anti-DDR1 (DDR1) Antikörper

Bezeichnung:
anti-Discoidin Domain Receptor tyrosine Kinase 1 Antikörper (DDR1)
Auf www.antikoerper-online.de finden Sie aktuell 169 Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DDR1 Proteine (22) und DDR1 Kits (17) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 223 DDR1 Produkte verfügbar.
Synonyme:
6030432F18, AI323681, CAK, CD167, CD167a, CG9488, CG9490, CG11573, CG13984, CG13985, CG33531, CT33540, DDR, Dmel\\CG33531, Dmel_CG13984, Drd1, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, PTK3D, RTK6, TRKE
Alle Antikörper anzeigen Gen GeneID UniProt
DDR1 12305 Q03146
DDR1 780 Q08345
DDR1 25678  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-DDR1 (DDR1) Antikörper

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anti-Mouse (Murine) DDR1 Antikörper:

anti-Human DDR1 Antikörper:

anti-Rat (Rattus) DDR1 Antikörper:

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Am meisten referenzierte anti-DDR1 Antikörper

  1. Human Polyclonal DDR1 Primary Antibody für FACS, IHC (p) - ABIN392014 : Vogel, Gish, Alves, Pawson: The discoidin domain receptor tyrosine kinases are activated by collagen. in Molecular cell 1998 (PubMed)
    Zeige alle 3 Referenzen für 392014

  2. Human Polyclonal DDR1 Primary Antibody für IHC (p), WB - ABIN392016 : Valent, Meddeb, Danglot, Duverger, Nguyen, Bernheim: Assignment of the NTRK4 (trkE) gene to chromosome 6p21. in Human genetics 1996 (PubMed)
    Zeige alle 3 Referenzen für 392016

  3. Human Monoclonal DDR1 Primary Antibody für ELISA, WB - ABIN969082 : Foehr, Tatavos, Tanabe, Raffioni, Goetz, Dimarco, De Luca, Bradshaw: Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000 (PubMed)
    Zeige alle 3 Referenzen für 969082

  4. Human Polyclonal DDR1 Primary Antibody für IHC (p) - ABIN2478753 : Coakley, Hawkins, Crinis, McManus, Blake, Nordmann, Sloan, Connelly: An unusual case of variegate porphyria with possible homozygous inheritance. in Australian and New Zealand journal of medicine 1990 (PubMed)
    Zeige alle 2 Referenzen für 2478753

  5. Human Polyclonal DDR1 Primary Antibody für FACS, IF - ABIN391458 : Johnson, Edman, Rutter: A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Zeige alle 2 Referenzen für 391458

Weitere Antikörper gegen DDR1 Interaktionspartner

Mouse (Murine) Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Interaktionspartner

  1. DDR-1 interacts with the TGF-beta (zeige TGFB1 Antikörper) pathway to restrict calcifying extracellular vesicle-mediated mineralization and fibrosis by smooth muscle cells.

  2. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (zeige ITGA2 Antikörper) DDR1-mediated ERK (zeige EPHB2 Antikörper) activation.

  3. DDR1 malfunction causes outer hair cells deformation and the separation of the lateral wall, the location of the cellular motor responsible for the electromotile property, explicitly in those regions showing DDR1 and NM-IIA co-localization.

  4. the collagen receptors DDR1 and integrin a2b1 contribute to regulate GBM-maturation and to control matrix accumulation.

  5. Extensive co-localization and relationship of Jag1 (zeige JAG1 Antikörper) and Ddr1 in bile ducts and blood vessels in postnatal liver.

  6. Genetic inhibition of discoidin domain receptor 1 protects mice against crescentic glomerulonephritis.

  7. Data identifyies Syk (zeige SYK Antikörper) as a potent inhibitor of epithelial migration and describes a first functional consequence of the interaction with the collagen receptor (zeige ITGA2 Antikörper) DDR1.

  8. Results show that DDR1 promotes cell-cell adhesion and differentiation through stabilization of E-cadherin (zeige CDH1 Antikörper), which is mediated by Cdc42 (zeige CDC42 Antikörper) inactivation.

  9. Collagen I stimulates the self-renewal of embryonic stem cells mediated by Bmi-1 (zeige BMI1 Antikörper) through alpha2beta1 integrin-dependent ILK (zeige ILK Antikörper), Notch (zeige NOTCH1 Antikörper), Gli-1 (zeige GLI1 Antikörper), and DDR1-dependent Ras, PI3K/Akt (zeige AKT1 Antikörper), and ERK (zeige EPHB2 Antikörper).

  10. Loss of Discoidin domain receptor 1 is associated with inflammation and fibrosis in obstructive nephropathy

Human Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Interaktionspartner

  1. Reduced DDR1 expression may be implicated in impaired melanocyte adhesion process involved in vitiligo (zeige MITF Antikörper) pathogenesis

  2. data demonstrate that TGF-beta1 (zeige TGFB1 Antikörper) favors linear invadosome formation through the expressions of both the inducers, such as collagen and LOXL2 (zeige LOXL2 Antikörper), and the components such as DDR1 and MT1-MMP (zeige MMP14 Antikörper) of linear invadosomes in cancer cells. Meanwhile, our data uncover a new TGF-beta1 (zeige TGFB1 Antikörper)-dependent regulation of DDR1 expression.

  3. DDR1 overexpression promoted GC cell proliferation (p < 0.05), migration (p < 0.01), and invasion (p < 0.01), and accelerated the growth (p < 0.05) as well as the microvessel formation (p < 0.01) of transplantation tumor in nude mice.

  4. Our results suggest that DDR1 is both a prognostic marker for renal clear cell carcinoma and a potential functional target for therapy

  5. Study concludes that non-canonical DDR1 signaling enables breast cancer cells to exploit the ubiquitous interstitial matrix component collagen I to undergo metastatic reactivation in multiple target organs.

  6. Upregulation of DDR1 collagen receptor (zeige ITGA2 Antikörper) is associated with breast cancer.

  7. Knockdown DDR1 reversed the effects of Galpha13 (zeige GNA13 Antikörper) knockdown on cell-cell adhesion and proteolytic invasion in three-dimensional collagen.

  8. Data suggest SCl2 (Streptococcus pyogenes) binds to DDR (DDR1, DDR2 (zeige DDR2 Antikörper)) ectodomain w/o stimulating receptor signaling; here, protein engineering was used to construct SCl (zeige KRT7 Antikörper)-like proteins that inhibit collagen-DDR interactions and macrophage migration.

  9. DDR1 is a key modulator of RIT (zeige RIT1 Antikörper) activity.

  10. DDR1 expression is a prognostic indicator in pancreatic ductal carcinoma.

DDR1 Antigen-Profil

Beschreibung des Gens

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with DDR1

  • Discoidin domain receptor (Ddr) Antikörper
  • discoidin domain receptor family, member 1 (Ddr1) Antikörper
  • discoidin domain receptor tyrosine kinase 1 (DDR1) Antikörper
  • discoidin domain receptor tyrosine kinase 1 (Ddr1) Antikörper
  • 6030432F18 Antikörper
  • AI323681 Antikörper
  • CAK Antikörper
  • CD167 Antikörper
  • CD167a Antikörper
  • CG9488 Antikörper
  • CG9490 Antikörper
  • CG11573 Antikörper
  • CG13984 Antikörper
  • CG13985 Antikörper
  • CG33531 Antikörper
  • CT33540 Antikörper
  • DDR Antikörper
  • Dmel\\CG33531 Antikörper
  • Dmel_CG13984 Antikörper
  • Drd1 Antikörper
  • EDDR1 Antikörper
  • HGK2 Antikörper
  • MCK10 Antikörper
  • NEP Antikörper
  • NTRK4 Antikörper
  • PTK3 Antikörper
  • PTK3A Antikörper
  • PTK3D Antikörper
  • RTK6 Antikörper
  • TRKE Antikörper

Bezeichner auf Proteinebene für DDR1

CG33531-PA , CG33531-PB , Ddr-PA , Ddr-PB , discoidin domain receptor , CD167 antigen-like family member A , cell adhesion kinase , discoidin receptor tyrosine kinase , epithelial discoidin domain receptor 1 , epithelial discoidin domain-containing receptor 1 , protein-tyrosine kinase MPK-6 , tyrosine kinase DDR , tyrosine-protein kinase CAK , PTK3A protein tyrosine kinase 3A , mammary carcinoma kinase 10 , neuroepithelial tyrosine kinase , neurotrophic tyrosine kinase, receptor, type 4 , protein-tyrosine kinase RTK-6 , discoidin domain receptor family, member 1 , neurotrophic tyrosine kinase receptor type 4 , protein-tyrosine kinase 3 , protein-tyrosine kinase PTK-3

GENE ID SPEZIES
3346209 Drosophila melanogaster
12305 Mus musculus
780 Homo sapiens
25678 Rattus norvegicus
100144462 Sus scrofa
462548 Pan troglodytes
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