anti-Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) Antikörper

ASB2 encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. Zusätzlich bieten wir Ihnen ASB2 Proteine (4) und ASB2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ASB2 51676 Q96Q27
ASB2 65256 Q8K0L0
ASB2 299266 Q5U2S6
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Top anti-ASB2 Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB ASB2 Antibody (N-term)  western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the ASB2 antibody detected the ASB2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB 200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Asb-2 using ABIN252587 at 1:1,000 dilution against 15 ug/lane of human spleen lysate (lane 1) and lung lysate (lane 2). Western Blot: ASB2 Antibody [ABIN2525878] - Analysis of Asb-2 in HL60 cell lysate using this antibody at 1:1000 dilution. 0.2 mL Anmelden zum Anzeigen 7 bis 9 Tage
$345.00
Details
Human Maus Unkonjugiert IHC (p)   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemistry: ASB2 Antibody (4C2) [NBP2-46546] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) Immunohistochemistry: ASB2 Antibody (4C2) [NBP2-46546] - Analysis of Carcinoma of Human prostate tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$793.83
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged ASB2 is 1 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
Details
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

ASB2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ASB2 Antikörper

  1. Human Polyclonal ASB2 Primary Antibody für WB - ABIN537369 : Temmerman, Ma, Borges, Kubin, Liu, Derry, Jain: Impaired dendritic-cell function in ectodermal dysplasia with immune deficiency is linked to defective NEMO ubiquitination. in Blood 2006 (PubMed)

Weitere Antikörper gegen ASB2 Interaktionspartner

Human Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) Interaktionspartner

  1. Using ASB2 conditional knockout mice.

  2. Phosphorylation of serine 323 of ASB2 alpha by Erk (zeige EPHB2 Antikörper) kinases is critical for ASB2alpha-mediated degradation of FLNA (zeige FLNA Antikörper).

  3. data therefore reveal ubiquitin acceptor sites in FLNa (zeige FLNA Antikörper) and establish that ASB2alpha-mediated effects on cell spreading are due to loss of filamins.

  4. Data show that neither endogenous nor exogenously expressed ASB2alpha induces degradation of JAK (zeige JAK3 Antikörper) proteins in hematopoietic cells

  5. A model whereby ASB2 contributes to hematopoietic differentiation, in part, through MLL (zeige MLL Antikörper) degradation and HOX (zeige MSH2 Antikörper) gene down-regulation.

  6. By shifting monomeric E3 ligase complexes to dimeric forms through activation of Asb2 transcription, Notch (zeige NOTCH1 Antikörper) could effectively control the turnover of a variety of substrates and it exerts diverse effects on cell proliferation and differentiation.

  7. ASB2 may regulate hematopoietic cell differentiation by modulating cell spreading and actin remodeling through targeting of filamins A and B for degradation.

Mouse (Murine) Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) Interaktionspartner

  1. This study identifies desmin (zeige DES Antikörper) as a new Asb2b target for proteasomal degradation in cardiomyocytes and suggests that accumulation of desmin (zeige DES Antikörper) could contribute to UPS impairment in Hypertrophic cardiomyopathy mice and patients

  2. ASB2(-/-) immature dendritic cells exhibit reduced matrix-degrading function leading to defective migration.

  3. ASB2beta is part of an active E3 ubiquitin ligase (zeige MUL1 Antikörper) complex and targets the actin-binding protein (zeige PFN1 Antikörper) filamin B (zeige FLNB Antikörper) for proteasomal degradation.

ASB2 Antigen-Profil

Protein Überblick

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit ASB2

  • ankyrin repeat and SOCS box containing 2 (ASB2) Antikörper
  • ankyrin repeat and SOCS box-containing 2 (Asb2) Antikörper
  • 1110008E15Rik Antikörper
  • ASB-2 Antikörper
  • ASB2 Antikörper

Bezeichner auf Proteinebene für ASB2

ankyrin repeat and SOCS box-containing 2 , ankyrin repeat and SOCS box protein 2-like , ankyrin repeat and SOCS box protein 2 , ankyrin repeat and SOCS box-containing protein 2a , ASB-2 , ankyrin repeat and SOCS box-containing protein 2 , ankyrin repeat-containing SOCS box protein 2

GENE ID SPEZIES
100064381 Equus caballus
423428 Gallus gallus
467538 Pan troglodytes
490836 Canis lupus familiaris
699882 Macaca mulatta
100227715 Taeniopygia guttata
100385735 Callithrix jacchus
100451651 Pongo abelii
51676 Homo sapiens
539244 Bos taurus
65256 Mus musculus
299266 Rattus norvegicus
Ausgewählte Anbieter für anti-ASB2 (ASB2) Antikörper
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