anti-P2RX7 (P2RX7) Antikörper

anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 Antikörper (P2RX7)
Auf finden Sie aktuell 120 Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen P2RX7 Kits (16) und P2RX7 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 153 P2RX7 Produkte verfügbar.
AI467586, P2RX7, P2X(7), p2x7, P2X7R, p2xr7

Meistgesuchte Reaktivitäten zu anti-P2RX7 (P2RX7) Antikörper

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anti-Human P2RX7 Antikörper:

anti-Mouse (Murine) P2RX7 Antikörper:

anti-Rat (Rattus) P2RX7 Antikörper:

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Am meisten referenzierte anti-P2RX7 Antikörper

  1. Rat (Rattus) Polyclonal P2RX7 Primary Antibody für WB - ABIN1742370 : Young, Brutkowski, Lien, Arkle, Lochmüller, Zabłocki, Górecki: P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment. in Journal of cellular and molecular medicine 2012 (PubMed)
    Zeige alle 3 Referenzen für 1742370

  2. Human Polyclonal P2RX7 Primary Antibody für IHC (p), WB - ABIN651861 : Kim, Jiang, Wilson, North, Surprenant: Proteomic and functional evidence for a P2X7 receptor signalling complex. in The EMBO journal 2001 (PubMed)
    Zeige alle 2 Referenzen für 651861

  3. Cow (Bovine) Polyclonal P2RX7 Primary Antibody für IHC, WB - ABIN2776335 : Buell, Talabot, Gos, Lorenz, Lai, Morris, Antonarakis: Gene structure and chromosomal localization of the human P2X7 receptor. in Receptors & channels 1999 (PubMed)
    Zeige alle 2 Referenzen für 2776335

  4. Human Polyclonal P2RX7 Primary Antibody für IHC (p), IHC - ABIN451826 : Tomasinsig, Pizzirani, Skerlavaj, Pellegatti, Gulinelli, Tossi, Di Virgilio, Zanetti: The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. in The Journal of biological chemistry 2008 (PubMed)

  5. Human Polyclonal P2RX7 Primary Antibody für IF (p), IHC (p) - ABIN1386314 : Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation. in International journal of molecular medicine 2015 (PubMed)

  6. Cow (Bovine) Polyclonal P2RX7 Primary Antibody für WB - ABIN2776151 : Al-Shukaili, Al-Kaabi, Hassan: A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. in Inflammation 2008 (PubMed)

Weitere Antikörper gegen P2RX7 Interaktionspartner

Zebrafish Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Interaktionspartner

  1. Blockade of the P2X7 receptor reduces cyst formation via ERK (zeige MAPK1 Antikörper)-dependent pathways in a zebrafish model of polycystic kidney disease.

Human Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Interaktionspartner

  1. P2X7R expression was correlated with enhanced tumor grade and metastasis in colorectal carcinoma patients.

  2. Our present study shows that loss of function of the P2X7 receptor in mice induces retinal changes representing characteristics of early age-related macular degeneration.

  3. Single nucleotide polymorphism in P2X7R gene is associated with pulmonary non-tuberculous mycobacterial disease.

  4. Our results reveal that P2RX7 rs2230911 may be associated with primary gout risk in a Chinese Han male population and allele G may be a susceptibility factor for primary gout.

  5. Together, this body of research suggests that P2X7R may constitute an important therapeutic target for a variety of neurological disorders.

  6. In addition, purinergic receptor P2X, ligand-gated ion channel (zeige GLRa3 Antikörper) 7 (P2X7) was downregulated in CD36 (zeige CD36 Antikörper)-knockdown 3T3-L1 cells, suggesting that the suppression of CD36 (zeige CD36 Antikörper) attenuates adipogenesis via the P2X7 pathway in 3T3-L1 cells.

  7. analysis of the M1/M2 functional imprinting of primary microglia and the role played by P2X7 and miR (zeige MLXIP Antikörper)-125b in amyotrophic lateral sclerosis microglia activation [review]

  8. Study observed a downregulation of purinergic P2X7 receptors in peripheral blood mononuclear cells of amyotrophic lateral sclerosis (ALS) patients compared to controls.

  9. Data suggest that specific serine residues in purinergic receptors play key roles in both agonist binding and receptor sensitization/desensitization: in rat P2rx7, point mutation F288S (phenylalanine 288 > serine) results in a slower rate of ATP binding/unbinding and stabilization of non-sensitized receptor states; in human P2RX7, Y288F (but not Y288S) results in a "rat-like" receptor with a fast deactivation rate.

  10. This study showed that the ATP-gated P2X7 receptor is upregulated in experimental epilepsy and resected hippocampus from epilepsy patients.

Cow (Bovine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Interaktionspartner

  1. For the inflammasome-dependent IL-1beta (zeige IL1B Antikörper) release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta (zeige IL1B Antikörper) release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.

Mouse (Murine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Interaktionspartner

  1. P2X7 deficiency resolved atherosclerotic plaque inflammation by inhibition of inflammasome activation.

  2. P2RX7 purinoceptor gene knockout alters some of the morphological and mechanical properties of dystrophic bones in a mouse model.

  3. restoration of cholesterol concentrations in cells lacking lipin-2 (zeige LPIN2 Antikörper) decreases ion currents through the P2X7 receptor, and downstream events that drive IL-1beta (zeige IL1B Antikörper) production.

  4. Western blotting indicated altered P2X7R, P2Y2R (zeige P2RY2 Antikörper) and P2Y4R (zeige P2RY4 Antikörper) expression in high glucose exposed bone cells, and in diabetic bone tissue. Moreover, high glucose blunted normal P2R- and flow-induced Ca2 (zeige CA2 Antikörper)+ signaling and ATP release from osteocytes

  5. Together, these results demonstrate that activation of the P2X7 receptor is involved in the exacerbated immune response observed during influenza virus infection.

  6. this study shows that blockage of P2X7R by brilliant blue G exerts a protective effect on graft versus host reaction post hematopoietic stem cell transplantation and improves liver function suggesting that this receptor could be considered as an attractive target for treatment of GVHD

  7. In response to SD, the KO mice failed to increase hypothalamic adenosine deaminase (zeige ADA Antikörper) and P2X4R (zeige P2RX4 Antikörper) mRNAs. Further, hypothalamic lncRNA expressions varied by strain, and with SD. Current data are consistent with a role for the P2X7R in thermoregulation and lncRNA involvement in purinergic signaling.

  8. In the brain samples, expressions of P2Y4 (zeige P2RY4 Antikörper) and P2X7 were significantly reduced, whereas that of P2Y1 (zeige P2RY1 Antikörper) was significantly elevated in an age-dependent manner.

  9. results suggest a neuronal activity-dependent P2X7R expression which is induced by the transcription factor Sp1 (zeige SP1 Antikörper) and repressed in a calcium-dependent manner by microRNA-22

  10. The data are consistent with the hypothesis that P2X7R contributes to alveolar epithelial barrier function through effects on GSK-3beta (zeige GSK3b Antikörper).

P2RX7 Antigen-Profil

Beschreibung des Gens

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Alternative names and synonyms associated with P2RX7

  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7) Antikörper
  • purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7) Antikörper
  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7) Antikörper
  • AI467586 Antikörper
  • P2RX7 Antikörper
  • P2X(7) Antikörper
  • p2x7 Antikörper
  • P2X7R Antikörper
  • p2xr7 Antikörper

Bezeichner auf Proteinebene für P2RX7

P2X purinoceptor 7 , purinergic receptor P2X, ligand-gated ion channel, 7 , p2X purinoceptor 7-like , ATP receptor , P2X7 receptor , P2Z receptor , purinergic receptor P2X7 variant A , P2X7 purinoceptor , purinergic receptor P2X7

100058464 Equus caballus
387298 Danio rerio
452318 Pan troglodytes
699455 Macaca mulatta
771952 Gallus gallus
100458463 Pongo abelii
100588362 Nomascus leucogenys
5027 Homo sapiens
448778 Canis lupus familiaris
286814 Bos taurus
18439 Mus musculus
29665 Rattus norvegicus
497623 Sus scrofa
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