anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antikörper

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper auf antikoerper-online.de

Showing 10 out of 46 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL 3 bis 7 Tage
$329.45
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Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg 10 bis 15 Tage
$521.89
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Human Maus Unkonjugiert IF, IP, WB   100 μL 11 bis 13 Tage
$405.08
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Human Maus Unkonjugiert FACS, IF, IHC, WB   500 μL 11 bis 16 Tage
$732.29
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Human Kaninchen Unkonjugiert IHC   50 μg 11 bis 16 Tage
$762.14
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Human Maus Unkonjugiert IC, IHC, WB   100 μg 11 bis 16 Tage
$587.71
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Human Maus Unkonjugiert FACS, IHC, WB   100 μL 11 bis 16 Tage
$762.14
Details
Human Maus Unkonjugiert IC, FACS, IHC, WB   250 μg 11 bis 16 Tage
$843.86
Details
Human Ratte Unkonjugiert IC, FACS, IHC, WB   125 μg 11 bis 16 Tage
$861.14
Details
Human Maus Unkonjugiert IC, FACS, IHC, WB   250 μg 11 bis 16 Tage
$1,335.71
Details

Am meisten referenzierte anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper

  1. Human Polyclonal ABCB1B Primary Antibody für FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Interaktionspartner

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. The results reveal the potential regulatory mechanism of FTH1P3 on breast cancer paclitaxel resistance through miR-206/ABCB1 axis.

  2. Crown ethers reverse P-glycoprotein-mediated multidrug resistance in cancer cells.

  3. High MDR1 expression is associated with acute lymphoblastic leukemia.

  4. The study demonstrated that the simultaneous presence of TMDR1, A CYP2D6*4 and A NAT2*7 alleles robustly increased the risk of developing ulcerative colitis by 3.49-fold. The current study suggests that CYP2D6*4 and MDR1 3435 C/T gene polymorphisms may be risk factors for UC susceptibility.

  5. HIF1A-induced MDR1 and MRP4 promote Th17 responses in Crohn's disease.

  6. In conclusion, we provide evidence that P-gp may be involved in an AhR-dependent detoxification process induced in response to the uremic toxin IS.

  7. sofosbuvir GS-331007 metabolite plasma levels were affected by variants in the ABCB1 and HNFalpha genes

  8. The contribution of polymorphisms in ABCB1 to drug pharmacokinetics.

  9. FENDRR attenuates NSCLC cell stemness through inhibiting the HuR/MDR1 axis

  10. Significant associations between SNPs in MDR1 and outcome of multiple myeloma (MM) were found in 110 MM patients that underwent bortezomib-based treatment.

  11. WBP2 directly promoted P-glycoprotein expression through binding to ERalpha to increase the doxorubicin resistance of ERalpha-positive MCF-7 cells.

  12. this study shows that high MDR-1 expression by mucosal-associated invariant T cells confers resistance to cytotoxic but not immunosuppressive MDR-1 substrates

  13. A correlation exists between the ABCB1 C3435T gene polymorphism and post-stroke depression in the Han population in South Anhui province, China.

  14. elevated levels of ABCB1 gene expression are associated with response to metformin with chemotherapy in acute lymphoblastic leukemia

  15. There was no significant association between Tac-related nephrotoxicity and donor CYP3A5 and ABCB1 genotype.

  16. WYE354 stimulated the ATPase activity of ABCB1, which was consistent with in silico predictions using a human ABCB1 mouse homology model, indicating that WYE354 is a potent substrate of ABCB1.

  17. ABCB1 is involved in neo-absorbed vitamin D efflux by the enterocytes and that it also contributes to vitamin D transintestinal excretion and likely impacts vitamin D status.

  18. this study determined the 3.5-angstrom cryo-electron microscopy structure of substrate-bound human ABCB1 reconstituted in lipidic nanodiscs, revealing a single molecule of the chemotherapeutic compound paclitaxel (Taxol) bound in a central, occluded pocket.

  19. CCL20 enhanced doxorubicin resistance of OC cells by regulating ABCB1 expression

  20. MDR1 (rs1045642) and CYP46A1 (rs754203) genes polymorphism was not found associated with Fasting Blood Sugar (FBS), Diastolic Blood Pressure (DBP) or Systolic Blood Pressure (SBP).

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. ABCB1 is involved in neo-absorbed vitamin D efflux by the enterocytes and that it also contributes to vitamin D transintestinal excretion and likely impacts vitamin D status.

  2. esults suggest that P-gp plays important role in mediating rivastigmine non-cholinergic beneficial effects, including Abeta brain load reduction, neuroprotective and anti-inflammatory effects in the AD mouse models.

  3. this study shows that MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation

  4. A panel of 18 P-gp substrates were administered into the airways of an isolated perfused mouse lung (IPML) model derived from Mdr1a/Mdr1b knockout mice. Parallel intestinal absorption studies were performed. Lung P-gp can affect the pulmonary kinetics of a subset of P-gp substrates.

  5. Data suggest that the overexpression of P-gp in neoplastic cells may be associated with alterations in O-glycosylated cell surface proteins, including mucins, and this alteration may be responsible for the reduced cell sensitivity to the O-glycosylation inhibitor GalNAc-alpha-O-benzyl.

  6. We conclude that mdr1b and bcrp are essential to ovarian protection from chemotoxicity and may have an important physiological role in the ovary.

  7. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp, multi-drug resistance protein, MDR1).Drugs with ER < 1 almost do not bind the main binding cavity (MBC) of P-gp.

  8. conclusion, MDR1 and BCRP are expressed on apical membranes of the rodent placental SynT-II layer.

  9. Mdr1 enforces T Cell homeostasis in the presence of intestinal bile acids.

  10. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  11. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp ATPase activity

  12. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  13. Chrysosplenetin inhibited P-gp activity and reverse the up-regulated P-gp and MDR1 levels induced by artemisinin.

  14. Tamsulosin and tolterodine with P-gp gene expression and activity in an enantiomer-specific way.

  15. Pgp-coupled ATPase activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  16. Data show that human transgenic mutant huntingtin (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1) which suggests that MDR1 might be a potential therapeutic target for Huntington's disease.

  17. In vitro and in vivo downregulation of the ATP binding cassette transporter B1 by the HMG-CoA reductase inhibitor simvastatin

  18. Efficient chemoprotection of CDD and MDR1 transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara-C and anthracycline application

  19. Mdr1b participates in the elimination of paraquat from the kidneys and protects against subsequent toxicity.

  20. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp substrates.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antigen-Profil

Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Genbezeichner und Symbole assoziert mit ABCB1B

  • ATP binding cassette subfamily B member 1 (ABCB1) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ABC20 Antikörper
  • Abcb1 Antikörper
  • CD243 Antikörper
  • CLCS Antikörper
  • GP170 Antikörper
  • mdr Antikörper
  • Mdr1 Antikörper
  • Mdr1b Antikörper
  • P-GP Antikörper
  • Pgy-1 Antikörper
  • Pgy1 Antikörper

Bezeichner auf Proteinebene für ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPEZIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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