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Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. Zusätzlich bieten wir Ihnen CETP Antikörper (118) und CETP Kits (60) und viele weitere Produktgruppen zu diesem Protein an.
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The -629C allele was significantly associated with an increased risk of Coronary heart disease in Caucasians, and this association may be mediated by its phenotypic regulation on circulating CETP and HDL (zeige HSD11B1 Proteine)-C.
inhibitors, especially Torcetrapib and Anacetrapib, increased the binding ratios of the binary complexes (e.g., HDL (zeige HSD11B1 Proteine)-CETP and LDL-CETP) and decreased the binding ratios of the HDL (zeige HSD11B1 Proteine)-CETP-LDL ternary complexes.
Studied association of Cholesterol Ester Transfer Protein (CETP) genetic polymorphisms with acute coronary syndrome; found the frequency of certain genotypes was significantly lower in unstable angina patients, compared with the control group
Inhibiting cholesteryl ester transfer protein activity inhibits vascular smooth muscle cell proliferation, and reduces neointimal hyperplasia in an scavenger receptor-B1, PDZ domain-containing protein 1 (zeige PDZK1 Proteine)- and phosphatidylinositol-3-kinase/Akt (zeige AKT1 Proteine)-dependent manner.
The rs1800775, rs3764261, rs12149545, rs711752, and rs708272 polymorphisms of CETP were associated with metabolic syndrome and its components among the Uyghur ethnic group. Complete linkage disequilibrium was found between two pairs of SNPs (rs3764261 and rs12149545, rs711752, and rs708272).
CETP-inhibition, although effective in improving the lipid profile, is not associated with vascular protective effects as assessed by endothelial function.
The study identified two polymorphisms with a higher risk of age-related macular degeneration development (AMD (zeige AMD1 Proteine)) and also a protective polymorphism for AMD (zeige AMD1 Proteine).
CETP TaqIB polymorphism protects against composite ischemic CVD risk and is associated with a higher HDL (zeige HSD11B1 Proteine)-C concentration in both Asians and Caucasians (Meta-Analysis)
Combined exposure to variants in the genes that encode the targets of CETP inhibitors and statins was associated with discordant reductions in LDL-C and apoB (zeige APOB Proteine) levels and a corresponding risk of cardiovascular events that was proportional to the attenuated reduction in apoB (zeige APOB Proteine) but significantly less than expected per unit change in LDL-C.
Treatment of mildly hypercholesterolemic subjects with CETP inhibitor anacetrapib reduces Lp(a (zeige APOA Proteine)) levels by decreasing its production.
Genetic ablation of CETP activity protects against cholesterol diet-induced atherosclerosis in rabbits.
Cholesteryl ester transfer protein is the sole major determinant of cholesteryl ester transfer in normolipidemic rabbit plasma as a result of the inability of rabbit apoCI to change HDL (zeige HSD11B1 Proteine) electronegativity.
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis.
BPI fold containing family F
, cholesteryl ester transfer protein
, lipid transfer protein I
, Lipid transfer protein I