anti-TCF4 (TCF4) Antikörper

Bezeichnung:
anti-Transcription Factor 4 Antikörper (TCF4)
Auf www.antikoerper-online.de finden Sie aktuell 86 Transcription Factor 4 (TCF4) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TCF4 Kits (10) und TCF4 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 111 TCF4 Produkte verfügbar.
Synonyme:
5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, GE2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, mTcf-4B, mTcf-4E, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, Tcf-4, Tcf4, TCF4B, TCF4E, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4

Meistgesuchte Reaktivitäten zu anti-TCF4 (TCF4) Antikörper

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anti-Human TCF4 Antikörper:

anti-Mouse (Murine) TCF4 Antikörper:

anti-Rat (Rattus) TCF4 Antikörper:

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Am meisten referenzierte anti-TCF4 Antikörper

  1. Human Monoclonal TCF4 Primary Antibody für IHC (p), IP - ABIN264393 : Barker, Huls, Korinek, Clevers: Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. in The American journal of pathology 1999 (PubMed)
    Zeige alle 5 Referenzen für 264393

  2. Human Monoclonal TCF4 Primary Antibody für IF, ELISA - ABIN520754 : Tanaka, Itoh, Nishiyama, Takezawa, Kurihara, Itoh, Kato: Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. in Blood 2010 (PubMed)
    Zeige alle 3 Referenzen für 520754

  3. Human Monoclonal TCF4 Primary Antibody für EMSA, IHC (p) - ABIN264394 : Denys, Jadidizadeh, Amini Nik, Van Dam, Aerts, Alman, Cassiman, Tejpar: Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. in Oncogene 2004 (PubMed)
    Zeige alle 2 Referenzen für 264394

  4. Human Polyclonal TCF4 Primary Antibody für IF, IP - ABIN318967 : Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006 (PubMed)

  5. Human Monoclonal TCF4 Primary Antibody für IF, WB - ABIN393964 : Eichhoff, Weeraratna, Zipser, Denat, Widmer, Xu, Kriegl, Kirchner, Larue, Dummer, Hoek: Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. in Pigment cell & melanoma research 2011 (PubMed)

  6. Guinea Pig Polyclonal TCF4 Primary Antibody für WB - ABIN2792580 : Raurell, Castaño, Francí, García de Herreros, Duñach: Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. Implications for the regulation of beta-catenin/Tcf-4-dependent transcription. in The Journal of biological chemistry 2006 (PubMed)

  7. Guinea Pig Polyclonal TCF4 Primary Antibody für WB - ABIN2792579 : Lu, Sheng, Mo, Li, Wu, Shen: A negative regulatory element-dependent inhibitory role of ITF2B on IL-2 receptor alpha gene. in Biochemical and biophysical research communications 2005 (PubMed)

Weitere Antikörper gegen TCF4 Interaktionspartner

Zebrafish Transcription Factor 4 (TCF4) Interaktionspartner

  1. GRG5/AES (zeige AES Antikörper) interacts with TCF4 (zeige TCF7L2 Antikörper) and represses Wnt (zeige WNT2 Antikörper)-mediated transcription both in human cells and zebrafish embryos.

Xenopus laevis Transcription Factor 4 (TCF4) Interaktionspartner

  1. Data indicte that Tcf-1 (zeige HNF1A Antikörper) and Lef-1 (zeige LEF1 Antikörper) exhibit a function in the axis induction assay, which is lacking in Tcf-3 (zeige TCF3 Antikörper) and -4.

  2. Tcf4 (zeige TCF7L2 Antikörper) transcription factor cooperates in patterning the Xenopus brain.

Human Transcription Factor 4 (TCF4) Interaktionspartner

  1. We found that the genotype "AG" of rs9320010 and "GA" of rs7235757 decreased SCZ risk. In the genetic model analysis, we also observed that the allele "A" of rs9320010 and "G" of rs7235757 were inversely related with the risk of SCZ in the dominant model. Our study indicated that rs9320010, rs7235757, and rs1452787 were prominently associated with SCZ.

  2. Our work suggests that DM1 (zeige DMPK Antikörper) patients are at risk for Fuchs' endothelial corneal dystrophy (FECD (zeige COL8a2 Antikörper)). DMPK (zeige DMPK Antikörper) mutations contribute to the genetic burden of FECD (zeige COL8a2 Antikörper) but are uncommon. We establish a connection between two repeat expansion disorders converging upon RNA-MBNL1 (zeige MBNL1 Antikörper) foci and FECD (zeige COL8a2 Antikörper).

  3. the variation of the TCF7L2 (zeige TCF7L2 Antikörper) gene in three Amerindian populations

  4. These data define the mechanism responsible for the repressive effects of nitric oxide (NO) on the transcriptional activity of beta-catenin (zeige CTNNB1 Antikörper) and link eNOS (zeige NOS3 Antikörper)-derived NO to the modulation by VEGF (zeige VEGFA Antikörper) of Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper)-induced endothelial cell proliferation.

  5. we show that TopoIIalpha forms protein-protein interactions with beta-catentin and TCF4 and interacts with Wnt (zeige WNT2 Antikörper) response elements (WREs) and promoters of direct target genes of TCF (zeige HNF4A Antikörper) transcription, including: MYC (zeige MYC Antikörper), vimentin (zeige VIM Antikörper), AXIN2 (zeige AXIN2 Antikörper) and LEF1 (zeige LEF1 Antikörper)

  6. novel TCF7L2 (zeige TCF7L2 Antikörper) type 2 diabetes SNP identified from fine mapping in African American women

  7. GWAS identified two known loci (TCF7L2 (zeige TCF7L2 Antikörper) and KCNQ1 (zeige KCNQ1 Antikörper)) reaching genome-wide significance levels in Hispanic type 2 diabetes patients.

  8. We demonstrate that expansion of the CTG18.1 trinucleotide repeat in TCF4 is associated with a higher risk of corneal transplantation at a younger age, assessed for the first time in a multiracial population sample with Fuchs corneal dystrophy from the United States.

  9. Nuclear TCF4/TCF7L2 expression affected the survival of patients with esophageal squamous cell carcinoma (ESCC). Positive expression of TCF4/TCF7L2 was correlated with a poor prognosis after a curative operation in patients with ESCC.

  10. The results provide a strong evidence for independent association between type 2 diabetes mellitus and SNPs for in TCF7L2 (zeige TCF7L2 Antikörper) and SLC30A8 (zeige SLC30A8 Antikörper).

Mouse (Murine) Transcription Factor 4 (TCF4) Interaktionspartner

  1. We report that TCF4 comprises two transcriptional isoforms, both of which are required for optimal plasmacytoid DC development in vitro

  2. these data identified E2A (zeige TCF3 Antikörper) and E2-2 as central regulators of B cell immunity.

  3. down-regulation of Id3 (zeige ID3 Antikörper) in B cells is essential for releasing E2A (zeige TCF3 Antikörper) and E2-2, which in a redundant manner are required for antigen-induced B cell differentiation.

  4. TCF7L2 (zeige TCF7L2 Antikörper) mediates canonic Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling and c-Myc (zeige MYC Antikörper) upregulation during abnormal cardiac remodeling in heart failure and suppression of Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) to c-Myc (zeige MYC Antikörper) axis can be explored for preventing and treating heart failure.

  5. TCF-4 as a co-activator of p65 (zeige NFkBP65 Antikörper) in the potentiation of proinflammatory cytokine production in macrophages and aggravation of high-fat diet induced chronic inflammation and insulin (zeige INS Antikörper) resistance in mice.

  6. These findings suggest a unique role for Tcf7l2 (zeige TCF7L2 Antikörper) in generating distinct neuronal phenotypes from homogeneous progenitor population.

  7. Tcf7l2 (zeige TCF7L2 Antikörper) may be involved in maintenance of stem/progenitor cells properties.

  8. Data indicate that upregulation of E2-2 protein markedly attenuated the inhibitor of DNA-binding 1 (ID1 (zeige ID1 Antikörper))-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.

  9. results indicate that miR (zeige MLXIP Antikörper)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) and Wnt (zeige WNT2 Antikörper) signaling pathway by directly targeting Smad7 (zeige SMAD7 Antikörper) and Tcf7l2 (zeige TCF7L2 Antikörper)

  10. Tcf7l2 (zeige TCF7L2 Antikörper) protein levels decline upon initiation of endocrine differentiation in vivo, disclosing the downregulation of this factor in the developing endocrine compartment.

TCF4 Antigen-Profil

Beschreibung des Gens

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF4

  • transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2) Antikörper
  • transcription factor 4 (tcf4) Antikörper
  • transcription factor 4 (TCF4) Antikörper
  • transcription factor 4 (Tcf4) Antikörper
  • transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2) Antikörper
  • transcription factor 7-like 2 (T-cell specific, HMG-box) (LOC396347) Antikörper
  • 5730422P05Rik Antikörper
  • ASP-I2 Antikörper
  • bHLHb19 Antikörper
  • E2-2 Antikörper
  • e2-A Antikörper
  • E2.2 Antikörper
  • GE2 Antikörper
  • ITF-2 Antikörper
  • ITF-2b Antikörper
  • ITF2 Antikörper
  • ME2 Antikörper
  • MITF-2A Antikörper
  • MITF-2B Antikörper
  • mTcf-4B Antikörper
  • mTcf-4E Antikörper
  • PTHS Antikörper
  • SEF-2 Antikörper
  • SEF2 Antikörper
  • SEF2-1 Antikörper
  • SEF2-1A Antikörper
  • SEF2-1B Antikörper
  • Tcf-4 Antikörper
  • Tcf4 Antikörper
  • TCF4B Antikörper
  • TCF4E Antikörper
  • TCF7L2 Antikörper
  • TFE Antikörper
  • XE2 Antikörper
  • Xtcf-4 Antikörper
  • Xtcf4 Antikörper

Bezeichner auf Proteinebene für TCF4

transcription factor 7-like 2 (T-cell specific, HMG-box) , transcription factor 4 , transcription factor 4-like , tcf4l , helix-loop-helix transcription factor , SL3-3 enhancer factor 2 , class B basic helix-loop-helix protein 19 , immunoglobulin transcription factor 2 , ITF-2 , TCF-4 , thyroglobulin promoter transcription factor TFE , transcriptional factor 4 , MITF-2 , Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2) , class A helix-loop-helix transcription factor ME2 , immunoglobulin transcription factor-2 , R8f DNA-binding protein , RITF-2 , SEF-2 , HMG box transcription factor 4 , T-cell factor 4 , T-cell-specific transcription factor 4 , mTCF-4 , transcription factor 7-like 2 , transcription factor 7-like 2, T-cell specific, HMG-box , transcription factor Tcf4 , T-cell factor-4 variant A , T-cell factor-4 variant B , T-cell factor-4 variant C , T-cell factor-4 variant D , T-cell factor-4 variant E , T-cell factor-4 variant F , T-cell factor-4 variant G , T-cell factor-4 variant H , T-cell factor-4 variant I , T-cell factor-4 variant J , T-cell factor-4 variant K , T-cell factor-4 variant L , T-cell factor-4 variant M , T-cell factor-4 variant X2 , hTCF-4

GENE ID SPEZIES
100049930 Equus caballus
100445658 Pongo abelii
100526651 Danio rerio
373726 Xenopus laevis
6925 Homo sapiens
403949 Canis lupus familiaris
534935 Bos taurus
21413 Mus musculus
84382 Rattus norvegicus
100511671 Sus scrofa
21416 Mus musculus
395508 Gallus gallus
6934 Homo sapiens
396347 Gallus gallus
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