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CLEC11A encodes a member of the C-type lectin superfamily.
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Clec11a maintains the adult skeleton by promoting the differentiation of mesenchymal progenitors into mature osteoblasts.
Data show that asymptomatic patients with unstable plaques exhibited higher levels of endothelial microparticles (EMPs), CXCL9 (zeige CXCL9 ELISA Kits) chemokine (zeige CCL1 ELISA Kits) and stem cell growth factor; lymphocyte secreted C-type lectin (SCGF-beta) compared to those with stable plaques.
This is the first report of SCGF beta in heart failure patients.
The results presented here demonstrate that homozygous T at -539 in the SCGF promoter is associated with elevated SCGF production, enhanced erythropoiesis, and protection against severe malarial anemia.
SCGF is selectively produced by osseous and hematopoietic stromal cells, and can mediate their proliferative activity on primitive hematopoietic progenitor cells.
Results indicate that interleukin-4 (zeige IL4 ELISA Kits), together with recombinant human stem cell factor (zeige KITLG ELISA Kits), can induce T cell maturation from cord blood progenitor cells, and that IL-4 (zeige IL4 ELISA Kits) increased the expression of FcepsilonRI (zeige FCER1G ELISA Kits) on fetal liver mast cells.
Human vascular smooth muscle cells express stem cell factor(SCF (zeige KITLG ELISA Kits)) and its receptor, c-kit (zeige KIT ELISA Kits). SCF (zeige KITLG ELISA Kits) is released from its membrane-bound form via MMP-9 (zeige MMP9 ELISA Kits). SCF (zeige KITLG ELISA Kits)/c-kit (zeige KIT ELISA Kits) signaling may affect SMC (zeige DYM ELISA Kits) function via an autocrine pathway.
phagocytosis of hemozoin promotes a decrease in SCGF gene products, which may contribute to reduced erythropoiesis in children with severe malarial anemia.
In situ hybridization of whole mouse fetuses and their tibias demonstrated expression of SCGF mRNA around skeletal tissues, particularly in bone marrow cells, proliferating chondrocytes, the perichondrium and periosteum.
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.
C-type lectin domain family 11, member A
, stem cell growth factor
, C-type lectin domain family 11 member A
, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 3
, C-type lectin superfamily member 3
, lymphocyte secreted C-type lectin
, lymphocyte secreted long form of C-type lectin
, stem cell growth factor; lymphocyte secreted C-type lectin