Calpain 1 Proteine (CAPN1)

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Zusätzlich bieten wir Ihnen CAPN1 Antikörper (110) und CAPN1 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus CAPN1 CAPN1 12333 O35350
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Showing 4 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Human Human Unkonjugiert   100 μg 2 bis 3 Tage
Schwein Schwein Unkonjugiert 100 μg 2 bis 3 Tage
Human Human Unkonjugiert   100 μg 3 bis 4 Tage
Human Unkonjugiert   10 μg 6 Days

CAPN1 Proteine nach Spezies und Herkunft

Origin Exprimiert in
Pig (Porcine)

Am meisten referenzierte CAPN1 Proteine

  1. Human CAPN1 Protein expressed in Human - ABIN411905 : Huang, Zhou, Saberwal, Konieczna, Horvath, Katsoulidis, Platanias, Eklund: Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription. in Molecular and cellular biology 2010 (PubMed)
    Show all 7 Pubmed References

Weitere Proteine zu Calpain 1 (CAPN1) Interaktionspartnern

Mouse (Murine) Calpain 1 (CAPN1) Interaktionspartner

  1. Our data indicate that calpain-1 activity is neuroprotective and calpain-2 activity is neurodegenerative after traumatic Brain Injury

  2. In this chapter we describe a method to knockdown calpain 1 in mouse pulmonary vascular endothelium using delivery of siRNA/cationic liposome complex

  3. 1) that decrease of GLUT3 is associated with the reduction of protein O-GlcNAcylation in Alzheimer's disease (AD)brain, 2) that GLUT3 level is negatively correlated with calpain I activation in human brain, 3) that calpain I proteolyzes GLUT3 at the N-terminus in vitro, and 4) that activation of calpain I is negatively correlated with protein O-GlcNAcylation in AD brain.

  4. Calpain-1 null neutrophils failed to migrate through TNF-activated endothelial monolayers.

  5. Calpain-1 deficiency impairs mGluR-dependent LTD and fear memory extinction.

  6. calpain contributes to the regulation of new gene expression that is necessary for these memory processes as a regulator of Ca(2+)-signal transduction pathway.

  7. the present study suggested that ephrinB/EphB signaling contributes to spinal nociceptive processing via the actions of calpain1 and caspase3.

  8. Authors provide the first evidence that calpain-1 regulates platelet hyperactivity in sickle mice.

  9. A total of 55 genes were differentially expressed in micro-calpain knockout mice.

  10. calpains inhibition plays crucial roles in vascular restenosis by preventing neointimal hyperplasia at the early stage via suppression of the MMP2/TGF-beta1 pathway.

  11. indicate that calpain-1 and calpain-2 play opposite roles in high increased intraocular pressure-induced ischemic injury

  12. Results strengthen the roles of both calpain-1 and PHLPP1 in synaptic plasticity and learning and memory, and illustrate the complexities of the interactions between multiple pathways participating in synaptic plasticity.

  13. Genetic ablation of calpain-1 ameliorates chronic pain behavior in sickle cell mice.

  14. Our results indicate that calpain mediates cytokine-induced collagen-I synthesis and proliferation of ASMCs via the mTORC2/Akt signalling pathway, thereby regulating airway smooth muscle remodelling in asthma.

  15. mutations in CAPN1 are an additional cause of ataxia in mammals, including humans.

  16. Results indicate that calpain-1 and calpain-2 are differentially activated in hippocampus following seizure activity, with calpain-1 activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 is widely activated in pyramidal neurons of CA1 and CA3, and triggers neurodegenerative cascades.

  17. Here we show the combined loss of glial glutamate transporters GLT1 and GLAST in spinal cord caused motor neuronal death and hindlimb paralysis.

  18. These results suggested that Streptococcus pneuomoniae PLY induces the influx of calcium in Streptococcus pneumoniae-infected macrophages, followed by calpain activation and subsequent IL-1alpha maturation and secretion.

  19. High calpain expression is associated with brain injury.

  20. the expression of the full-length 60-kDa calcineurin protein is down-regulated due to over-activated calpain that cleaves calcineurin to form a 45-kDa fragment.

CAPN1 Protein Überblick

Protein Überblick

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

Genbezeichner und Symbole assoziert mit Calpain 1 Proteine (CAPN1)

  • calpain 1 (CAPN1)
  • calpain 1 (Capn1)
  • zgc:55262 (zgc:55262)
  • Capa-1 Protein
  • Capa1 Protein
  • Capn1 Protein
  • fj67g01 Protein
  • mu-calpin Protein
  • wu:fj67g01 Protein

Bezeichner auf Proteinebene für Calpain 1 Proteine (CAPN1)

calpain 1, large subunit , CANP 1 , calcium-activated neutral proteinase 1 , calpain mu-type , calpain-1 catalytic subunit , calpain-1 large subunit , micromolar-calpain , mu-calpain , muCANP , calpain 1

443130 Ovis aries
12333 Mus musculus
406768 Danio rerio
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