DNA (Cytosine-5-)-Methyltransferase 3 beta Proteine (DNMT3B)

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation.

alle Proteine anzeigen Gen GeneID UniProt
Human DNMT3B DNMT3B 1789 Q9UBC3
Ratte DNMT3B DNMT3B 444985  
Maus DNMT3B DNMT3B 13436 O88509
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Top DNMT3B Proteine auf antikoerper-online.de

Showing 8 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Maus T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage

Am meisten referenzierte DNMT3B Proteine

  1. Human DNMT3B Protein expressed in HEK-293 Cells - ABIN2719618 : Cree, Fredericks, Miller, Pearce, Filichev, Fee, Kennedy: DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro. in FEBS letters 2016 (PubMed)

Weitere Proteine zu DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartnern

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation (zeige HELLS Proteine) content are rather a function of time, and not a genetic component.

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.

  2. The expression levels of DNMT3a (zeige DNMT3A Proteine) and DNMT3b were associated with several beef quality traits.

Human DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Our study expands the mutation spectrum in ICF syndrome and supports that DNMT3B and ZBTB24 (zeige ZBTB24 Proteine) are the most common disease genes

  2. Alternative splice variant of DNMT3B is associated with leukemia.

  3. these results provided a plausible link between the observed reduction of miR (zeige MLXIP Proteine)-26a and MEG3 (zeige FAM129B Proteine) in HCCs (zeige HCCS Proteine). Together, the present study added miR (zeige MLXIP Proteine)-26a/DNMT3B/MEG3 (zeige FAM129B Proteine) axis to the complex mechanisms of HCC (zeige FAM126A Proteine) development.

  4. Results show that DNMT1 (zeige DNMT1 Proteine) mRNA levels were significantly higher in alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma tumors compared to normal skeletal muscle. Thse data indicate that altered expression of DNMT3B plays a key role in embryonal rhabdomyosarcoma development since its silencing is able to reverse cell cancer phenotype by rescuing myogenic program.

  5. The present study shows that DNMT3B rs2424913 promotor polymorphism represents a genetic risk factor that may play an important role in understanding the pathogenesis of chronic immune thrombocytopenia.

  6. LMP1-mediated NF-kappaB can up-regulate DNMT3b transcription, thereby leading to relatively higher methylation intensity at PTEN CpG islands, and ultimately silencing major tumor suppressor PTEN

  7. DNMT1 (zeige DNMT1 Proteine), DNMT3A (zeige DNMT3A Proteine), and DNMT3B were overexpressed in 36.9, 26, and 23 % of the OSCC patients, respectively. DNMT1 (zeige DNMT1 Proteine) overexpression was significantly associated with the overall survival, p = 0.029, and relapse-free survival of OSCC patients, p = 0.003. Patients with DNMT1 (zeige DNMT1 Proteine) overexpression, as an independent prognostic factor, had a 2.385 times higher risk to relapse than those with lower expression. The DNMT1 (zeige DNMT1 Proteine) A201G gene polymorphi

  8. report the first crystal structure of the DNMT3B PWWP domain-H3K36me3 complex.

  9. Results continue to establish ANG (zeige ANG Proteine) as an oncoprotein and further reveal that ANG (zeige ANG Proteine) contributes to oncogenesis by the activation of MMP2 (zeige MMP2 Proteine) through modulation of DNMT3b functions.

  10. found association between DNMT3B rs2424913 in T allele carriers with Parkinson's disease

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. The epiblast expressed epithelial markers, MUC1 (zeige MUC1 Proteine) and E-CADHERIN (zeige CDH1 Proteine), and the pluripotency markers, DNMT3B and CRIPTO (zeige TDGF1 Proteine).

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1 (zeige DNMT1 Proteine), DNMT3A (zeige DNMT3A Proteine), and DNMT3B proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.

  2. Altogether, the authors demonstrate that Dnmt3a (zeige DNMT3A Proteine) and Dnmt3b protect the epidermis from tumorigenesis and that squamous carcinomas are sensitive to inhibition of PPAR-gamma (zeige PPARG Proteine).

  3. a new paradigm of transcriptional regulation critical for cardiac development and maturation that is controlled by the interaction of REST, DNMT3B and non-CpG methylation.

  4. Together, this study described the regulation of Chk2 (zeige CHEK2 Proteine) expression through promoter methylation by Dnmt3b and also presented a novel role of Chk2 (zeige CHEK2 Proteine) during neuronal differentiation, which is independent of its previously known function in DNA damage response.

  5. in mouse embryonic stem cells, Dnmt3b-dependent intragenic DNA methylation protects the gene body from spurious RNA polymerase II entry and cryptic transcription initiation

  6. three DNA methyltransferases, Dnmt1 (zeige DNMT1 Proteine), Dnmt3a (zeige DNMT3A Proteine), and Dnmt3b, have been identified. Dnmt3a (zeige DNMT3A Proteine) and Dnmt3b are responsible for establishing DNA methylation (zeige HELLS Proteine) patterns produced through their de novo-type DNA methylation (zeige HELLS Proteine) activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l (zeige TRDMT1 Proteine)), which is a member of the Dnmt3 family but does not possess DNA methylation (zeige HELLS Proteine)

  7. While lens epithelial cell survival requires DNMT1 (zeige DNMT1 Proteine), morphologically normal lenses develop in the absence of both DNMT3A (zeige DNMT3A Proteine) and DNMT3B.

  8. Mechanical stimulation regulates osteoblastic genes expression via direct regulation of Dnmt3b.

  9. a miR (zeige MLXIP Proteine)-125b-DNMT3b-p53 (zeige TP53 Proteine) signal pathway may exist in the vascular smooth muscle cells proliferation induced by homocysteine.

  10. miR-29a mimic transfection lowered collagen 1alpha1, DNMT1, DNMT3b and SET1A expression in hepatic stellate cells.

Zebrafish DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. dnmt7 specifically methylates no tail gene in the genome

DNMT3B Protein Überblick

Protein Überblick

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Genbezeichner und Symbole assoziert mit DNMT3B

  • DNA methyltransferase 3 beta (DNMT3B)
  • DNA methyltransferase 3 beta (Dnmt3b)
  • DNA methyltransferase 3 beta (dnmt3b)
  • DNA methyltransferase 3B (Dnmt3b)
  • DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a (dnmt3ba)
  • cb91 Protein
  • DNMT3B Protein
  • dnmt3bl Protein
  • dnmt7 Protein
  • ICF Protein
  • ICF1 Protein
  • LOC100218113 Protein
  • M.HsaIIIB Protein
  • MmuIIIB Protein
  • sb:cb91 Protein
  • wu:fb16h07 Protein

Bezeichner auf Proteinebene für DNMT3B

DNA cytosine-5 methyltransferase 3 beta , DNA (cytosine-5)-methyltransferase 3B , DNA methyltransferase HsaIIIB , DNA (cytosine-5-)-methyltransferase 3 beta , DNA MTase HsaIIIB , DNA methyltransferase 3B , DNA (cytosine-5)-methyltransferase 3B-like , DNA MTase MmuIIIB , DNA methyltransferase MmuIIIB , DNA (cytosine-5-)-methyltransferase 3 beta, like , DNA (cytosine-5-)-methyltransferase 7 , fb16h07 , LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B

458174 Pan troglodytes
419287 Gallus gallus
711553 Macaca mulatta
100053900 Equus caballus
353354 Bos taurus
100218113 Taeniopygia guttata
1789 Homo sapiens
444985 Rattus norvegicus
100302109 Sus scrofa
100412936 Callithrix jacchus
100459992 Pongo abelii
100466728 Ailuropoda melanoleuca
100598378 Nomascus leucogenys
100528060 Anolis carolinensis
13436 Mus musculus
321084 Danio rerio
100731772 Cavia porcellus
100685634 Canis lupus familiaris
100349823 Oryctolagus cuniculus
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