anti-Chromobox Homolog 2 (CBX2) Antikörper

CBX2 encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Zusätzlich bieten wir Ihnen CBX2 Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CBX2 12416 P30658
CBX2 84733 Q14781
CBX2 303730  
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Top anti-CBX2 Antikörper auf antikoerper-online.de

Showing 10 out of 88 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CBX2 Antibody Titration: 0.2-1 ug/ml Positive Control: Human heart Host: Rabbit Target Name: CBX2 Sample Type: Human Fetal Liver Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CBX2 Antibody Titration: 0.2-1 ug/mlPositive Control: OVCAR-3 cell lysate WB Suggested Anti-CBX2 Antibody Titration: 0.2-1 µg/mL Positive Control: OVCAR-3 cell lysate CBX2 is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CBX2 Antibody (N-term) (ABIN653558) in MDA-MB231 cell line lysates (35 µg/lane). CBX2 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Maus Unkonjugiert ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 2:Western blot analysis using CBX2 mAb against human CBX2 (AA: 402-525) recombinant protein. (Expected MW is 38.2 kDa) Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$577.50
Details
Human Maus Unkonjugiert ELISA, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 2:Western blot analysis using CBX2 mAb against human CBX2 (AA: 402-525) recombinant protein. (Expected MW is 38.2 kDa) Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$577.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of CBX2 Antibody (N-term) in MDA-MB231 cell line lysates (35µg/lane). CBX2 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: Cbx2 Antibody [NBP2-47524] - Analysis of human cell line A-431 shows positivity in nucleus but excluded from the nucleoli. Immunohistochemistry: Cbx2 Antibody [NBP2-47524] - Analysis of human stomach shows moderate nuclear positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Maus Kaninchen Unkonjugiert ELISA 50 μL Anmelden zum Anzeigen 2 bis 3 Tage
$185.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details

Weitere Antikörper gegen CBX2 Interaktionspartner

Mouse (Murine) Chromobox Homolog 2 (CBX2) Interaktionspartner

  1. the compaction region of CBX2 plays a key role in establishing proper axial patterning, thereby expanding the functional regions of this protein.

  2. We find that the N-terminus of Cbx2 is needed for its recruitment to mitotic chromosomes, whereas the C-terminus is required for its immobilization.

  3. Cbx2 targets PRC1 to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner.

  4. This study implicates Cbx2 in testis differentiation through regulating Sry gene expression.

  5. Data show that Polycomb repressive complex 2 is necessary to maintain normal levels of OGT and for the correct cellular distribution of O-GlcNAc.

  6. Zfp277 in the transcriptional regulation of the Ink4a/Arf locus and the recruitment of PRC1 to the Ink4a/Arf locus

  7. these results suggest that the binding specificity of Cbx2 protein for methylated histones is regulated by phosphorylation.

  8. murine geminin associates transiently with members of the Hox-repressing polycomb complex, with the chromatin of Hox regulatory DNA elements and with Hox proteins

  9. Polycomb protein M33 controls critical expansion of B- and T-lymphocyte precursors

  10. The Polycomb M33 gene is an essential upstream regulator of Ad4BP/SF1.

  11. We conclude that this amino-acid stretch in M33 acts as the functional nuclear localization signal for this protein

  12. different CBX proteins are recruited to distinct chromatin regions through nonconserved interactions. Metaphase spreads revealed reciprocal patterns of chromosome association by CBX2 and CBX6

  13. Transformations of the axial skeleton are enhanced in compound mutant embryos for the polycomb group gene M33/Cbx2.

Human Chromobox Homolog 2 (CBX2) Interaktionspartner

  1. study indicates a distinct function of the shorter form of CBX2 and by identifying several of its unique targets, can advance our understanding of DSD pathogenesis and ultimately DSD diagnosis and management.

  2. These results suggest that CBX2's phosphorylation is critical for its transcriptional repression of target genes.

  3. Data show that basal-like subgroup was enriched for aggressive tumors and somatic mutations in trithorax-group genes and it overexpressed polycomb genes EZH2 and CBX2.

  4. up-regulated in metastatic castration-resistant prostate cancer and elevated expression correlates with poor clinical outcome

  5. CBX2 role in the sex development cascade is to stimulate the male pathway and concurrently inhibit the female pathway.

  6. CBX2 upregulation and amplification significantly correlated with metastatic progression and lower overall survival in many cancer types, particularly those of the breast

  7. This study does not support CBX2 gene disruption as a common cause of gonadal gonadal disorders of sex development.

  8. Two distinct mechanisms are involved in CBX2-mediated gene silencing. The short CBX2-2 isoform would repress the transcription in a PRC1-independent fashion, whereas gene repression by the long CBX2-1 isoform is mediated by the PRC1 protein complex.

  9. CDYL functions as a molecular bridge between PRC2 and the repressive chromatin mark H3K27me3, forming a positive feedback loop to facilitate the establishment and propagation of H3K27me3 modifications along the chromatin

  10. hPc2 serves as a SUMO E3 ligase for cystathionine beta-synthase, increasing the efficiency of sumoylation.

CBX2 Antigen-Profil

Protein Überblick

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Genbezeichner und Symbole assoziert mit CBX2

  • chromobox 2 (cbx2) Antikörper
  • chromobox 2 (CBX2) Antikörper
  • chromobox homolog 2 (Drosophila Pc class) (cbx2) Antikörper
  • chromobox 2 (Cbx2) Antikörper
  • chromobox 2 L homeolog (cbx2.L) Antikörper
  • cbx2 Antikörper
  • cdca6 Antikörper
  • m33 Antikörper
  • MOD2 Antikörper
  • pc Antikörper
  • pc1 Antikörper
  • SRXY5 Antikörper
  • wu:fd20e09 Antikörper
  • zgc:103563 Antikörper

Bezeichner auf Proteinebene für CBX2

chromobox homolog 2 , modifier 3 protein , chromobox protein homolog 2-like , chromobox homolog 2 (Pc class homolog, Drosophila) , chromobox protein homolog 2 , M33 polycomb-like protein , hromobox homolog 2 , polycomb , Pc class homolog , cell division cycle associated 6 , modifier 3 , Polycomb homolog Pc1 , chromobox homolog 2 (Pc class homolog)

GENE ID SPEZIES
100125497 Oryzias latipes
100410455 Callithrix jacchus
327291 Danio rerio
12416 Mus musculus
84733 Homo sapiens
398110 Xenopus laevis
426248 Gallus gallus
483349 Canis lupus familiaris
303730 Rattus norvegicus
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