anti-PRDM16 (PRDM16) Antikörper

Bezeichnung:
anti-PR Domain Containing 16 Antikörper (PRDM16)
Auf www.antikoerper-online.de finden Sie aktuell 69 PR Domain Containing 16 (PRDM16) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PRDM16 Proteine (11) und PRDM16 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 85 PRDM16 Produkte verfügbar.
Synonyme:
5730557K01Rik, C130091E20, csp1, mel1, mKIAA1675, PFM13, PRDM16, wu:fc09g08
Alle Antikörper anzeigen Gen GeneID UniProt
PRDM16 63976 Q9HAZ2
PRDM16 70673 A2A935
PRDM16 100366024  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-PRDM16 (PRDM16) Antikörper

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anti-Human PRDM16 Antikörper:

anti-Mouse (Murine) PRDM16 Antikörper:

anti-Rat (Rattus) PRDM16 Antikörper:

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Am meisten referenzierte anti-PRDM16 Antikörper

  1. Human Polyclonal PRDM16 Primary Antibody für ELISA - ABIN249627 : Stanford, Middelbeek, Townsend, An, Nygaard, Hitchcox, Markan, Nakano, Hirshman, Tseng, Goodyear: Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. in The Journal of clinical investigation 2013 (PubMed)
    Zeige alle 2 Referenzen für 249627

  2. Human Polyclonal PRDM16 Primary Antibody für ELISA, ICC - ABIN4347210 : Baskaran, Krishnan, Ren, Thyagarajan: Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel-dependent mechanisms. in British journal of pharmacology 2016 (PubMed)

  3. Human Polyclonal PRDM16 Primary Antibody für ELISA, WB - ABIN184809 : Mochizuki, Shimizu, Nagasawa, Tanaka, Taniwaki, Yokota, Morishita: A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells. in Blood 2000 (PubMed)

Weitere Antikörper gegen PRDM16 Interaktionspartner

Zebrafish PR Domain Containing 16 (PRDM16) Interaktionspartner

  1. Prdm3 (zeige MECOM Antikörper) and prdm16 are strongly expressed in the pharyngeal arches during cranioskeletal development, and their knockdown leads to defects in both the viscerocranium and the neurocranium.

Cow (Bovine) PR Domain Containing 16 (PRDM16) Interaktionspartner

  1. Animals with the homozygote PRDM16 genotype had lower body weight and average daily gain than those with the other genotypes.

  2. The genetic variation within PRDM16 gene in 1031 Chinese indigenous bovine, was analyzed.

Human PR Domain Containing 16 (PRDM16) Interaktionspartner

  1. Flow cytometric analysis and western blot analysis of apoptosisassociated proteins indicated that PRDM16 has an antiapoptotic role in prostatic cancer cells. In addition, the spliced form, sPRDM16/MEL1S, was detected to be overexpressed in PCa (zeige FLVCR1 Antikörper) cell lines. In conclusion, the present study indicated an important oncogenic role in prostate cancer.

  2. A single risk variant, rs2651899 in PRDM16, was significantly associated with efficacy of triptans in migraine patients

  3. High PRDM16 expression is associated with astrocytoma.

  4. Our results suggest that K568 SUMOylation of sPRDM16 plays an important role in the progression of acute myeloid leukemia (zeige BCL11A Antikörper).

  5. Results show that PRDM16 overexpression was highly recurrent in de novo paediatric AML (zeige RUNX1 Antikörper) and is associated with adverse outcome

  6. PRDM16 might contribute to maintain adipose tissue "white fat" gene expression profile and systemic metabolic homeostasis.

  7. EVI1 (zeige MECOM Antikörper) and MEL1 are homolog genes whose transcriptional activations by chromosomal translocations have roles in Japanese pediatric acute myeloid leukemia (zeige BCL11A Antikörper)

  8. Three novel loci were identified in East Asians with cardiac arrhythmias: rs2483280 (PRDM16 locus) and rs335206 (PRDM6 (zeige PRDM6 Antikörper) locus) were associated with QRS (zeige QARS Antikörper) duration; and rs17026156 (SLC8A1 (zeige SLC8A1 Antikörper) locus) correlated with PR interval.

  9. Genetic analyses uncovered the importance of the PRDM16 gene in the regulation of lean body mass.

  10. MED1 (zeige MED1 Antikörper) is required for optimal PRDM16-induced Ucp1 (zeige UCP1 Antikörper) expression

Mouse (Murine) PR Domain Containing 16 (PRDM16) Interaktionspartner

  1. Gelidium elegans stimulates the expression of PRDM16 and UCP-1 (zeige UCP1 Antikörper) Protein in brown adipose tissue and suppresses hyperglycemia in high-fat diet mice.

  2. Both gain- and loss-of-function studies showed that an accumulation of the CCAAT/enhancer binding protein-beta (C/EBP-beta (zeige CEBPB Antikörper)) protein, which cooperates with dominant transcriptional co-regulator PR domain containing 16 (PRDM16) to determine brown/beige (zeige LYST Antikörper) adipocyte lineage, is essential for the enhanced adipocyte browning caused by the loss of ZIP13 (zeige SLC39A13 Antikörper)

  3. Prdm16 plays an important role in dynamic cellular redox changes in developing neocortex during neural differentiation.

  4. Together, these data indicate that PRDM16 diminishes responsiveness to type I interferon (zeige IFNA Antikörper) in adipose cells to promote thermogenic and mitochondrial function.

  5. the cellular levels of alpha-ketoglutarate (alphaKG), a key metabolite required for TET-mediated DNA demethylation, were profoundly increased and required for active DNA demethylation of the Prdm16 promoter.

  6. We further show that Cdkn1c (zeige CDKN1C Antikörper) is required for post-transcriptional accumulation of the brown fat determinant PR domain containing 16 (PRDM16) and that CDKN1C (zeige CDKN1C Antikörper) and PRDM16 co-localise to the nucleus of rare label-retaining cell within iBAT (zeige SLC10A2 Antikörper).

  7. PRDM16-induced C2C12 transdifferentiation is associated with alterations in CpG methylation of myogenic factors, and PR domain affects both myogenesis and adipogenesis with modified histone methylation marks on MyoD (zeige MYOD1 Antikörper) and PPARgamma (zeige PPARG Antikörper) promoters

  8. PRDM16 deficiency in BAT (zeige BAAT Antikörper) reduces MED1 (zeige MBD4 Antikörper) binding at PRDM16 target sites and causes a fundamental change in chromatin architecture at key brown fat-selective genes

  9. Prdm16 and Prdm3 (zeige MECOM Antikörper) control postnatal BAT (zeige BAAT Antikörper) identity and function.

  10. Study reveals that Prdm16 expression is regulated through Gcn5 (zeige KAT2A Antikörper)/PCAF (zeige KAT2B Antikörper) during brown adipogenesis.

PRDM16 Antigen-Profil

Beschreibung des Gens

The reciprocal translocation t(1\;3)(p36\;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with PRDM16

  • PR domain containing 16 (PRDM16) Antikörper
  • PR domain containing 16 (prdm16) Antikörper
  • PR domain containing 16 (Prdm16) Antikörper
  • 5730557K01Rik Antikörper
  • C130091E20 Antikörper
  • csp1 Antikörper
  • mel1 Antikörper
  • mKIAA1675 Antikörper
  • PFM13 Antikörper
  • PRDM16 Antikörper
  • wu:fc09g08 Antikörper

Bezeichner auf Proteinebene für PRDM16

PR domain containing 16 , fc09g08 , PR domain zinc finger protein 16-like , MDS1/EVI1-like gene 1 , PR domain zinc finger protein 16 , transcription factor MEL1 , PR domain-containing protein 16 , line 27

GENE ID SPEZIES
419388 Gallus gallus
457227 Pan troglodytes
559174 Danio rerio
100060844 Equus caballus
100137803 Bos taurus
100481590 Ailuropoda melanoleuca
100592850 Nomascus leucogenys
63976 Homo sapiens
70673 Mus musculus
100366024 Rattus norvegicus
479582 Canis lupus familiaris
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