anti-NMDAR2A (GRIN2A) Antikörper

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a Antikörper (GRIN2A)
Auf finden Sie aktuell 238 Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NMDAR2A Kits (28) und NMDAR2A Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 280 NMDAR2A Produkte verfügbar.

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anti-Human NMDAR2A Antikörper:

anti-Rat (Rattus) NMDAR2A Antikörper:

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Am meisten referenzierte anti-NMDAR2A Antikörper

  1. Human Polyclonal NMDAR2A Primary Antibody für EIA, FACS - ABIN953719 : Endele, Rosenberger, Geider, Popp, Tamer, Stefanova, Milh, Kortüm, Fritsch, Pientka, Hellenbroich, Kalscheuer, Kohlhase, Moog, Rappold, Rauch, Ropers, von Spiczak, Tönnies, Villeneuve, Villard, Zabel, Zenker, Laube, Reis, Wieczorek, Van Maldergem, Kutsche: Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes. in Nature genetics 2010 (PubMed)
    Zeige alle 5 Referenzen für 953719

  2. Human Polyclonal NMDAR2A Primary Antibody für EIA, IHC (p) - ABIN953720 : King, Eugenin, Hazleton, Morgello, Berman: Mechanisms of HIV-tat-induced phosphorylation of N-methyl-D-aspartate receptor subunit 2A in human primary neurons: implications for neuroAIDS pathogenesis. in The American journal of pathology 2010 (PubMed)
    Zeige alle 5 Referenzen für 953720

  3. Human Polyclonal NMDAR2A Primary Antibody für IF (p), IHC (p) - ABIN747353 : Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014 (PubMed)
    Zeige alle 2 Referenzen für 747353

  4. Mouse (Murine) Monoclonal NMDAR2A Primary Antibody für IF, WB - ABIN968802 : Ishii, Moriyoshi, Sugihara, Sakurada, Kadotani, Yokoi, Akazawa, Shigemoto, Mizuno, Masu: Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. in The Journal of biological chemistry 1993 (PubMed)
    Zeige alle 2 Referenzen für 968802

  5. Human Monoclonal NMDAR2A Primary Antibody für ICC, IF - ABIN2483897 : Teng, Cai, Zhou, Zhang, Liu, Wang, Dai, Zhao, Sun: Evolutionary mode and functional divergence of vertebrate NMDA receptor subunit 2 genes. in PLoS ONE 2010 (PubMed)

  6. Cow (Bovine) Polyclonal NMDAR2A Primary Antibody für IHC, WB - ABIN2776120 : Kim, Chang, Nagpal, Yamashita, Baek, Dasgupta, Wu, Osada, Woo, Westra, Trink, Ratovitski, Moon, Sidransky: The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth. in Oncogene 2008 (PubMed)

  7. Rat (Rattus) NMDAR2A Primary Antibody für ELISA, WB - ABIN1742591 : Wang, Liu, Fu, Wang, Lu: Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. in Nature neuroscience 2003 (PubMed)

Weitere Antikörper gegen NMDAR2A Interaktionspartner

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Interaktionspartner

  1. 2-methoxyestradiol impacts on glycine/serine-mediated metabolic reprogramming in osteosarcoma cells by its interaction with GRIN1 (zeige GRIN1 Antikörper)/GluN2A receptors.

  2. a de novo missense mutation in the GRIN2A gene in a patient with childhood focal epilepsy and acquired epileptic aphasia. The mutant decreases NMDAR (zeige GRIN1 Antikörper) activation suggesting NMDAR (zeige GRIN1 Antikörper) hypofunction may contribute to the epilepsy pathogenesis.

  3. genetic association studies in population in China: Data suggest that one SNP in GRIN2A (rs2650429; but not rs6497540 or rs9302415) is associated with lead-induced neurotoxicity; in this case-control study, cases were lead-exposed workers from battery plants. Lead-exposed individuals have lower serum GRIN2A levels compared with controls; lead decreases GRIN2A expression levels in HEK293 cell.

  4. Two adjacent phenylalanines in the NMDA receptor GluN2A subunit M3 domain interactively regulate alcohol sensitivity and ion channel gating.

  5. The GRIN2A genotype was not associated with the rate of clinical progression of PD in the placebo group.

  6. most rare variants in GluN2A were associated with epilepsy, whereas GluN2B (zeige GRIN2B Antikörper) variants were associated with intellectual disability with or without seizures

  7. the gain-of-function M817V mutation causes overactivation of NMDAR (zeige GRIN1 Antikörper) and drives neuronal hyperexcitability.

  8. To determine genetic variability within the N-methyl-D-aspartate receptor 2A sub-unit (GRIN2A) gene promoter and its association with concussion recovery time.

  9. Knockdown of PKD1 (zeige PKD1 Antikörper) did not affect NMDAR (zeige GRIN1 Antikörper) internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR (zeige GRIN1 Antikörper)-mediated synaptic functions.

  10. Findings suggest that mutations in GRIN2A preferentially are involved in genetic variance of pediatric idiopathic generalized epilepsy and do not contribute significantly to either adult focal epilepsies as temporal lobe epilepsy or generalized epilepsies

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Interaktionspartner

  1. This study demonstrated that Increasing the GluN2A/GluN2B (zeige GRIN2B Antikörper) Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

  2. Grin2aPKC mice exhibit reduced anxiety in the open field test, light dark emergence test, and elevated plus maze. Overall, these results suggest that at least one of those PKC (zeige PKC Antikörper)-mediated phosphorylation sites regulates NMDAR (zeige GRIN1 Antikörper)-mediated signaling that modulates anxiety.

  3. These data suggest that chronic early postnatal SSS influences spatial learning and memory ability, levels of hippocampal NR2B (zeige GRIN2B Antikörper), and NR2A/NR2B (zeige GRIN2B Antikörper) ratios in adult males.

  4. Rph3A (zeige RPH3A Antikörper) interacts with GluN2A and PSD-95 (zeige DLG4 Antikörper) forming a complex that regulates NMDARs stabilization at postsynaptic membranes.

  5. Egr-1 (zeige EGR1 Antikörper) is involved in NMDAR (zeige GRIN1 Antikörper)-mediated PSD-95 (zeige DLG4 Antikörper) down-regulation and AMPAR endocytosis, a process important in the expression of long term depression

  6. Study demonstrated that GluN2A carboxy-terminal domain is responsible for the impaired long-term olfactory and social memory observed in the GluN2A overexpression mice

  7. Results establish the GluN2A subunit as a significant contributor to both bidirectional synaptic plasticity and spatial pattern separation in the dentate gyrus

  8. Best1 (zeige BEST1 Antikörper)-mediated astrocytic glutamate (zeige GRIN1 Antikörper) activates the synaptic N-methyl-D-aspartate receptor (zeige GRIN1 Antikörper) (NMDAR (zeige GRIN1 Antikörper)) and modulates NMDAR (zeige GRIN1 Antikörper)-dependent synaptic plasticity.

  9. Data suggest a role for GluN2A in ethanol tolerance.

  10. We conclude that TSPYL2 (zeige TSPYL2 Antikörper) contributes to cognitive variability through regulating the expression of Grin2a and Grin2b (zeige GRIN2B Antikörper).

NMDAR2A (GRIN2A) Antigen-Profil

Beschreibung des Gens

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NMDAR2A (GRIN2A)

  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A) Antikörper
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A (grin2a) Antikörper
  • glutamate receptor ionotropic, NMDA 2A-like (LOC524212) Antikörper
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A (Grin2a) Antikörper
  • glutamate receptor, ionotropic, NMDA2A (epsilon 1) (Grin2a) Antikörper
  • EPND Antikörper
  • GluN2A Antikörper
  • GRIN2A Antikörper
  • NMDAR2A Antikörper
  • NR2A Antikörper

Bezeichner auf Proteinebene für GRIN2A

N-methyl-D-aspartate receptor subunit NR2A , glutamate receptor, ionotropic, N-methyl D-aspartate 2A , glutamate [NMDA] receptor subunit epsilon-1-like , N-methyl D-aspartate receptor subtype 2A , N-methyl-D-aspartate receptor channel, subunit epsilon-1 , N-methyl-D-aspartate receptor subunit 2A , NMDA receptor subtype 2A , glutamate [NMDA] receptor subunit epsilon-1 , glutamate receptor ionotropic, NMDA 2A , hNR2A , glutamate [NMDA] receptor subunit epsilon 1 , glutamate receptor, ionotropic, N-methyl-D-aspartate subunit 2A , GluRepsilon1

778440 Taeniopygia guttata
100127346 Xenopus laevis
100411569 Callithrix jacchus
100438553 Pongo abelii
100584731 Nomascus leucogenys
524212 Bos taurus
2903 Homo sapiens
24409 Rattus norvegicus
100727265 Cavia porcellus
490012 Canis lupus familiaris
427678 Gallus gallus
454396 Pan troglodytes
14811 Mus musculus
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