anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antikörper

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Anmelden zum Anzeigen 10 bis 15 Tage
$531.13
Details
Human Maus Unkonjugiert IF, IP, WB   100 μL Anmelden zum Anzeigen 16 Days
$405.08
Details
Human Maus Unkonjugiert FACS, IF, IHC, WB   500 μL Anmelden zum Anzeigen 11 bis 16 Tage
$689.86
Details
Human Kaninchen Unkonjugiert IHC   50 μg Anmelden zum Anzeigen 11 bis 16 Tage
$762.14
Details
Human Maus Unkonjugiert IC, IHC, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$587.71
Details
Human Maus Unkonjugiert FACS, IHC, WB   100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$762.14
Details
Human Maus Unkonjugiert IC, FACS, IHC, WB   250 μg Anmelden zum Anzeigen 11 bis 16 Tage
$829.71
Details
Human Ratte Unkonjugiert IC, FACS, IHC, WB   125 μg Anmelden zum Anzeigen 11 bis 16 Tage
$843.86
Details
Human Maus Unkonjugiert IC, FACS, IHC, WB   250 μg Anmelden zum Anzeigen 11 bis 16 Tage
$1,309.00
Details

Am meisten referenzierte anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper

  1. Human Polyclonal ABCB1B Primary Antibody für FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Interaktionspartner

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. This study demonstrated that the The G2677T T and C3435T T alleles as well as the TT, CTT (zeige TNNT2 Antikörper) and TTT haplotypes seemed to be significantly associated with drug-resistance epilepsy in Tunisian epileptic population.

  2. Pharmacokinetics of aripiprazole is affected by sex and ABCB1 (zeige ABCB1 Antikörper) gene phenotype

  3. There were no significant differences in the bosutinib C0 between genotypes for ABCB1 (zeige ABCB1 Antikörper), ABCG2, and CYP3A4 (zeige CYP3A4 Antikörper) polymorphisms.

  4. Studies show a connection between UDP-glucose ceramide glucosyltransferase (UGCG (zeige UGCG Antikörper)) and multidrug resistance protein 1 (MDR1 (zeige ABCB4 Antikörper)) overexpression and multidrug resistance development [Review].

  5. Due to the downregulation of MDR1 (zeige TBC1D9 Antikörper) and MRP1 (zeige MDM4 Antikörper), the intracellular accumulation of ADM (zeige ADM Antikörper) was increased in the transfected cells compared with that in the parental K562/ADM (zeige ADM Antikörper) cells..Our research revealed that protein expression of the ERK (zeige EPHB2 Antikörper) signaling pathway was inhibited by downregulating TRIB2 (zeige TRIB2 Antikörper), indicating that the ERK (zeige EPHB2 Antikörper) pathway was involved in cell drug resistance and proliferation.

  6. Asiatic Acid strongly inhibited P-GP (zeige ABCB4 Antikörper) expression by blocking MDR1 (zeige TBC1D9 Antikörper) gene transcription and increased the intracellular accumulation of the P-GP (zeige ABCB4 Antikörper) substrate Rhodamine 123 in MDR1 (zeige TBC1D9 Antikörper)-overexpressing cisplatin (DDP (zeige TIMM8A Antikörper))-resistant lung cancer cells, A549/DDP (zeige TIMM8A Antikörper).

  7. Ceritinib enhanced the efficacy of substrate chemotherapeutic agent in ABCB1 (zeige ABCB1 Antikörper)-overexpressing K562/adr (zeige AKR1B1 Antikörper) leukemia cells both in vitro and in vivo models, but neither in sensitive parental K562 leukemia cells nor in ABCC1 (zeige ABCC1 Antikörper)-overexpressing HL-60/adr (zeige AKR1B1 Antikörper) leukemia cells.

  8. Polymorphism of ABCB1 (zeige ABCB1 Antikörper) rs1045642-T variant allele is associated with colorectal cancer.

  9. There is a certain correlation between the APC (zeige APC Antikörper) gene and ovarian tumors, and the APC (zeige APC Antikörper) gene mediates the apoptosis of tumor cells through the MDR-1 (zeige TBC1D9 Antikörper)/CLCX-1 signaling pathway.

  10. ABCB1/Pgp (zeige ABCB4 Antikörper) expression, activity, and single nucleotide polymorphisms (SNPs) in chronic myeloid leukemia (zeige BCL11A Antikörper). [review]

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. this study shows that MDR1 (zeige ABCB4 Antikörper) deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation

  2. A panel of 18 P-gp (zeige ABCB4 Antikörper) substrates were administered into the airways of an isolated perfused mouse lung (IPML) model derived from Mdr1a (zeige ABCB4 Antikörper)/Mdr1b knockout mice. Parallel intestinal absorption studies were performed. Lung P-gp (zeige ABCB4 Antikörper) can affect the pulmonary kinetics of a subset of P-gp (zeige ABCB4 Antikörper) substrates.

  3. Data suggest that the overexpression of P-gp (zeige ABCB4 Antikörper) in neoplastic cells may be associated with alterations in O-glycosylated cell surface proteins, including mucins, and this alteration may be responsible for the reduced cell sensitivity to the O-glycosylation inhibitor GalNAc-alpha-O-benzyl.

  4. We conclude that mdr1b and bcrp are essential to ovarian protection from chemotoxicity and may have an important physiological role in the ovary.

  5. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (zeige ABCB4 Antikörper), multi-drug resistance protein, MDR1 (zeige ABCB4 Antikörper)).Drugs with ER < 1 (zeige MIER1 Antikörper) almost do not bind the main binding cavity (MBC (zeige CACNA1C Antikörper)) of P-gp (zeige ABCB4 Antikörper).

  6. conclusion, MDR1 (zeige ABCB4 Antikörper) and BCRP are expressed on apical membranes of the rodent placental SynT (zeige STX1A Antikörper)-II layer.

  7. Mdr1 (zeige ABCB4 Antikörper) enforces T Cell homeostasis in the presence of intestinal bile acids.

  8. Loss of ABCB1 (zeige ABCB1 Antikörper) expression is associated with neonatal hyperbilirubinemia.

  9. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (zeige ABCB4 Antikörper) ATPase (zeige DNAH8 Antikörper) activity

  10. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antigen-Profil

Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Genbezeichner und Symbole assoziert mit ABCB1B

  • ATP binding cassette subfamily B member 1 (ABCB1) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ABC20 Antikörper
  • Abcb1 Antikörper
  • CD243 Antikörper
  • CLCS Antikörper
  • GP170 Antikörper
  • mdr Antikörper
  • Mdr1 Antikörper
  • Mdr1b Antikörper
  • P-GP Antikörper
  • Pgy-1 Antikörper
  • Pgy1 Antikörper

Bezeichner auf Proteinebene für ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPEZIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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