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anti-Human TCF4 Antikörper:
anti-Mouse (Murine) TCF4 Antikörper:
anti-Rat (Rattus) TCF4 Antikörper:
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Human Monoclonal TCF4 Primary Antibody für IF, ELISA - ABIN520754
Tanaka, Itoh, Nishiyama, Takezawa, Kurihara, Itoh, Kato: Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. in Blood 2010
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Human Monoclonal TCF4 Primary Antibody für IHC (p), IP - ABIN264393
Barker, Huls, Korinek, Clevers: Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. in The American journal of pathology 1999
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Human Polyclonal TCF4 Primary Antibody für IHC, IHC (p) - ABIN4358095
Saegusa, Hashimura, Kuwata: Sox4 functions as a positive regulator of β-catenin signaling through upregulation of TCF4 during morular differentiation of endometrial carcinomas. in Laboratory investigation; a journal of technical methods and pathology 2012
Human Polyclonal TCF4 Primary Antibody für IF, IP - ABIN2476691
Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006
Human Monoclonal TCF4 Primary Antibody für IF, WB - ABIN393964
Eichhoff, Weeraratna, Zipser, Denat, Widmer, Xu, Kriegl, Kirchner, Larue, Dummer, Hoek: Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. in Pigment cell & melanoma research 2011
Human Monoclonal TCF4 Primary Antibody für EMSA, IHC (p) - ABIN264394
Denys, Jadidizadeh, Amini Nik, Van Dam, Aerts, Alman, Cassiman, Tejpar: Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. in Oncogene 2004
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GRG5/AES (zeige AES Antikörper) interacts with TCF4 (zeige TCF7L2 Antikörper) and represses Wnt (zeige WNT2 Antikörper)-mediated transcription both in human cells and zebrafish embryos.
Data indicte that Tcf-1 (zeige HNF1A Antikörper) and Lef-1 (zeige LEF1 Antikörper) exhibit a function in the axis induction assay, which is lacking in Tcf-3 (zeige TCF3 Antikörper) and -4.
Tcf4 (zeige TCF7L2 Antikörper) transcription factor cooperates in patterning the Xenopus brain.
repeat expansion showed stronger association than the most significantly associated SNP, rs613872, in TCF4, with the disease in the Australian cohort
Although validation in additional patients is required, the findings suggest that the dysmorphic features and severe intellectual disability characteristic of PTHS are partially rescued by overexpression of those short TCF4 transcripts encoding a nuclear localization signal, a transcription activation domain, and the basic helix-loop-helix domain.
these results indicate that targeting components of the PGC1alpha-ID2-TCF4-integrin signaling pathway may suppress melanoma metastasis, and suggest that early use of BRAFV600E inhibitors may have the potential to reduce metastasis.
The variant in TCF7L2 that increases fasting glucose levels increases between-subject variance, whereas variants in GCK and G6PC2 that increase fasting glucose levels decrease between-subject variance.
The rs7903146 (C/T) polymorphism of the TCF7L2 (zeige TCF7L2 Antikörper) gene might not be associated with obesity in the Cameroonian population.
These findings suggest that the rs7903146 locus might exert its enhancer function by interacting with HMGB1 (zeige HMGB1 Antikörper) in an allele dependent manner.
TCF7L2 (zeige TCF7L2 Antikörper) polymorphism is associated with colorectal cancer.
Data show that FERM domain-containing protein 5 (FRMD5) is regulated by both beta-catenin and transcription factor 7-Like 2 protein (TCF7L2) in colon cancer cells.
Altered DNA methylation (zeige HELLS Antikörper) in TCF4 involves in the etiology of Bipolar disorder and Major Depressive disorder .
We found that the genotype "AG" of rs9320010 and "GA" of rs7235757 decreased SCZ risk. In the genetic model analysis, we also observed that the allele "A" of rs9320010 and "G" of rs7235757 were inversely related with the risk of SCZ in the dominant model. Our study indicated that rs9320010, rs7235757, and rs1452787 were prominently associated with SCZ.
along with the elevation of miR-17-5p expression in mouse epididymal fat tissue in response to high fat diet consumption, allowed us to suggest that miR-17-5p is among central switches of adipogenic differentiation
We report that TCF4 comprises two transcriptional isoforms, both of which are required for optimal plasmacytoid DC development in vitro
these data identified E2A (zeige TCF3 Antikörper) and E2-2 as central regulators of B cell immunity.
down-regulation of Id3 (zeige ID3 Antikörper) in B cells is essential for releasing E2A (zeige TCF3 Antikörper) and E2-2, which in a redundant manner are required for antigen-induced B cell differentiation.
TCF7L2 (zeige TCF7L2 Antikörper) mediates canonic Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling and c-Myc (zeige MYC Antikörper) upregulation during abnormal cardiac remodeling in heart failure and suppression of Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) to c-Myc (zeige MYC Antikörper) axis can be explored for preventing and treating heart failure.
TCF-4 as a co-activator of p65 (zeige NFkBP65 Antikörper) in the potentiation of proinflammatory cytokine production in macrophages and aggravation of high-fat diet induced chronic inflammation and insulin (zeige INS Antikörper) resistance in mice.
These findings suggest a unique role for Tcf7l2 (zeige TCF7L2 Antikörper) in generating distinct neuronal phenotypes from homogeneous progenitor population.
Tcf7l2 (zeige TCF7L2 Antikörper) may be involved in maintenance of stem/progenitor cells properties.
Data indicate that upregulation of E2-2 protein markedly attenuated the inhibitor of DNA-binding 1 (ID1 (zeige ID1 Antikörper))-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.
results indicate that miR (zeige MLXIP Antikörper)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) and Wnt (zeige WNT2 Antikörper) signaling pathway by directly targeting Smad7 (zeige SMAD7 Antikörper) and Tcf7l2 (zeige TCF7L2 Antikörper)
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described.
SL3-3 enhancer factor 2
, class B basic helix-loop-helix protein 19
, immunoglobulin transcription factor 2
, Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2)
, class A helix-loop-helix transcription factor ME2
, immunoglobulin transcription factor-2
, R8f DNA-binding protein
, thyroglobulin promoter transcription factor TFE
, transcription factor 7-like 2 (T-cell specific, HMG-box)
, transcriptional factor 4
, helix-loop-helix transcription factor
, LOW QUALITY PROTEIN: transcription factor 4