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Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (By similarity). Zusätzlich bieten wir Ihnen DIM1 Dimethyladenosine Transferase 1 Homolog (S. Cerevisiae) Proteine (11) und und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal DIMT1 Primary Antibody für ELISA, WB - ABIN544723
Stanchi, Bertocco, Toppo, Dioguardi, Simionati, Cannata, Zimbello, Lanfranchi, Valle: Characterization of 16 novel human genes showing high similarity to yeast sequences. in Yeast (Chichester, England) 2001
DIMT1 is overexpressed in gastric carcinoma and is significantly correlated with poor prognosis.
Studies show that miroRNA miR-210 acts as a tumor suppressor in hypoxic conditions by downregulating the 18S rRNA base methyltransferase (DIMT1)-interferon regulatory factor 4 (IRF4) axis.
DIMT1L and WBSCR22-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity.
Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection by activating STMN1 and DIMT1.
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (By similarity).
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
, probable dimethyladenosine transferase
, dimethyladenosine transferase
, 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase
, 18S rRNA dimethylase
, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase
, probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase
, probable 18S rRNA dimethylase
, probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase
, DIM1 dimethyladenosine transferase 1 homolog