Cystathionine-beta-Synthase Proteine (CBS)

The protein encoded by CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. Zusätzlich bieten wir Ihnen Cystathionine-beta-Synthase Antikörper (121) und Cystathionine-beta-Synthase Kits (18) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CBS 24250 P32232
CBS 12411 Q91WT9
CBS 875 P35520
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Top Cystathionine-beta-Synthase Proteine auf antikoerper-online.de

Showing 10 out of 15 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$295.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$554.07
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,604.33
Details
Hefe Human His tag   50 μg Anmelden zum Anzeigen 8 bis 11 Tage
$341.00
Details
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
Details
Escherichia coli (E. coli) Yeast His tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
Details
Hefe Yeast His tag   50 μg Anmelden zum Anzeigen 8 bis 11 Tage
$341.00
Details

CBS Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Rat (Rattus)

Mouse (Murine)

Human , , , ,
, , ,

Am meisten referenzierte Cystathionine-beta-Synthase Proteine

  1. Human CBS Protein expressed in Wheat germ - ABIN1348191 : Austgen, Hermann, Dantzler, Rogers, Kline: Hydrogen sulfide augments synaptic neurotransmission in the nucleus of the solitary tract. in Journal of neurophysiology 2011 (PubMed)
    Show all 4 Pubmed References

Weitere Proteine zu Cystathionine-beta-Synthase (CBS) Interaktionspartnern

Chimpanzee Cystathionine-beta-Synthase (CBS) Interaktionspartner

Mouse (Murine) Cystathionine-beta-Synthase (CBS) Interaktionspartner

  1. Results indicate that activation of the cystathionine-beta-synthase (CBS) and its product hydrogen sulfide (zeige SQRDL Proteine) (CBS/H2S axis promotes colon carcinogenesis.

  2. showed that N-homocysteinylation of collagen in Cbs(-/-) mice impairs its cross-linking

  3. the findings of this study indicate that a deficiency in 3MST does not significantly affect endotoxemia, while a deficiency in CBS or CSE (zeige CTH Proteine) slightly ameliorates the outcome of LPS (zeige TLR4 Proteine)-induced endotoxemia in vivo.

  4. These data confirm a key role for the H2S-generating enzymes Cbs and Cth (zeige CTH Proteine) in pulmonary vascular development and homeostasis and in lung alveolarization.

  5. genetic deficiency results in reduced Tet1 (zeige TET1 Proteine) and Tet2 expression, which leads to hypermethylation of Foxp3 (zeige FOXP3 Proteine), and impairment of Treg cell differentiation and immune homeostasis.

  6. Elevated homocytsteine levels in the CBS-/+ mouse skeletal muscles caused diminished anti-oxidant capacity and contributed to enhanced total protein as well as PGC-1alpha specific nitrotyrosylation after ischemia.

  7. CBS disruption causes embryo retention and developmental delay in the mouse oviduct.

  8. CBS is present in adrenocortical cells and accounts for H2S generation in adrenal glands. CBS is critical for maintenance of mitochondrial function and glucocorticoid production in adrenal cortex.

  9. Elevating endogenous H2S via CBS over-expression in immortalized microglia not only reduced the expression of pro-inflammatory M1 genes, but also enhanced the anti-inflammatory M2 marker IL-10 (zeige IL10 Proteine) production.

  10. Cbs protein expression is upregulated in brain cortex following traumatic brain injury.

Human Cystathionine-beta-Synthase (CBS) Interaktionspartner

  1. c.797 G>A (p.R266K) cystathionine beta-synthase mutation has a role in causing homocystinuria by affecting protein stability

  2. The current study observed significant differences in the frequency of the CBS 844ins68 allele across populations. There is a significant association between CBS c.844ins68 polymorphism and cleft lip and palate in the Indian population.

  3. Cystathionine beta-synthase and PGRMC1 (zeige PGRMC1 Proteine) function as carbon monoxide sensors in health and disease. (Review)

  4. These findings may contribute to highlight that the MTHFR (zeige MTHFR Proteine) and CBS polymorphisms involvement in sickle cell anemia (SCA)pathophysiology is likely to be far more complex than it was explored to date

  5. Results indicate that activation of the cystathionine-beta-synthase (CBS) and its product hydrogen sulfide (zeige SQRDL Proteine) (CBS/H2S axis promotes colon carcinogenesis.

  6. Uterine artery hydrogen sulfide (zeige SQRDL Proteine) production is augmented with endothelium and smooth muscle CBS upregulation, contributing to uterine artery vasodilation in the estrogen-dominant physiological states in the proliferative phase of the menstrual cycle and pregnancy.

  7. Common polymorphisms in MTHFR (zeige MTHFR Proteine), methionine synthase (zeige MTR Proteine) and cystathione beta lyase genes have no role in premature acute myocardial infarction in Pakistani population.

  8. Inducible expression of CBS and CSE was found to be associated with a mineralizing phenotype in mesenchymal stem cells transitioning to mineralizing osteoblasts.

  9. SNPs in CBS were not related to relevant changes in homocysteine levels in coronary artery disease patients or controls.

  10. The CBS rs2124459 was associated with a reduced risk of cleft palate in both French and Belgian populations. These results highlight the prominent involvement of the vitamin B6-dependent transsulfuration pathway of homocysteine in orofacial cleft risk and the interest for evaluating vitamin B6 status in further population studies.

Cow (Bovine) Cystathionine-beta-Synthase (CBS) Interaktionspartner

  1. These findings indicate that greater synthesis of phosphatidylcholine (zeige SGMS1 Proteine) and antioxidants contribute to the better performance and immuno-metabolic status in methionine-supplemented cows.

Cystathionine-beta-Synthase (CBS) Protein Überblick

Protein Überblick

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit CBS

  • cystathionine-beta-synthase L homeolog (cbs.L)
  • cystathionine-beta-synthase (cbs)
  • cystathionine beta-synthase (Cbs)
  • cystathionine-beta-synthase (CBS)
  • cystathionine beta-synthase (CNA06170)
  • cystathionine beta-synthase (Tb11.02.5400)
  • cystathionine beta-synthase CBS (cbs)
  • cystathionine beta-synthase (cbs)
  • cystathionine beta-synthase (cysB)
  • cystathionine beta-synthase (LOC100635325)
  • cystathionine beta synthase (Cbs)
  • cystathionine-beta-synthase S homeolog (cbs.S)
  • cystathionine-beta-synthase b (cbsb)
  • AI047524 Protein
  • AI303044 Protein
  • cb442 Protein
  • cbs Protein
  • DDBDRAFT_0189727 Protein
  • DDBDRAFT_0191292 Protein
  • DDB_0189727 Protein
  • DDB_0191292 Protein
  • GB12529 Protein
  • HIP4 Protein
  • wu:fb37g05 Protein
  • wu:fm61c07 Protein
  • wu:fq06c06 Protein
  • zgc:113704 Protein

Bezeichner auf Proteinebene für CBS

cystathionine-beta-synthase , cystathionine beta-synthase , cystathionine beta-synthase CBS , beta-thionase , hemoprotein H-450 , serine sulfhydrase , methylcysteine synthase

GENE ID SPEZIES
380308 Xenopus laevis
493533 Xenopus (Silurana) tropicalis
551341 Apis mellifera
736626 Pan troglodytes
3253577 Cryptococcus neoformans var. neoformans JEC21
3665875 Trypanosoma brucei brucei strain 927/4 GUTat10.1
4551426 Mycobacterium ulcerans Agy99
6228672 Mycobacterium marinum M
7006755 Rhodospirillum centenum SW
7705918 Gemmatimonas aurantiaca T-27
7712188 Rhodococcus erythropolis PR4
7746532 Rhodococcus opacus B4
8616308 Dictyostelium discoideum AX4
100136726 Oncorhynchus mykiss
100635325 Amphimedon queenslandica
24250 Rattus norvegicus
12411 Mus musculus
446655 Xenopus laevis
418545 Gallus gallus
875 Homo sapiens
611071 Canis lupus familiaris
514525 Bos taurus
100008766 Oryctolagus cuniculus
266987 Danio rerio
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