anti-Cyclin E1 (CCNE1) Antikörper

Bezeichnung:
anti-Cyclin E1 Antikörper (CCNE1)
Auf www.antikoerper-online.de finden Sie aktuell 281 Cyclin E1 (CCNE1) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Cyclin E1 Kits (20) und Cyclin E1 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 342 Cyclin E1 Produkte verfügbar.
Synonyme:
AW538188, Ccne, CCNE1, cyce, CycE1, cyce2, cycE3, CYCLE, cyclinE, fa18e07, wu:fa18e07
Alle Antikörper anzeigen Gen GeneID UniProt
CCNE1 898 P24864
CCNE1 12447 Q61457
CCNE1 25729  

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Meistgesuchte Reaktivitäten zu anti-Cyclin E1 (CCNE1) Antikörper

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anti-Human Cyclin E1 Antikörper:

anti-Mouse (Murine) Cyclin E1 Antikörper:

anti-Rat (Rattus) Cyclin E1 Antikörper:

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Am meisten referenzierte anti-Cyclin E1 Antikörper

  1. Human Monoclonal Cyclin E1 Primary Antibody für IHC (fro), IHC (p) - ABIN114787 : Faha, Harlow, Lees: The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2. in Journal of virology 1993 (PubMed)
    Zeige alle 7 Referenzen für 114787

  2. Human Polyclonal Cyclin E1 Primary Antibody für FACS, IHC (p) - ABIN390209 : Ausserlechner, Obexer, Geley, Kofler: G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression. in Leukemia 2005 (PubMed)
    Zeige alle 5 Referenzen für 390209

  3. Human Polyclonal Cyclin E1 Primary Antibody für EIA, WB - ABIN358767 : Honda, Lowe, Dubinina, Skamnaki, Cook, Brown, Johnson: The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles. in The EMBO journal 2005 (PubMed)
    Zeige alle 4 Referenzen für 358767

  4. Human Polyclonal Cyclin E1 Primary Antibody für IF, ELISA - ABIN1531430 : Koff, Cross, Fisher, Schumacher, Leguellec, Philippe, Roberts: Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. in Cell 1991 (PubMed)
    Zeige alle 2 Referenzen für 1531430

  5. Human Polyclonal Cyclin E1 Primary Antibody für IF, IHC - ABIN1532446 : Geng, Eaton, Picón, Roberts, Lundberg, Gifford, Sardet, Weinberg: Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. in Oncogene 1996 (PubMed)
    Zeige alle 2 Referenzen für 1532446

  6. Mouse (Murine) Polyclonal Cyclin E1 Primary Antibody für FACS, IF (p) - ABIN670311 : Xu, Zhang, Li, Li, Zhang: Concentration-Dependent Diversifcation Effects of Free Cholesterol Loading on Macrophage Viability and Polarization. in Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015 (PubMed)

  7. Human Monoclonal Cyclin E1 Primary Antibody für FACS, IF - ABIN567783 : Murakami-Mori, Mori, Nakamura: Endogenous basic fibroblast growth factor is essential for cyclin E-CDK2 activity in multiple external cytokine-induced proliferation of AIDS-associated Kaposi's sarcoma cells: dual control of AIDS-associated Kaposi's sarcoma cell growth and cyclin E-CDK2 in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)

Weitere Antikörper gegen Cyclin E1 Interaktionspartner

Human Cyclin E1 (CCNE1) Interaktionspartner

  1. Inhibition of cell division cycle associated 2 (CDCA2 (zeige CDCA2 Antikörper)) suppressed the proliferation of lung adenocarcinoma (LAC (zeige LCT Antikörper)) cells via G1 phase arrest by downregulating cyclin E1(CCNE1), while overexpression of CDCA2 (zeige CDCA2 Antikörper) promoted LAC (zeige LCT Antikörper) cells proliferation by upregulating CCNE1.

  2. a PI3K (zeige PIK3CA Antikörper)/PKCiota/cyclin E signaling pathway as a therapeutic target during ovarian tumorigenesis

  3. Amplification of the G1-S regulatory genes, CCNE1, CCND1 and CdK6, represent an early event, which precedes ERBB2, EGFR, or KRAS amplification in gastric adenocarcinoma.

  4. Amplification of 19q12 CCNE1/URI (zeige C19orf2 Antikörper) was found in 10.4% (28/270) and was significantly associated with type II endometrial cancer (EC) high grade, advanced FIGO stage, and aberrant tumor supressor p53 (zeige TP53 Antikörper) expression.

  5. Data reveal that the presence of rs200996365, a SNP in high-linkage disequilibrium with rs8102137 residing in the center of a KLF5 (zeige KLF5 Antikörper) motif, alters KLF5 (zeige KLF5 Antikörper) binding to this genomic region and provide evidence that KLF5 (zeige KLF5 Antikörper) binds CCNE1 polymorphic intronic enhancer to confer increased bladder cancer risk.

  6. Noxin (zeige C11orf82 Antikörper) facilitated the expression of Cyclin D1 (zeige CCND1 Antikörper) and Cyclin E1 through activating P38 (zeige CRK Antikörper)-activating transcription factor 2 (zeige ATF2 Antikörper) signaling pathway, thus enhanced cell growth of breast cancer

  7. Results show that cyclin E1 and CDK2 (zeige CDK2 Antikörper) participate in STC1 (zeige STC1 Antikörper) promoting cell proliferation of prostate neoplasm cells.

  8. cyclin E is specifically dephosphorylated at S384 by the PP2A (zeige PPP2R4 Antikörper)-B56 phosphatase, thereby uncoupling cyclin E degradation from cyclin E-CDK2 (zeige CDK2 Antikörper) activity

  9. These results provide evidence that ARTD1 (zeige PARP1 Antikörper) regulates cell cycle re-entry and G1/S progression via cyclin E expression and p27 (zeige PAK2 Antikörper)(Kip 1 (zeige CDKN1B Antikörper)) stability independently of its enzymatic activity, uncovering a novel cell cycle regulatory mechanism.

  10. These results demonstrate a repressor role for NFAT1 (zeige NFAT1 Antikörper) in cell cycle progression and Cyclin E expression in B lymphocytes, and suggest a potential function for NFAT1 (zeige NFAT1 Antikörper) protein in B cell malignancies.

Mouse (Murine) Cyclin E1 (CCNE1) Interaktionspartner

  1. These results demonstrate a repressor role for NFAT1 (zeige NFAT1 Antikörper) in cell cycle progression and Cyclin E expression in B lymphocytes, and suggest a potential function for NFAT1 (zeige NFAT1 Antikörper) protein in B cell malignancies.

  2. This approach allowed us to determine the identity of cyclin E protein partners, as well as phosphorylation substrates of cyclins E (cyclin (zeige PCNA Antikörper) E1and cyclin E2 (zeige CCNE2 Antikörper))and its associated kinase, Cdk2 (zeige CDK2 Antikörper), in different mouse organs.

  3. inhibition of PDK4 (zeige PDK4 Antikörper) activity in Hepatocellular carcinoma cells increased cyclin E1, cyclin A2 (zeige CCNA2 Antikörper), and E2F1 (zeige E2F1 Antikörper) proteins.

  4. Spermatocytes lacking cyclin E2 (zeige CCNE2 Antikörper) and one E1 allele (E1+/-E2-/-) displayed a high rate of telomere abnormalities but can progress to pachytene and diplotene stages.

  5. NF-kappaB (zeige NFKB1 Antikörper)-miR (zeige MLXIP Antikörper)-195/497-Igf1r (zeige IGF1R Antikörper)/Insr (zeige INSR Antikörper)-Ccnd2 (zeige CCND2 Antikörper)/Ccne1 plays important roles in myogenesis.

  6. Myb (zeige MYB Antikörper) regulates Cyclin E1 expression in normal gastrointestinal tract epithelial cells and is required during intestinal tumorigenesis

  7. These results highlight a new role for E-type cyclins (Ccne1 and Ccne2 (zeige CCNE2 Antikörper)) as important regulators of male meiosis.

  8. Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 (zeige CDK2 Antikörper) in hepatocytes inhibits DNA replication and liver regeneration in mice.

  9. Superoxide dismutase (zeige SOD1 Antikörper) induces G1-phase cell cycle arrest by down-regulated expression of Cdk-2 (zeige CDK2 Antikörper) and cyclin-E in sarcoma tumor cells.

  10. Ablation of cyclin E led to a decreased number of synapses, reduced number and volume of dendritic spines, and resulted in impaired synaptic plasticity and memory formation.

Xenopus laevis Cyclin E1 (CCNE1) Interaktionspartner

  1. miR (zeige MYLIP Antikörper)-15/16 and CPEB co-regulate cyclin E1 mRNA.

  2. cyclin E is dynamically and highly conjugated to SUMO2 (zeige SUMO2 Antikörper)/3 on chromatin, independently of Cdk2 (zeige CDK2 Antikörper) activity and origin activation.

  3. These results show that cyclin E destruction at the midblastula transition requires both phosphorylation and nuclear import, as well as proteasomal activity.

Zebrafish Cyclin E1 (CCNE1) Interaktionspartner

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (zeige CDK1 Antikörper), wee1 (zeige WEE1 Antikörper), p21 (zeige CDKN1A Antikörper), PCNA (zeige PCNA Antikörper) and cdk2 (zeige CDK2 Antikörper), but only weakly influences cyclin B1 (zeige CCNB1 Antikörper), cyclin B2 (zeige CCNB2 Antikörper) and cyclin E1 expression.

Cyclin E1 (CCNE1) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.

Alternative names and synonyms associated with Cyclin E1 (CCNE1)

  • cyclin E1 (CCNE1) Antikörper
  • cyclin E1 (ccne1) Antikörper
  • cyclin E1 (Ccne1) Antikörper
  • cyclin E1 (cycE1) Antikörper
  • AW538188 Antikörper
  • Ccne Antikörper
  • CCNE1 Antikörper
  • cyce Antikörper
  • CycE1 Antikörper
  • cyce2 Antikörper
  • cycE3 Antikörper
  • CYCLE Antikörper
  • cyclinE Antikörper
  • fa18e07 Antikörper
  • wu:fa18e07 Antikörper

Bezeichner auf Proteinebene für anti-Cyclin E1 (CCNE1) Antikörper

cyclin E1 , G1/S-specific cyclin-E1 , G1/S-specific cyclin-E1-like , g1/S-specific cyclin-E1-like , cyclin Es , cyclin Et , cyclin E , G1/S-specific cyclin-E2 , cyclin-E-1 , G1/S-specific cyclin-E3 , cyclin E3

GENE ID SPEZIES
455914 Pan troglodytes
484610 Canis lupus familiaris
533526 Bos taurus
549082 Xenopus (Silurana) tropicalis
700589 Macaca mulatta
100053882 Equus caballus
100396520 Callithrix jacchus
100461587 Pongo abelii
100471009 Ailuropoda melanoleuca
100523248 Sus scrofa
100607751 Nomascus leucogenys
898 Homo sapiens
12447 Mus musculus
25729 Rattus norvegicus
426117 Gallus gallus
397840 Xenopus laevis
397841 Xenopus laevis
30188 Danio rerio
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