Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human COMT Antikörper:
anti-Mouse (Murine) COMT Antikörper:
anti-Rat (Rattus) COMT Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Monoclonal COMT Primary Antibody für WB - ABIN1882224
Zeng, Ye, Lu, Chua, Tan, Zhong: Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes. in Organic letters 2010
Show all 5 Pubmed References
Mouse (Murine) Monoclonal COMT Primary Antibody für BI, IF - ABIN968704
Gogos, Morgan, Luine, Santha, Ogawa, Pfaff, Karayiorgou: Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. in Proceedings of the National Academy of Sciences of the United States of America 1998
Show all 3 Pubmed References
Human Polyclonal COMT Primary Antibody für ELISA, WB - ABIN250484
Yao, Harris, Zhang: Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway. in Hypertension (Dallas, Tex. : 1979) 2009
Show all 3 Pubmed References
Human Polyclonal COMT Primary Antibody für IHC, IHC (p) - ABIN4299996
Hirata, Hinoda, Okayama, Suehiro, Kawamoto, Kikuno, Rabban, Chen, Dahiya: COMT polymorphisms affecting protein expression are risk factors for endometrial cancer. in Molecular carcinogenesis 2008
Human Polyclonal COMT Primary Antibody für EIA, ELISA - ABIN188559
Tunbridge, Harrison, Weinberger: Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond. in Biological psychiatry 2006
Human Polyclonal COMT Primary Antibody für WB - ABIN514522
Hevir, Sinkovec, Rižner: Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT. in Molecular and cellular endocrinology 2010
This study demonstrates the contribution of the COMT Val158Met polymorphism to individual differences in well-being and suggests a potential psychobiological pathway from dopaminergic and noradrenergic systems to happiness.
The KCNJ6 (zeige KCNJ6 Antikörper) -1250A and COMT Val alleles are predisposing preterm newborns to diminished opioid-induced pain relief.
found differences in Neonatal Abstinence Syndrome outcomes depending on PNOC (zeige PNOC Antikörper) and COMT SNP genotype.
The present findings suggest that COMT Val(108/158)Met polymorphism may not contribute to the risk of schizophrenia and to the P50 sernsory gating deficits, but may contribute to the negative symptoms of schizophrenia among Han Chinese.
COMT allelic risk may play a role in predicting cognitive change.
Study associates polymorphisms in DRD2 (zeige DRD2 Antikörper), DARPP-32 (zeige PPP1R1B Antikörper), and COMT genes with novel category learning performance. Modeling results suggest that striatal dopaminergic genes influence selective attention processes whereas cortical genes mediate the ability to update complex rule representations.
This study demonstrates that OPRM1 (zeige OPRM1 Antikörper) 118A>G and the combined OPRM1 (zeige OPRM1 Antikörper)/COMT genotype are associated with experimental thermal pain sensitivity in a paediatric population.
These data indicate a significant interaction between peripheral proline and COMT genotype, influencing negative symptoms in schizophrenia and bipolar disorder.
159 patients with 22q11.2 Deletion Syndrome (22q11DS) were analyzed for a potential association between intelligence quotient (IQ) and COMT genotype; no correlation between COMT genotype and IQ performance was found
Study provides support for the argument that Apolipoprotein E (APOE (zeige APOE Antikörper) varepsilon4+) and catechol-O-methyl transferase Met/Met genotypes can be used as predictors of faster cognitive decline in Parkinson's disease.
Miroestrol restored uterine COMT expression in beta-naphthoflavone-treated mice.
This study report that genetically driven reduction in COMT enzyme activity increased cortical thickness in the prefrontal cortex (PFC (zeige CFP Antikörper)) and postero-parieto-temporal cortex of male, but not female adult mice.
COMT expression in the hippocampus was significantly reduced by high E2 replacement, implying increased catecholamine levels in the hippocampus of high E2 mice.
COMT overexpressing mice display an increase in dopamine release capacity in the striatum, suggesting increased COMT activity may affect dopamine signaling by enhancing synaptic clearance in the cortex and changes in striatal presynaptic dopamine function
These data confirm at the level of mouse working memory and human working memory-associated physiology a genetic interaction between COMT and DTNBP1 (zeige DTNBP1 Antikörper).
The results of this study suggest that individual differences in COMT activity do not affect primary reinforcing effects of cocaine in mice.
Inhibition of COMT via serotonin binding contributes to pain hypersensitivity.
COMT knockout mice were more impulsive compared with wild-type littermates.
Data show that in male catechol-O-methyltransferase COMT(-/-)-mice, the total number of T-, and B-lymphocytes from spleen increased but the T-cell proliferative response decreased.
decreased COMT activity was associated with some changes in feeding microstructure in rats and mice
An analysis of polymorphisms of the COMT gene as a preliminary step in evaluating the role of the gene in behavior is reported.
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
, catechol-O-methyltransferase 1
, catechol O-methyltransferase, soluble form
, catechol O-methyltransferase, membrane-bound form