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May play a role in lysosomes motility. Zusätzlich bieten wir Ihnen ADP-Ribosylation Factor-Like 8B Kits (13) und ADP-Ribosylation Factor-Like 8B Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Authors present evidence that Arl8b facilitates lipid hydrolysis to maintain efficient metabolism for a proliferative capacity in low nutrient environments, suggesting a likely explanation for the complete inability of Arl8b-depleted tumor cells to grow in vivo.
LAMTOR1 (zeige LAMTOR1 Antikörper) is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.
Data indicate that E3 ubiquitin-protein ligase RNF167 (zeige RNF167 Antikörper) ubiquitinates Arl8B at the lysine residue K141 and reduces the level of the ADP-ribosylation factor-like 8B Arl8B protein.
Arl8b regulates the association of the human HOPS (zeige ALPL Antikörper) complex with lysosomal membranes.
a small GTP-binding protein (zeige ARF3 Antikörper), ADP-ribosylation factor-like 8b (Arl8b), is identified as a critical factor required for NK cell-mediated cytotoxicity.
The authors find that Arl8B is required for kinesin-1 recruitment to Salmonella-containing vacuoles, migration of the vacuoles to the cell periphery 24 h after infection and for cell-to-cell transfer of bacteria to neighbouring cells.
Results suggest that the novel GTPases Gie1 and Gie2 (zeige ARL8A Antikörper) associate with microtubules, and might be involved in chromosome segregation.
Arl8b is involved in trafficking processes for lysosomes.
Data show that with MAK3 (zeige NAA30 Antikörper) knockdown, p53 (zeige TP53 Antikörper) is stabilized and phosphorylated and there is a significant transcriptional activation of proapoptotic genes downstream of p53 (zeige TP53 Antikörper), and that localization of Arl8b is altered, suggesting that Arl8b is a Mak3 (zeige NAA30 Antikörper) substrate.
MHC class II presentation is controlled by the lysosomal Arl8b.
Arl8B is required for LPS (zeige TLR4 Antikörper)-stimulated lysosome tubulation in macrophages.
Arl8B plays an important role of Arl8B in neurite formation.
May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity).
ADP-ribosylation factor-like 10C
, ADP-ribosylation factor-like protein 10C
, ADP-ribosylation factor-like protein 8B
, novel small G protein indispensable for equal chromosome segregation 1
, small G protein indispensable for equal chromosome segregation 1