anti-COMT (COMT) Antikörper

anti-Catechol-O-Methyltransferase Antikörper (COMT)
Auf finden Sie aktuell 180 Catechol-O-Methyltransferase (COMT) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen COMT Kits (39) und COMT Proteine (27) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 258 COMT Produkte verfügbar.
comt, Comt1, D16Wsu103e, D330014B15Rik, mb-comt, MGC154444, s-comt

Meistgesuchte Reaktivitäten zu anti-COMT (COMT) Antikörper

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anti-Human COMT Antikörper:

anti-Mouse (Murine) COMT Antikörper:

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Am meisten referenzierte anti-COMT Antikörper

  1. Human Polyclonal COMT Primary Antibody für ELISA, WB - ABIN185328 : Tunbridge, Harrison, Weinberger: Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond. in Biological psychiatry 2006 (PubMed)
    Zeige alle 5 Referenzen für 185328

  2. Human Monoclonal COMT Primary Antibody für WB - ABIN393532 : Bodenmann, Landolt: Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT. in Sleep 2010 (PubMed)
    Zeige alle 5 Referenzen für 393532

  3. Human Monoclonal COMT Primary Antibody für WB - ABIN1882224 : Zeng, Ye, Lu, Chua, Tan, Zhong: Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes. in Organic letters 2010 (PubMed)
    Zeige alle 5 Referenzen für 1882224

  4. Mouse (Murine) Monoclonal COMT Primary Antibody für BI, IF - ABIN968704 : Gogos, Morgan, Luine, Santha, Ogawa, Pfaff, Karayiorgou: Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Zeige alle 3 Referenzen für 968704

  5. Cow (Bovine) Polyclonal COMT Primary Antibody für WB - ABIN2781821 : Shiels, Huang, Hoffman, Shugart, Bolton, Platz, Helzlsouer, Alberg: A community-based study of cigarette smoking behavior in relation to variation in three genes involved in dopamine metabolism: Catechol-O-methyltransferase (COMT), dopamine beta-hydroxylase (DBH) and monoamine oxidase-A (MAO-A). in Preventive medicine 2008 (PubMed)

Weitere Antikörper gegen COMT Interaktionspartner

Horse (Equine) Catechol-O-Methyltransferase (COMT) Interaktionspartner

  1. An analysis of polymorphisms of the COMT gene as a preliminary step in evaluating the role of the gene in behavior is reported.

Human Catechol-O-Methyltransferase (COMT) Interaktionspartner

  1. Association between COMT genotype and 6-m walk time: Those with higher (Val/Val) and lower (Met/Met) dopamine slowed more over 10 years than those with the intermediate (Met/Val) dopamine. Race differences seen.

  2. This paired case-control study examined the association between COMT gene rs4680 polymorphism and suicide attempts. The G/G genotype was significantly more prevalent in female suicide attempters than their matched controls. Conditional logistic regression showed that the G/G genotype was significantly associated with an increased risk of suicide attempts only for women (odds ratio=2.3; 95% confidence interval: 1.2-4.2)

  3. We report that the variation in gene sequence at the four COMT SNPs studied was not associated with an altered the risk of schizophrenia but genotype at rs4680 and rs4818, but not rs165519 and rs737865, were associated with varying levels of cortical CHRM1 (zeige CHRM1 Antikörper) expression in the human dorsolateral prefrontal cortex. These data are the first to suggest that levels of CHRM1 (zeige CHRM1 Antikörper) in the human DLPFC are, in part, determined by COMT seq

  4. Study is the first to demonstrate the influence of a functional and behaviorally relevant genetic variant (val158 met polymorphism on the catechol-O-methyltransferase gene) on connectome-wide functional connectivity and is an important step toward establishing the functional connectome as an endophenotype for psychiatric and behavioral phenotypes.

  5. This study found a significant interaction between rs4680 in COMT and rs4986936 in ESR1 (zeige ESR1 Antikörper) (P = .007) on opioid consumption.

  6. No direct correlation between catechol-O-methyltransferase (COMT) activity and rs4680 genotypes was found in patients with bipolar disorder; however, the severity of manic symptoms was highly correlated with COMT activity in the striatum, irrespective of the diagnostic group.

  7. The COMT Val158Met polymorphism was genotyped in a Swedish population-based cohort including 1,783 individuals, ages 20-24 years (47% males). A significant three-way interaction was found, after correction for multiple testing, between COMT genotype, exposure to violence, and parent-child relationship in association with physical but not verbal aggressive behavior.

  8. We found statistically significant DNA hypomethylation of the promoter regions of DRD3 (zeige DRD3 Antikörper) (P = 0.032), DRD4 (zeige DRD4 Antikörper) (P = 0.05), MB-COMT (P = 0.009), and AKT1 (zeige AKT1 Antikörper) (P = 0.0008) associated with increased expression of the corresponding genes in patients with methamphetamine psychosis (P = 0.022, P = 0.034, P = 0.035, P = 0.038, respectively)

  9. Bipolar patients: haplotypes of COMT are associated with age at onset and clinical evolution

  10. Lower catechol-O-methyltransferase (COMT) enzymatic activity decreases the clearance of dopamine (DA), yielding higher levels of catecholamines in the central nervous system. COMT haploinsufficiency, DA dysfunction, and white matter abnormalities may contribute toward the presence of neurological soft signs in 22q11DS. [review]

Mouse (Murine) Catechol-O-Methyltransferase (COMT) Interaktionspartner

  1. Miroestrol restored uterine COMT expression in beta-naphthoflavone-treated mice.

  2. This study report that genetically driven reduction in COMT enzyme activity increased cortical thickness in the prefrontal cortex (PFC (zeige CFP Antikörper)) and postero-parieto-temporal cortex of male, but not female adult mice.

  3. COMT expression in the hippocampus was significantly reduced by high E2 replacement, implying increased catecholamine levels in the hippocampus of high E2 mice.

  4. COMT overexpressing mice display an increase in dopamine release capacity in the striatum, suggesting increased COMT activity may affect dopamine signaling by enhancing synaptic clearance in the cortex and changes in striatal presynaptic dopamine function

  5. These data confirm at the level of mouse working memory and human working memory-associated physiology a genetic interaction between COMT and DTNBP1 (zeige DTNBP1 Antikörper).

  6. The results of this study suggest that individual differences in COMT activity do not affect primary reinforcing effects of cocaine in mice.

  7. Inhibition of COMT via serotonin binding contributes to pain hypersensitivity.

  8. COMT knockout mice were more impulsive compared with wild-type littermates.

  9. Data show that in male catechol-O-methyltransferase COMT(-/-)-mice, the total number of T-, and B-lymphocytes from spleen increased but the T-cell proliferative response decreased.

  10. decreased COMT activity was associated with some changes in feeding microstructure in rats and mice

COMT Antigen-Profil

Beschreibung des Gens

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

Alternative names and synonyms associated with COMT

  • catechol-O-methyltransferase (COMT) Antikörper
  • catechol-O-methyltransferase (comt) Antikörper
  • catechol-O-methyltransferase (comt.2) Antikörper
  • catechol-o-methyltransferase (Rv1703c) Antikörper
  • catechol-o-methyltransferase (Mb1729c) Antikörper
  • catechol O-methyltransferase-like (LOC100630273) Antikörper
  • catechol-O-methyltransferase (Comt) Antikörper
  • comt Antikörper
  • Comt1 Antikörper
  • D16Wsu103e Antikörper
  • D330014B15Rik Antikörper
  • mb-comt Antikörper
  • MGC154444 Antikörper
  • s-comt Antikörper

Bezeichner auf Proteinebene für COMT

catechol-O-methyltransferase , catechol-o-methyltransferase , catechol O-methyltransferase, soluble form , catechol O-methyltransferase, membrane-bound form , catechol O-methyltransferase , O-methyltransferase , catechol-O-methyltransferase 1 , catecholamine-O-methyltransferase

416783 Gallus gallus
458655 Pan troglodytes
549111 Xenopus (Silurana) tropicalis
549911 Xenopus (Silurana) tropicalis
779254 Xenopus laevis
885066 Mycobacterium tuberculosis H37Rv
1092683 Mycobacterium bovis AF2122/97
100033869 Equus caballus
100146509 Equus caballus
100630273 Equus caballus
1312 Homo sapiens
445450 Canis lupus familiaris
12846 Mus musculus
24267 Rattus norvegicus
618278 Bos taurus
100155530 Sus scrofa
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