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Navigieren Sie durch unsere anti-LY96 (LY96) Antikörper

Full name:
anti-Lymphocyte Antigen 96 Antikörper (LY96)
Auf finden Sie aktuell 111 Lymphocyte Antigen 96 (LY96) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LY96 Kits (17) und LY96 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 150 LY96 Produkte verfügbar.
ESOP-1, Ly-96, MD-2, Md2

Meistgesuchte Reaktivitäten zu anti-LY96 (LY96) Antikörper

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anti-Human LY96 Antikörper:

anti-Mouse (Murine) LY96 Antikörper:

anti-Rat (Rattus) LY96 Antikörper:

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Am meisten referenzierte anti-LY96 Antikörper

  1. Human Monoclonal LY96 Primary Antibody für Func - ABIN1108191 : Pugin, Stern-Voeffray, Daubeuf, Matthay, Elson, Dunn-Siegrist: Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock. in Blood 2004 (PubMed)
    Zeige alle 4 Referenzen für ABIN1108191

  2. Human Polyclonal LY96 Primary Antibody für IHC (p), IHC - ABIN252602 : Kunda, Cavicchia, Acosta: Lipopolysaccharides and trophic factors regulate the LPS receptor complex in nodose and trigeminal neurons. in Neuroscience 2014 (PubMed)
    Zeige alle 3 Referenzen für ABIN252602

  3. Human Polyclonal LY96 Primary Antibody für EIA, IF - ABIN500262 : ONeill, Fitzgerald, Bowie: The Toll-IL-1 receptor adaptor family grows to five members. in Trends in immunology 2003 (PubMed)
    Zeige alle 2 Referenzen für ABIN500262

  4. Human Monoclonal LY96 Primary Antibody für Func, EIA - ABIN1108192 : Viriyakosol, McCray, Ashbaugh, Chu, Jia, Weiss, Kirkland: Characterization of monoclonal antibodies to human soluble MD-2 protein. in Hybridoma (2005) 2007 (PubMed)

Weitere Antikörper gegen LY96 Interaktionspartner

Human Lymphocyte Antigen 96 (LY96) Interaktionspartner

  1. In this study, a novel naturally occurring spliceosome of human MD2, termed as MD2-T3, has been identified.

  2. Results show that cigarette smoke may alter innate immune responses reducing the expression of the MD2, a molecule with an important role in TLR4 (zeige TLR4 Antikörper) signaling.

  3. Predominantly hydrophobic interactions between MD-2 and TLR4 (zeige TLR4 Antikörper) contribute to the stabilization of the TLR4 (zeige TLR4 Antikörper)/MD-2/metal ion complex in a conformation that enables activation.

  4. The intensity of the intra-amniotic inflammatory response to bacteria or perhaps to other TLR4 (zeige TLR4 Antikörper) ligands may be facilitated through synthesis and release of sMD2 (zeige SNRPD2 Antikörper) by the amniochorion.

  5. Three genes (LY96, IL8 (zeige IL8 Antikörper) DPR (zeige DACT1 Antikörper)) were significantly downregulated over time. This finding was confirmed in a validation cohort of stroke patients (n=8).

  6. The study revealed the impact of specific residues and regions of MD-2 on the binding of lipolysaccharides and TLR4 (zeige TLR4 Antikörper).

  7. Gene polymorphisms of MD2 and GM2A (zeige GM2A Antikörper) were associated with the occurrence or severity of neonatal necrotizing enterocolitis.

  8. In patients undergoing CABG surgery, we found genetic polymorphisms in LY96 associated with decreased risk of postoperative AF.

  9. Aminoarabinose residues in lipid A contribute to Burkholderia lipid A binding to the TLR4 (zeige TLR4 Antikörper).Myeloid Differentiation Factor 2 complex.

  10. TLR4 (zeige TLR4 Antikörper) along with its accessory protein MD-2 builds a heterodimeric complex that specifically recognizes lipopolysaccharides, which are present on the cell wall of gram-negative bacteria, activating the immune response. (Review)

Mouse (Murine) Lymphocyte Antigen 96 (LY96) Interaktionspartner

  1. Neoseptin-3 and lipid A form dissimilar molecular contacts to achieve receptor activation; hence strong TLR4 (zeige TLR4 Antikörper)/MD-2 agonists need not mimic LPS (zeige TLR4 Antikörper)

  2. Here we demonstrate that cholesterol binds to myeloid differentiation-2 (MD-2), a TLR4 (zeige TLR4 Antikörper) ancillary molecule.

  3. MD-2 is a critical regulator of the establishment of allergic airway sensitization to HDM (zeige HDAC3 Antikörper) in mice. Serum MD-2 may represent a potential biomarker for the amplification of allergic sensitization and allergic inflammation.

  4. Data show that myeloid differentiation factor 2 (MD-2) binds specifically to disulfide isoform of box protein 1, high mobility group (zeige SSRP1 Antikörper) (HMGB1 (zeige HMGB1 Antikörper)) to facilitate toll-like receptor 4 (TLR4 (zeige TLR4 Antikörper))-dependent signaling.

  5. Carbon monoxide treatment reduces the expression of the TLR4 (zeige TLR4 Antikörper)/MD2 complex on the surface of myeloid cells, which renders them resistant to lipopolysaccharide priming in vitro, as well as in vivo in a model of endotoxic shock.

  6. Mechanistically, engagement of MD-2 by PTX3 (zeige PITX3 Antikörper)-opsonized Aspergillus conidia activated the TLR4/Toll (zeige TLR4 Antikörper)/IL-1R domain-containing adapter inducing IFN-beta (zeige IFNB1 Antikörper)-dependent signaling pathway converging on IL-10 (zeige IL10 Antikörper).

  7. SAA3 directly binds MD-2 and activates the MyD88 (zeige MYD88 Antikörper)-dependent TLR4 (zeige TLR4 Antikörper)/MD-2 pathway.

  8. Monophosphoryl lipid A is unable to efficiently form TLR4 (zeige TLR4 Antikörper)/MD-2 heterotetramers, but it still needs heterotetramer formation for the full extent of signaling it is able to achieve.

  9. Data show that rifampin binds to myeloid differentiation protein 2 (MD-2), the key coreceptor for innate immune TLR4 (zeige TLR4 Antikörper).

  10. Gb4 is an endogenous ligand for TLR4 (zeige TLR4 Antikörper)-MD-2 and is capable of attenuating LPS (zeige TLR4 Antikörper) toxicity, indicating the possibility for its therapeutic application in endotoxin shock.

LY96 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with LY96

  • lymphocyte antigen 96 (LY96) Antikörper
  • lymphocyte antigen 96 (Ly96) Antikörper
  • ESOP-1 Antikörper
  • Ly-96 Antikörper
  • MD-2 Antikörper
  • Md2 Antikörper

Bezeichner auf Proteinebene für LY96

myeloid differentiation protein-2 , protein MD-2 , ly-96 , myeloid differentiation factor-2 , LPS co-receptor MD-2 , lymphocyte antigen 96 , MD-2 , Protein MD-2

696778 Macaca mulatta
23643 Homo sapiens
17087 Mus musculus
448830 Rattus norvegicus
613753 Bos taurus
610524 Canis lupus familiaris
420189 Gallus gallus
100729146 Cavia porcellus
100125555 Sus scrofa
100009589 Oryctolagus cuniculus
101108235 Ovis aries
100689342 Cricetulus griseus
Ausgewählte Anbieter für anti-LY96 (LY96) Antikörper
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