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anti-TICAM2 (TICAM2) Antikörper

anti-Toll-Like Receptor Adaptor Molecule 2 Antikörper (TICAM2)
Auf finden Sie aktuell 112 Toll-Like Receptor Adaptor Molecule 2 (TICAM2) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TICAM2 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 140 TICAM2 Produkte verfügbar.
B430113A10, MyD88-4, TICAM-2, TIRAP3, Tirp, TRAM, Trif
Alle Antikörper anzeigen Gen GeneID UniProt
TICAM2 364867  
TICAM2 353376 Q86XR7
TICAM2 225471 Q8BJQ4

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TICAM2 (TICAM2) Antikörper

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anti-Rat (Rattus) TICAM2 Antikörper:

anti-Human TICAM2 Antikörper:

anti-Mouse (Murine) TICAM2 Antikörper:

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Am meisten referenzierte anti-TICAM2 Antikörper

  1. Human Monoclonal TICAM2 Primary Antibody für FACS - ABIN2665412 : Enokizono, Kumeta, Funami, Horiuchi, Sarmiento, Yamashita, Standley, Matsumoto, Seya, Inagaki: Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)
    Zeige alle 6 Referenzen für ABIN2665412

  2. Human Polyclonal TICAM2 Primary Antibody für EIA, IF - ABIN500929 : ONeill, Fitzgerald, Bowie: The Toll-IL-1 receptor adaptor family grows to five members. in Trends in immunology 2003 (PubMed)
    Zeige alle 4 Referenzen für ABIN500929

  3. Human Polyclonal TICAM2 Primary Antibody für DB, EIA - ABIN493396 : Oshiumi, Sasai, Shida, Fujita, Matsumoto, Seya: TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 3 Referenzen für ABIN493396

  4. Human Polyclonal TICAM2 Primary Antibody für DB, EIA - ABIN493528 : Oshiumi, Matsumoto, Funami, Akazawa, Seya: TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. in Nature immunology 2003 (PubMed)
    Zeige alle 3 Referenzen für ABIN493528

  5. Human Polyclonal TICAM2 Primary Antibody für IHC (fro), WB - ABIN265137 : Vogel, Fitzgerald, Fenton: TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. in Molecular interventions 2004 (PubMed)
    Zeige alle 2 Referenzen für ABIN265137

  6. Human Polyclonal TICAM2 Primary Antibody für WB - ABIN657981 : Lysakova-Devine, Keogh, Harrington, Nagpal, Halle, Golenbock, Monie, Bowie: Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

Weitere Antikörper gegen TICAM2 Interaktionspartner

Human Toll-Like Receptor Adaptor Molecule 2 (TICAM2) Interaktionspartner

  1. Data show that Toll (zeige TLR4 Antikörper)/IL-1R domain-containing adaptor molecule (TICAM)-2 possesses two conserved acidic amino acids, D91 and E92, which regulate TICAM-2 self-activation and signaling.

  2. Findings were SNPs in TICAM2 (P = 3.6 x 10(-6)) and IL1B (zeige IL1B Antikörper) (P = 4.3 x 10(-5)) associated with TB.

  3. TRAM (zeige TRAM1 Antikörper) plays a role in TLR7 (zeige TLR7 Antikörper) signaling through a novel signaling axis towards the activation of anti-viral immunity.

  4. TRAM (zeige TRAM1 Antikörper) acts as a sorting adaptor not only for TLR4 (zeige TLR4 Antikörper), but also for TLR2 (zeige TLR2 Antikörper), to facilitate signaling to IRF7 (zeige IRF7 Antikörper) at the endosome, which explains how TLR2 (zeige TLR2 Antikörper) is capable of causing type I IFN induction.

  5. A putative TRAF6 (zeige TRAF6 Antikörper)-binding motif in TRAM (zeige TRAM1 Antikörper) may mediate a new TRAM (zeige TRAM1 Antikörper) function in TLR4 (zeige TLR4 Antikörper) signaling in regulating inflammatory responses, distinct from its bridging TLR4 (zeige TLR4 Antikörper) and TRIF (zeige TRIM69 Antikörper). A TRAM (zeige TRAM1 Antikörper) E183A mutation abolished this.

  6. results suggest TLR adaptor molecules knockdown, such as MyD88 (zeige MYD88 Antikörper) or TRAM (zeige TRAM1 Antikörper), can decrease IL-6 (zeige IL6 Antikörper) and IL-8 (zeige IL8 Antikörper) mRNA and increase CXCL12 (zeige CXCL12 Antikörper) mRNA expression in HGF (zeige HGF Antikörper) and HPDLF.

  7. The homotypic interaction between TICAM-2 TIR is indispensable to present a scaffold for recruiting the monomeric moiety of the TICAM-1 (zeige TICAM1 Antikörper) TIR dimer.

  8. induction of both IL-6 (zeige IL6 Antikörper) and IL-8 (zeige IL8 Antikörper) is associated with elevated TIRAP (zeige TIRAP Antikörper) and reduced TRAM (zeige TRAM1 Antikörper) mRNA expression

  9. Data indicate that MyD88 (zeige MYD88 Antikörper) works together with the IL-1 (zeige IL1A Antikörper)/IL-18 (zeige IL18 Antikörper) receptors, can interact with two distinct sorting adaptors, TRAM (zeige TRAM1 Antikörper) and Mal (zeige MAL Antikörper), in a conserved manner.

  10. viral inhibitor peptide of TLR4 (zeige TLR4 Antikörper) possibly represents a surface domain of A46 that specifically inhibits TLR4 (zeige TLR4 Antikörper) by masking critical binding sites on MyD88 adaptor (zeige MYD88 Antikörper)-like and TRIF-related adaptor molecule

Mouse (Murine) Toll-Like Receptor Adaptor Molecule 2 (TICAM2) Interaktionspartner

  1. STING and TRIF (zeige RNF138 Antikörper) Contribute to Mouse Sepsis, Depending on Severity of the Disease Model

  2. the role of Toll (zeige TLR4 Antikörper)-like receptor (TLR) 2 (zeige TLR2 Antikörper), TLR4 (zeige TLR4 Antikörper), myeloid differentiation response gene 88, and Toll (zeige TLR4 Antikörper)-IL-1 (zeige IL1A Antikörper) receptor domain-containing adaptor-inducing interferon-gamma (zeige IFNG Antikörper) (TRIF (zeige RNF138 Antikörper)), factors critically involved in the TLR signaling pathway, was studied in experimental autoimmune neuritis.

  3. Juniperus rigida Sieb. extract inhibits macrophage inflammatory responses by attenuating TRIF (zeige RNF138 Antikörper)-dependent signaling and inflammasome activation.

  4. TRIF (zeige RNF138 Antikörper)-independent pathways can be involved in the downregulation of drug metabolizing enzymes and transporters through TLR4 (zeige TLR4 Antikörper) and 3. JNK (zeige MAPK8 Antikörper)-dependent mechanisms likely mediate this downregulation.

  5. Data show that annexin A2 (AnxA2 (zeige ANXA2 Antikörper)) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4 (zeige TLR4 Antikörper))-initiated TRAM protein (zeige TRAM2 Antikörper)-TRIF (zeige RNF138 Antikörper) protein pathway occurring on endosomes.

  6. TRIF (zeige RNF138 Antikörper) mediates antibacterial defense during Gram-negative pneumonia, at least in part, by inducing IFN-x03B3; at the primary site of infection.

  7. The authors confirmed that the protective effect of poly I:C against enteric infection of mice with Yersinia enterocolitica was dependent on TLR3 (zeige TLR3 Antikörper)-mediated TRIF (zeige RNF138 Antikörper) signaling by using TLR3 (zeige TLR3 Antikörper)-deficient mice.

  8. MMP-12 (zeige MMP12 Antikörper) up-regulation mediated by SARM (zeige SARM1 Antikörper)-TRIF (zeige RNF138 Antikörper) signaling pathway contributes to IFN-gamma (zeige IFNG Antikörper)-independent airway inflammation and AHR (zeige AHR Antikörper) post RSV infection in nude mice.

  9. HMGB1 (zeige HMGB1 Antikörper) and its downstream TLR4 (zeige TLR4 Antikörper)/Myd88 (zeige MYD88 Antikörper)/TRIF (zeige RNF138 Antikörper) signaling pathway play important roles in the mouse intestinal I/R injury.

  10. TLR4 (zeige TLR4 Antikörper), TRIF (zeige RNF138 Antikörper), and MyD88 (zeige MYD88 Antikörper) mediate the intraocular inflammatory response in endophthalmitis caused by Bacillus cereus.

TICAM2 Antigen-Profil

Beschreibung des Gens

TIRP is a Toll/interleukin-1 receptor (IL1R\; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4\; MIM 603030).

Alternative names and synonyms associated with TICAM2

  • toll-like receptor adaptor molecule 2 (Ticam2) Antikörper
  • toll-like receptor adaptor molecule 2 (TICAM2) Antikörper
  • B430113A10 Antikörper
  • MyD88-4 Antikörper
  • TICAM-2 Antikörper
  • TIRAP3 Antikörper
  • Tirp Antikörper
  • TRAM Antikörper
  • Trif Antikörper

Bezeichner auf Proteinebene für TICAM2

TIR domain-containing adapter molecule 2 , TMED7-TICAM2 readthrough , NF-kappa-B-activating protein 502 , TRIF-related adaptor molecule , cytoplasmic adaptor , putative NF-kappa-B-activating protein 502 , toll-like receptor adaptor protein 3 , toll/interleukin-1 receptor (TIR) domain-containing adapter protein , TIR domain-containing adapter protein , TRIF-related adapter molecule TRAM , Toll-interleukin I receptor domain (TIR)-containing adaptor molecule (TICAM) 2 , toll/interleukin-1 receptor domain-containing protein , TRIF-related adapter molecule

364867 Rattus norvegicus
100029323 Monodelphis domestica
100409449 Callithrix jacchus
100500706 Pan troglodytes
100520421 Sus scrofa
100529854 Equus caballus
100533188 Canis lupus familiaris
353376 Homo sapiens
225471 Mus musculus
539350 Bos taurus
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