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The protein encoded by BNIPL interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. Zusätzlich bieten wir Ihnen BNIPL Proteine (4) und BNIPL Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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These results indicate the presence of two BNIP-S splicing variants as cellular regulators and that the BCH (zeige CHN2 Antikörper) domain of BNIP-Salpha confers a novel apoptotic function. The significance of this is discussed
interaction with cell proliferation-related proteins, MIF (zeige AMH Antikörper) and GFER (zeige GFER Antikörper)
BNIPL-2, a novel homologue of BNIP-2 (zeige BNIP2 Antikörper), interacts with Bcl-2 (zeige BCL2 Antikörper) and Cdc42GAP (zeige ARHGAP1 Antikörper) in apoptosis.
Data suggest that Bcl-2 (zeige BCL2 Antikörper)/adenovirus E1B (zeige BCKDHB Antikörper) 19 ku interacting protein 2-like (BNIPL-2) may regulate apoptosis through changes in the expression of genes associated with cell apoptosis, growth inhibition and cell proliferation.
p16INK4, IL-12 (zeige IL12A Antikörper), TRAIL & lymphotoxin beta (zeige LTB Antikörper) gene involved in growth suppression or cell apoptosis were up-regulated & PTEN was down-regulated by BNIPL-1;suggests that it might inhibit cell growth though cell cycle arrest &/or apoptotic cell death pathway(s)
The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein