E-cadherin Proteine (CDH1)

Bezeichnung:
Cadherin 1, Type 1, E-Cadherin (Epithelial) Proteine (CDH1)
Auf www.antikoerper-online.de finden Sie aktuell 37 Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Proteine von 13 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen E-cadherin Antikörper (860) und E-cadherin Kits (83) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1007 E-cadherin Produkte verfügbar.
Synonyme:
AA960649, arc-1, Arc1, b-cadherin, c-cadherin, cad17, cadherin-1, cadherin-17, cd324, CDH1, cdh1-a, cdh16, cdhc-A, cdhe, cdhp, dZ71B9.1, E-cad, E-cadherin, Ecad, hjmd, hpt-1, hpt1, L-CAM, lcam, LI-cadherin, pcad, si:dz180o5.1, si:dz180o5.2, Um, uvo, uvomorulin, xb-cad, XB-cadherin, XBcad, xcdh1, XTCAD-1
alle Proteine anzeigen Gen GeneID UniProt
CDH1 999 P12830
CDH1 83502 Q9R0T4
CDH1 12550 P09803

Weitere Synonyme anzeigen

E-cadherin Proteine (CDH1) nach Spezies

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Am meisten referenzierte E-cadherin Proteine

  1. Rat (Rattus) E-cadherin Protein expressed in Human Cells - ABIN2009409 : Berx, Staes, van Hengel, Molemans, Bussemakers, van Bokhoven, van Roy: Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). in Genomics 1995 (PubMed)
    Zeige alle 5 Referenzen für 2009409

  2. Mouse (Murine) E-cadherin Protein expressed in Human Cells - ABIN2008138 : Yoshiura, Kanai, Ochiai, Shimoyama, Sugimura, Hirohashi: Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. in Proceedings of the National Academy of Sciences of the United States of America 1995 (PubMed)
    Zeige alle 5 Referenzen für 2008138

  3. Human E-cadherin Protein expressed in Human Cells - ABIN2002344 : Becker, Atkinson, Reich, Becker, Nekarda, Siewert, Höfler: E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. in Cancer research 1994 (PubMed)
    Zeige alle 5 Referenzen für 2002344

  4. Human E-cadherin Protein expressed in HEK-293 Cells - ABIN2180987 : Agiostratidou, Muros, Shioi, Marambaud, Robakis: The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of A beta precursors. in Journal of neurochemistry 2006 (PubMed)
    Zeige alle 4 Referenzen für 2180987

  5. Human E-cadherin Protein expressed in Wheat germ - ABIN3013372 : Tsunematsu, Takihara, Ishimaru, Pagano, Takata, Kudo: Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis. in Nature communications 2013 (PubMed)

Weitere Proteine zu E-cadherin Interaktionspartnern

Xenopus laevis Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Interaktionspartner

  1. E-cadherin has a role in cranial neural crest migration in Xenopus laevis

  2. the switch from E- to N-cadherin (zeige CDH2 Proteine) during epithelial-mesenchymal transition is essential for acquisition of Contact inhibition of locomotion behavior.

  3. Moderate attenuation of C-cadherin function affects cell adhesion but not gastrulation.

  4. Because paraxial protocadherin and C-cadherin do not directly interact nor form a joint complex with Fz7, Wnt-11 triggers formation of two distinct complexes that act in parallel to reduce cell adhesion by hampering clustering of C-cadherin.

  5. The functional and physical relationships between PAPC, FLRT3, and C-cadherin, was investigated.

  6. PAPC mediates these functions by down-regulating the adhesion activity of C-cadherin.

  7. Results suggest that the basis for cell segregation during morphogenesis does not map exclusively to protein-level differences in E-, N-, or C-cadherin adhesion.

  8. G-protein-coupled receptors control cortical actin assembly by controlling the amount of cadherin expressed on the cell surface.

  9. Two stage cadherin kinetics require multiple extracellular domains but not the cytoplasmic region

  10. Data show that the intracellular domain of PAPC (Protocadherin) interacts with Sprouty (Spry), and upon binding to PAPC, Spry function is inhibited and PCP signaling is enhanced.

Mouse (Murine) Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Interaktionspartner

  1. JNK (zeige MAPK8 Proteine) signaling, which is inversely correlated with WNT4 (zeige WNT4 Proteine), plays an important role in perinatal germline cyst breakdown and primordial follicle formation by regulating E-cadherin junctions between oocytes in mouse ovaries.

  2. The expression level of E-cadherin protein was significantly decreased in fibrotic livers.

  3. We conclude that p120ctn (zeige CTNND1 Proteine) is not only an adaptor and regulator of E-cadherin, but is also indispensable for proper lineage commitment.

  4. The reduction in tumor growth in fat1 mice compared with wildtype controls may have been associated, in part, to the: i) Increased expression of Ecadherin and the reduced expression of its transcriptional repressors.

  5. These observations suggest that the overexpression of CatE (zeige CTSE Proteine) interferes with neuronal differentiation of P19 (zeige CDKN2D Proteine) cells through an impairment of cell aggregate formation, possibly through proteolytic degradation of N-cadherin (zeige CDH2 Proteine).

  6. E-cadherin-mediated cell-cell contacts can modulate osteoclast-specific gene expression and prompt differentiating osteoclast precursors toward migratory and fusion activities.

  7. These results provide a new mechanism by which LXA4 inhibits LPS (zeige TLR4 Proteine)-induced ALI through Nrf2 (zeige NFE2L2 Proteine)-mediated E-cadherin expression

  8. Demonstrate that HBx-HCCR-E-cadherin regulation pathway might play an important role in HBV-induced hepatocarcinogenesis.

  9. E-cadherin expression regulates inflammatory mediators in macrophages.

  10. Increased expression of E-cadherin binds to and sequesters beta-catenin (zeige CTNNB1 Proteine) away from downstream Wnt (zeige WNT2 Proteine) signaling proteins.

Human Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Interaktionspartner

  1. Study demonstrate that CdGAP acts as a novel co-transcriptional repressor with Zeb2 to suppress E-cadherin expression in breast cancer cells.

  2. The transforming growth factor beta (TGF-beta) pathway is required for E-cadherin loss to induce inhibition of Nucleotide Excision Repair.

  3. Results indicate that HCV core induced epithelial-mesenchymal transition (EMT (zeige ITK Proteine)) by interacting with the transcriptional repressor complex Snail (zeige SNAI1 Proteine)/HDAC1 (zeige HDAC1 Proteine)/2 at the E-cadherin promoter, which led to E-cadherin repression and increased invasiveness of hepatoma cells.

  4. House dust mite exposure on human bronchial epithelial cells (16HBE) increased the expression of TSLP (zeige TSLP Proteine) and E-cadherin dysfunction by PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) signaling pathway. Exposure of 16HBE to TSLP (zeige TSLP Proteine) and HDM (zeige HDAC3 Proteine) resulted in aberrant cleavage and redistribution of E-cadherin.

  5. Application of force to E-cadherin stimulates liver kinase B1 (zeige STK11 Proteine) to activate AMP-activated protein kinase (zeige PRKAA2 Proteine), a master regulator of energy homeostasis. LKB1 (zeige STK11 Proteine) recruits AMPK (zeige PRKAA1 Proteine) to the E-cadherin mechanotransduction complex, thereby stimulating actomyosin contractility, glucose uptake and ATP production.

  6. Expression of CDH1 and CD24 (zeige CD24 Proteine) was transcriptionally upregulated by direct binding of HOXA5 (zeige HOXA5 Proteine) to their promoter sequences as demonstrated by luciferase and ChIP analyses

  7. the loss of MUC16 (zeige MUC16 Proteine) and E-cadherin expression resulted in the formation of more compact spheroids. In addition, our data describe an unusual link between E-cadherin expression and less compact spheroids. Our data also emphasize the role of MUC16 (zeige MUC16 Proteine) and b1 integrin in Epithelial ovarian cancer (EOC) spheroid formation.

  8. CDH1 expression in high grade papillary urothelial carcinomas predicted disease-free survival and overall survival.

  9. Higher proportions of early-onset Diffuse Gastric Cancers (DGCs) contained somatic mutations in CDH1 or TGFBR1 (zeige TGFBR1 Proteine) compared with late-onset DGCs. A smaller proportion of early-onset DGCs contained somatic mutations in RHOA (zeige RHOA Proteine). CDH1 alterations, but not RHOA (zeige RHOA Proteine) mutations, were associated with shorter survival times. Female predominance in early-onset DGC (zeige GGCX Proteine) may be related to relatively high rates of somatic CDH1 and TGFBR1 (zeige TGFBR1 Proteine) mutations.

  10. Studies indicate that Grainyhead-like transcription factor 2 (zeige HNF1B Proteine) (GRHL2 (zeige GRHL2 Proteine)) controls the expression of E-cadherin (CDH1) required for adherens junctions and possibly regulates the expression of claudin-4 (CLDN4 (zeige CLDN4 Proteine)) in tight junctions.

Pig (Porcine) Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Interaktionspartner

  1. E-cadherin mRNA/protein were up-regulated in all flutamide-treated corpus luteum of mid- and late pregnancy.

  2. In pig kidney, strong E-cadherin expression was observed in the basolateral plasma membrane of the tubular epithelial cells. E-cadherin immunolabeling was not detected in glomeruli or blood vessels of pig kidney.

  3. Localisation of NANOG (zeige NANOG Proteine), OCT4 (zeige POU5F1 Proteine), and E-CADHERIN in porcine pre- and peri (zeige PLIN1 Proteine)-implantation embryos.

  4. The epiblast expressed epithelial markers, MUC1 (zeige MUC1 Proteine) and E-CADHERIN, and the pluripotency markers, DNMT3B (zeige DNMT3B Proteine) and CRIPTO (zeige TDGF1 Proteine).

Cow (Bovine) Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Interaktionspartner

  1. Transfection of zygotes with 100 and 200 nM E-cadherin siRNA led to a 72 and 38% reduction, respectively, in E-cadherin mRNA relative abundance in Day 7 blastocysts compared with controls.

  2. E-cadherin and beta-catenin (zeige CTNNB1 Proteine) were distributed not only at the cell to cell boundary but throughout the cytoplasm in binucleate trophoblast cells

  3. Results describe the effect of suppression of connexin 43 (zeige GJA1 Proteine) and E-cadherin on the development, mRNA and protein expression of bovine blastocysts cultured in vitro or in vivo.

Zebrafish Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Interaktionspartner

  1. E-cadherin mRNA coinjection demonstrated the specificity of cdh1 morpholino oligonucleotides-induced defects

  2. Results suggest that Wnt11 (zeige WNT11 Proteine) controls tissue morphogenesis by modulating E-cadherin-mediated cell cohesion through Rab5c (zeige Rab5c Proteine), a novel mechanism of Wnt (zeige WNT2 Proteine) signaling in gastrulation.

E-cadherin (CDH1) Protein Überblick

Protein Überblick

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Alternative names and synonyms associated with E-cadherin (CDH1)

  • cadherin 1, type 1, E-cadherin (epithelial) (CDH1)
  • si:busm1-180o5.2 (si:busm1-180o5.2)
  • cadherin 1, epithelial (cdh1)
  • cadherin 1 (Cdh1)
  • si:busm1-180o5.1 (si:busm1-180o5.1)
  • cadherin 1, type 1, E-cadherin (epithelial) (cdh1)
  • cadherin 17, LI cadherin (liver-intestine) (CDH17)
  • Cadherin-17 (cad17)
  • cadherin 17, LI cadherin (liver-intestine) (cdh17)
  • cadherin 3, type 1, P-cadherin (placental) (cdh3-a)
  • E-cadherin-like (LOC100356548)
  • Aerobic running capacity QTL 1 (Arunc1)
  • cadherin 1, type 1, E-cadherin (epithelial) (Cdh1)
  • AA960649 Protein
  • arc-1 Protein
  • Arc1 Protein
  • b-cadherin Protein
  • c-cadherin Protein
  • cad17 Protein
  • cadherin-1 Protein
  • cadherin-17 Protein
  • cd324 Protein
  • CDH1 Protein
  • cdh1-a Protein
  • cdh16 Protein
  • cdhc-A Protein
  • cdhe Protein
  • cdhp Protein
  • dZ71B9.1 Protein
  • E-cad Protein
  • E-cadherin Protein
  • Ecad Protein
  • hjmd Protein
  • hpt-1 Protein
  • hpt1 Protein
  • L-CAM Protein
  • lcam Protein
  • LI-cadherin Protein
  • pcad Protein
  • si:dz180o5.1 Protein
  • si:dz180o5.2 Protein
  • Um Protein
  • uvo Protein
  • uvomorulin Protein
  • xb-cad Protein
  • XB-cadherin Protein
  • XBcad Protein
  • xcdh1 Protein
  • XTCAD-1 Protein

Bezeichner auf Proteinebene für CDH1

CAM 120/80 , E-Cadherin , cadherin 1, E-cadherin (epithelial) , cadherin-1 , calcium-dependent adhesion protein, epithelial , cell-CAM 120/80 , epithelial cadherin , uvomorulin , hypothetical protein LOC368517 , cadherin 1, epithelial , hab , half baked , E-cadherin , hypothetical protein LOC368516 , cadherin 1, type 1, E-cadherin (epithelial) , HPT-1 cadherin , LI cadherin , LI-cadherin , cadherin-16 , cadherin-17 , human intestinal peptide-associated transporter HPT-1 , human peptide transporter 1 , intestinal peptide-associated transporter HPT-1 , liver-intestine cadherin , xTCAD-1 , Cadherin-17 , cadherin 17, LI cadherin (liver-intestine) , Li cadherin , C-cadherin (EP-cadherin) , EP-cadherin , ARC-1 , L-CAM , liver cell adhesion molecule , liver cell adhesion protein , Epithelial cadherin

GENE ID SPEZIES
999 Homo sapiens
368517 Danio rerio
114424 Danio rerio
83502 Rattus norvegicus
368516 Danio rerio
100048953 Sus scrofa
442858 Canis lupus familiaris
779546 Xenopus (Silurana) tropicalis
100294601 Ovis aries
1015 Homo sapiens
100337618 Xenopus laevis
100195084 Salmo salar
100216129 Xenopus (Silurana) tropicalis
394290 Xenopus laevis
12550 Mus musculus
282637 Bos taurus
415860 Gallus gallus
100356548 Oryctolagus cuniculus
100174439 Pongo abelii
444901 Rattus norvegicus
101095391 Felis catus
101119747 Ovis aries
100726210 Cavia porcellus
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