anti-CD69 (CD69) Antikörper

Mouse (Murine) CD69 Interaktionspartner

1. This study reveals the importance of CD69 to prolong the thymic residency time of developing immature precursors for proper differentiation of a T cell subset, NKT2 cells.

2. These studies showed that VCAM1 contributes not only to the initiation of myelination but also to its regulation through controlling the abundance of CD69, demonstrating that an intercellular molecule whose primary role is in the immune system can also play an unexpected role in the CNS.

3. AIM plays an orchestrating role in the resolution process of inflammation by altering the profile of pulmonary lipid mediators

4. Data show that a subset of inflammation-induced CD69(+) Kupffer cells which can feedback inhibit CD4 T cell response via cell surface TGF-beta1 at the late stage of immune response against infection.

5. Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance.

6. this study shows that CD69 serves as a key mediator of the pathogenesis of psoriasis by controlling LAT1-CD98-mediated metabolic cues

7. Loss of CD69 is associated with enhanced protection against vaccinia virus infection.

8. The data highlight the contribution of CD69 as a nonredundant key regulator of BIC/miR-155-dependent regulatory T cell development and homeostasis.

9. Data show that after tumor necrosis factor alpha-induced protein 8 like-2 (TIPE2) gene was down-regulated, the expression of the CD69 antigen was increased, and the proliferation of T lymphocytes and the secretion of cytokines IL-2 and IFN-gamma were enhanced.

10. The generation of cancer-specific CD8(+) CD69(+)-expressing lymphocytes that inhibit colon cancer growth has been described.

11. Maintenance of immune tolerance by Foxp3+ regulatory T cells requires CD69 expression.

12. AIM(-/-) mice were highly susceptible to steatosis-associated HCC development, whereas no AIM(+/+) mouse developed the disease despite comparable liver inflammation and fibrosis in response to a long-term high-fat diet.

13. our findings reveal potent strategies to safely increase AIM levels, which could form the basis for developing novel therapies for obesity

14. CD69 interference with S1P1 function regulates peripheral T cell retention.

15. The NKG2A expression was increased in hepatic CD69-NK cells.

16. Report role of ZAP-70 kinase mutation/deletion on thymocyte-positive selection via CD69 signaling.

17. The early activation marker CD69 regulates the expression of chemokines and CD4 T cell accumulation in intestine.

18. Data indicate that CD69 is upregulated on endogenous dendritic cells (DC) upon activation.

19. Intron I acts as an important regulatory element of CD69 expression.

20. Data show that CD69 is critical for the generation and maintenance of professional memory T-helper (Th) lymphocytes, which can efficiently help humoral immunity in the late phase.

Human CD69 Interaktionspartner

1. CD69(+) T cells were associated with disease recurrence.

2. CD69 is a direct target of miR-367-3p.

3. The frequency of CD69+ T cells was significantly higher in CD8+ and CD4+ T cells in nasal polyps compared with the peripheral blood of patients with chronic rhinosinusitis.

4. this paper shows that decrease of CD69 levels on TCR Valpha7.2(+)CD4(+) innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients

5. AIM expression in the kidney was associated with urinary protein and decline in kidney function.

6. Higher CD69 expression were less sensitive to bendamustine and is associated with chronic lymphocytic leukemia.

7. In vitro functional assays showed that CD69(+) Treg cells exerted an important suppressive effect on the activation of T effector cells

8. results demonstrate the functional and mechanistic interplays between CD69 and S100A8/S100A9 in supporting Treg-cell differentiation

9. Elevated expression of CD69 and CD161 on NK cells can be considered as immunological risk markers in RSA and IVF failure.

10. Human tumor-infiltrating CD4+CD69+ T cells suppress T cell proliferation via membarene -bound TGF-beta1.

11. these findings identify CD69 and galectin-1 to be a novel regulatory receptor-ligand pair that modulates Th17 effector cell differentiation and function.

12. REVIEW: CD69 exerts a complex immunoregulatory role in humans, and that it could be considered as a target molecule for the therapy of immune-mediated diseases

13. Following coculture with GTKO/CD46 pig mesenchymal stromal cells, it is possible that upregulation of CD69 on human T cells initiates signaling events that would regulate CD4+ and CD8+ T cell activation and differentiation.

14. In patients with allergic rhinitis CD69 antigen is overexpressed on human peripheral blood natural killer cells reflecting their activation status.

15. This is the first report of the regulation of CD69 expression by LMP-1, and this novel finding may, thus, represent an important link between the EBV oncoprotein LMP-1 and its critical role in the development of EBV-associated diseases.

16. CD69 is induced by integrin alpha4beta1 outside-in signalling and T-cell receptor signalling.

17. CD69 overexpression is associated with the human T-cell leukemia virus type 1 infection and adult T-cell leukemia.

18. Intron I acts as an important regulatory element of CD69 expression.

19. CD69 is significantly correlated with poor clinical and biological prognostic factors and is confirmed to be an independent disease prognosticator in chronic lymphocytic leukemia.

20. Priming with apoptotic debris prevented DCs from establishing cytotoxicity toward live human tumor cells by inducing a Treg-cell population, defined by coexpression of CD39 and CD69