia (zeige PALB2 Antikörper) pathway via its interaction with FANCP/SLX4 (zeige BTBD12 Antikörper).

  5. differences in the substrate selectivities of SNM1A (zeige DCLRE1A Antikörper) and SNM1B are likely to be relevant to their in vivo roles

  6. SNM1B functions epistatically to the central Fanconi anemia (zeige PALB2 Antikörper) factor, FANCD2 (zeige FANCD2 Antikörper), in cellular survival after interstrand crosslinks damage and homology-directed repair of DNA double-strand breaks

  7. TRF2 (zeige TERF2 Antikörper), which binds preferentially to positively supercoiled DNA substrates, together with Apollo, negatively regulates the amount of TOP1 (zeige TOP1 Antikörper), TOP2alpha, and TOP2beta (zeige TOP2B Antikörper) at telomeres.

  8. siRNA knockdown of hSNM1B rendered cells sensitive to ionizing radiation, suggesting the possibility of hSNM1B involvement in homologous recombination repair of double-strand breaks arising as intermediates of ICL repair

  9. the C terminus of Snm1B was shown to interact with the TRF (zeige IL5 Antikörper) homology domain of TRF2 (zeige TERF2 Antikörper) indicating that Snm1B is likely recruited to the telomere via interaction with the double-stranded telomere-binding protein TRF2 (zeige TERF2 Antikörper)

  10. SNM1B (Apollo) protein exhibits a 5'-to-3' DNA exonuclease (zeige EXO1 Antikörper) activity and functions together with TRF2 (zeige TERF2 Antikörper) to protect telomeres from damage and fusion.

Mouse (Murine) DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Interaktionspartner

  1. Study documents the combinatorial action of Apollo, POT1b, CST (zeige CORT Antikörper), and the 5' exonuclease (zeige EXO1 Antikörper) Exo1 (zeige EXO1 Antikörper) in postreplicative telomere end processing in mouse cells, clarifying the mechanism by which the telomeric 3' overhang is generated and modulated.

  2. The telomeric protein (zeige SYCE1 Antikörper) SNM1B/Apollo is required for normal cell proliferation and embryonic development

  3. TRF2 (zeige TERF2 Antikörper)-bound Apollo functions at replicating telomeres, promoting the maintenance of the telomeric overhang, repressing S phase-specific ATM (zeige ATM Antikörper) signaling, and protecting leading-end telomeres from fusion.

  4. Apollo null mouse embryo fibroblasts exhibit an increased incidence of G2 chromatid-type fusions involving telomeres created by leading-strand DNA synthesis, reflective of a failure to protect these telomeres after DNA replication.

DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Antigen-Profil

Protein Überblick

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000

Genbezeichner und Symbole assoziert mit DCLRE1B

  • DNA cross-link repair 1B (DCLRE1B) Antikörper
  • DNA cross-link repair 1B (Dclre1b) Antikörper
  • DNA cross-link repair 1B (dclre1b) Antikörper
  • AI452214 Antikörper
  • Apollo Antikörper
  • im:6894074 Antikörper
  • mSNM1B Antikörper
  • SNM1B Antikörper
  • SNMIB Antikörper
  • zgc:154089 Antikörper

Bezeichner auf Proteinebene für DCLRE1B

5' exonuclease Apollo , DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) , PSO2 homolog , SNM1 homolog B , DNA cross-link repair 1B protein

GENE ID SPEZIES
64858 Homo sapiens
428269 Gallus gallus
310745 Rattus norvegicus
768137 Danio rerio
140917 Mus musculus
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