anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antikörper

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper auf antikoerper-online.de

Showing 10 out of 31 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$438.96
Details
Human Maus Unkonjugiert IF, IP, WB   100 μL Anmelden zum Anzeigen 16 Days
$405.08
Details
Human Maus Unkonjugiert IC, FACS, IHC, WB   250 μg Anmelden zum Anzeigen 11 bis 16 Tage
$771.57
Details
Human Ratte Unkonjugiert IC, FACS, IHC, WB   125 μg Anmelden zum Anzeigen 11 bis 16 Tage
$795.14
Details
Human Maus Unkonjugiert IC, FACS, IHC, WB   125 μg Anmelden zum Anzeigen 11 bis 16 Tage
$807.71
Details
Human Maus Unkonjugiert WB   100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$570.43
Details
Human Maus Unkonjugiert IC, FACS, IP, IHC, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$672.57
Details
Human Maus Unkonjugiert IC, FACS, IP   1 mL Anmelden zum Anzeigen 11 bis 16 Tage
$707.14
Details
Human Maus Unkonjugiert FACS, IF, IHC, WB   500 μL Anmelden zum Anzeigen 11 bis 16 Tage
$689.86
Details

ABCB1B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, ,
,
, , ,
Mouse (Murine) ,
,
,
Rat (Rattus) ,
,
,

Am meisten referenzierte anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper

  1. Human Polyclonal ABCB1B Primary Antibody für FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Interaktionspartner

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. Results show that CD133 and MDR1 (zeige TBC1D9 Antikörper) expression increase in recurrent pediatric pilocytic astrocytomas (PAs (zeige PASK Antikörper)) following chemotherapy, and in drug resistant tumor cells. CD133 regulates MDR1 (zeige TBC1D9 Antikörper) expression via the PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signaling. These results provide evidence that CD133 contributes to multidrug resistance by regulating MDR1 (zeige TBC1D9 Antikörper) levels via the PI3K (zeige PIK3CA Antikörper)-Akt (zeige AKT1 Antikörper)-NF-kappaB (zeige NFKB1 Antikörper) signal pathway.

  2. PG accumulation assay is a new, unique tool for the parallel determination of the function of the ABCG2 (zeige ABCG2 Antikörper), ABCB1 (zeige ABCB1 Antikörper), and ABCC1 (zeige ABCC1 Antikörper) multidrug transporters

  3. Abcb1a (zeige ABCB1 Antikörper)/b(-/-);Abcg2 (zeige ABCG2 Antikörper)(-/-) mice revealed increased brain penetration of rapamycin (13-fold), AZD8055 (7.7-fold), and NVP-BEZ235 (4.5-fold), but not ZSTK474 relative to WT mice. Importantly, ABC (zeige ABCB6 Antikörper) transporters limited rapamycin brain penetration to subtherapeutic levels, while the reduction in NVP-BEZ235 brain penetration did not prevent target inhibition.

  4. ABCB1 (zeige ABCB1 Antikörper) genotype is not a significant determinant of interindividual variability in dabigatran and rivaroxaban pharmacokinetics

  5. High MDR1 (zeige TBC1D9 Antikörper) expression is associated with multidrug resistance in breast cancer.

  6. inhibition of autophagy led to the decrease in stemness, restoration of mitochondrial proteins and reduced expression of CD44 (zeige CD44 Antikörper), ABCB1 (zeige ABCB1 Antikörper) and ADAM17 (zeige ADAM17 Antikörper)

  7. The T-allele of ABCB1 (zeige ABCB1 Antikörper)-C3435T gene polymorphism has demonstrated to be a good prognosis factor for resistance, progression free survival and overall survival in HER2 (zeige ERBB2 Antikörper)-positive Breast Cancer patients.

  8. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (zeige ABCB4 Antikörper)--{REVIEW}

  9. Studied ABCB1 (zeige ABCB1 Antikörper) protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1 (zeige ABCB1 Antikörper)-expressing neurons in the left habenula.

  10. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (zeige ABCC6 Antikörper), ABCB1 (zeige ABCB1 Antikörper) and CYP2C8 (zeige CYP2C8 Antikörper) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Interaktionspartner

  1. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (zeige ABCB4 Antikörper), multi-drug resistance protein, MDR1 (zeige ABCB4 Antikörper)).Drugs with ER < 1 (zeige MIER1 Antikörper) almost do not bind the main binding cavity (MBC (zeige CACNA1C Antikörper)) of P-gp (zeige ABCB4 Antikörper).

  2. conclusion, MDR1 (zeige ABCB4 Antikörper) and BCRP (zeige ABCG2 Antikörper) are expressed on apical membranes of the rodent placental SynT (zeige STX1A Antikörper)-II layer.

  3. Mdr1 (zeige ABCB4 Antikörper) enforces T Cell homeostasis in the presence of intestinal bile acids.

  4. Loss of ABCB1 (zeige ABCB1 Antikörper) expression is associated with neonatal hyperbilirubinemia.

  5. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (zeige ABCB4 Antikörper) ATPase (zeige DNAH8 Antikörper) activity

  6. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  7. Chrysosplenetin inhibited P-gp (zeige ABCB4 Antikörper) activity and reverse the up-regulated P-gp (zeige ABCB4 Antikörper) and MDR1 (zeige ABCB4 Antikörper) levels induced by artemisinin.

  8. Tamsulosin and tolterodine with P-gp (zeige ABCB4 Antikörper) gene expression and activity in an enantiomer-specific way.

  9. Pgp (zeige ABCB4 Antikörper)-coupled ATPase (zeige DNAH8 Antikörper) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  10. Data show that human transgenic mutant huntingtin (zeige HTT Antikörper) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (zeige ABCB4 Antikörper)) which suggests that MDR1 (zeige ABCB4 Antikörper) might be a potential therapeutic target for Huntington's disease.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antigen-Profil

Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Genbezeichner und Symbole assoziert mit ABCB1B

  • ATP binding cassette subfamily B member 1 (ABCB1) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ABC20 Antikörper
  • Abcb1 Antikörper
  • CD243 Antikörper
  • CLCS Antikörper
  • GP170 Antikörper
  • mdr Antikörper
  • Mdr1 Antikörper
  • Mdr1b Antikörper
  • P-GP Antikörper
  • Pgy-1 Antikörper
  • Pgy1 Antikörper

Bezeichner auf Proteinebene für ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPEZIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
Ausgewählte Anbieter für anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antikörper
Haben Sie etwas anderes gesucht?