anti-Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2) Antikörper

The protein encoded by DARS2 belongs to the class-II aminoacyl-tRNA synthetase family. Zusätzlich bieten wir Ihnen DARS2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DARS2 226539 Q8BIP0
DARS2 304919 Q3KRD0
DARS2 55157 Q6PI48
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Top anti-DARS2 Antikörper auf antikoerper-online.de

Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using DARS2 antibody. Immunohistochemistry of paraffin-embedded human liver injury using DARS2 antibody at dilution of 1:100 (x40 lens). 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert WB Western Blot analysis of DARS2 expression in transfected 293T cell line by DARS2 MaxPab polyclonal antibody.<br><br>Lane 1: DARS2 transfected lysate(73.60 KDa).<br>Lane 2: Non-transfected lysate.<br> DARS2 MaxPab rabbit polyclonal antibody. Western Blot analysis of DARS2 expression in human kidney. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: DARS2 Antibody [NBP1-83854] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: DARS2 Antibody [NBP1-83854] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & mitochondria. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: DARS2 Antibody [NBP2-16102] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:250 dilution. Western Blot: DARS2 Antibody [NBP2-16102] - Sample (30 ug of whole cell lysate) A: MCF-7 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen FITC IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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DARS2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) , ,


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Rat (Rattus) , ,


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Human , ,
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Weitere Antikörper gegen DARS2 Interaktionspartner

Mouse (Murine) Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2) Interaktionspartner

  1. Results now provide the first evidence that loss of DARS2 in neurons leads to strong mitochondrial dysfunction and progressive loss of cells.

  2. DARS2 depletion in heart and skeletal muscle leads to the severe deregulation of mitochondrial protein (zeige COX6B2 Antikörper) synthesis followed by a strong respiratory chain deficit in both tissues.

Human Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2) Interaktionspartner

  1. This study identified DARS2-associated leukoencephalopathy with hypomyelination with brainstem and spinal cord involvement and leg spasticity.

  2. 60 different DARS2 mutations were identified in 78 patients with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation, 13 of which have not been reported before

  3. Cognitive impairment seems to be common among patients with leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate and DARS2 mutations

  4. A comparison of biophysical properties of human mitochondrial aspartyl-tRNA synthetase (zeige DARS Antikörper), HsaDRS2, with them to those of a bacterial (E. coli) homolog, EcoDRS.

  5. Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase (zeige DARS Antikörper) in diverse way

  6. We describe two new cases of Leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate with a novel pathogenic mutation in the DARS2 gene

  7. Case demonstrates that DARS2 mutation homozygosity is not lethal, as suggested earlier, but compatible with a rather benign disease course.

  8. Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA.

  9. A novel homozygous mutation of DARS2 may cause a severe LBSL (Leukoencephalopathy with brain stem and spinal cord involvement with lactate elevation) variant.

  10. This report describes two novel heterozygote composite mutations in the DARS2 gene

DARS2 Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).

Genbezeichner und Symbole assoziert mit DARS2

  • aspartyl-tRNA synthetase 2, mitochondrial (DARS2) Antikörper
  • aspartyl-tRNA synthetase 2, mitochondrial (dars2) Antikörper
  • aspartate--tRNA ligase, mitochondrial (LOC100547893) Antikörper
  • aspartyl-tRNA synthetase 2 (mitochondrial) (Dars2) Antikörper
  • 5830468K18Rik Antikörper
  • ASPRS Antikörper
  • LBSL Antikörper
  • MT-ASPRS Antikörper
  • RGD1308286 Antikörper
  • RP3-383J4.2 Antikörper
  • si:dkey-21n10.1 Antikörper

Bezeichner auf Proteinebene für DARS2

aspartyl-tRNA synthetase 2, mitochondrial , aspartyl-tRNA synthetase 2 (mitochondrial) , aspartyl-tRNA synthetase, mitochondrial , aspartyl-tRNA synthetase, mitochondrial-like , aspRS , aspartate--tRNA ligase, mitochondrial , aspartate tRNA ligase 2, mitochondrial

GENE ID SPEZIES
424408 Gallus gallus
469591 Pan troglodytes
490337 Canis lupus familiaris
571144 Danio rerio
707002 Macaca mulatta
100061003 Equus caballus
100145033 Xenopus (Silurana) tropicalis
100173764 Pongo abelii
100344833 Oryctolagus cuniculus
100401842 Callithrix jacchus
100547893 Meleagris gallopavo
100602031 Nomascus leucogenys
226539 Mus musculus
304919 Rattus norvegicus
55157 Homo sapiens
538772 Bos taurus
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