anti-Spectrin alpha 1, Erythrocytic (SPTA1) Antikörper

Auf finden Sie aktuell 11 Spectrin alpha 1, Erythrocytic (SPTA1) Antikörper von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Spectrin alpha 1, Erythrocytic Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 15 Spectrin alpha 1, Erythrocytic Produkte verfügbar.
AF093576, AI451697, EL2, ha, HPP, HS3, ihj, nmf4, sph, SPH3, Spna-1, Spna1, SPTA
Alle Antikörper anzeigen Gen GeneID UniProt
SPTA1 289257  
SPTA1 20739 P08032
SPTA1 6708 P02549

Meistgesuchte Reaktivitäten zu anti-Spectrin alpha 1, Erythrocytic (SPTA1) Antikörper

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Weitere Antikörper gegen Spectrin alpha 1, Erythrocytic Interaktionspartner

Mouse (Murine) Spectrin alpha 1, Erythrocytic (SPTA1) Interaktionspartner

  1. This study demonstrates that the FGF19 (zeige FGF19 Antikörper)-SHP (zeige LAMC1 Antikörper)-LSD1 (zeige KDM1A Antikörper) axis maintains homeostasis by suppressing unnecessary autophagic breakdown of cellular components, including lipids, under nutrient-rich postprandial conditions.

  2. a new function for spectrins in the stability of invadosomes and the coupling between actin regulation and ECM (zeige MMRN1 Antikörper) degradation

  3. Calcium plays a role in regulating the expression and function of beta-adducin to sustain normal organization of the spectrin-based cytoskeleton and the differentiation properties in keratinocytes through the calmodulin/EGFR/cadherin signaling pathway.

  4. organization of a spectrin-like cytoskeleton is associated with keratinocyte differentiation, and cytoskeleton disruption is mediated by either PKCdelta (zeige PKCd Antikörper)(Thr505) phosphorylation associated with phosphorylated adducin or due to reduction of endogenous adducin

  5. Results of this study provide evidence for a role for spectrin in different steps of megakaryocyte development through its participation in the formation of invaginated membranes and in the maintenance of proplatelet structure.

  6. Analysis of 3 new alleles reveals previously unknown consequences of red blood cell (RBC (zeige CACNA1C Antikörper)) spectrin deficiency, resulting in markedly reduced RBC (zeige CACNA1C Antikörper) membrane spectrin content, decreased band 3 (zeige SLC4A1 Antikörper), and absent beta-adducin (zeige ADD2 Antikörper).

  7. Murine recessive hereditary spherocytosis, sph/sph (zeige NUMA1 Antikörper), is caused by a mutation in the erythroid alpha-spectrin gene.

Human Spectrin alpha 1, Erythrocytic (SPTA1) Interaktionspartner

  1. A novel SPTA1 mutation (H54P) was identified in a case of hereditary elliptocytosis.

  2. The authors show that SUB1-mediated processing of MSP1 is important for parasite viability, the processing modifies the secondary structure of MSP1 and activates its capacity to bind spectrin.

  3. The authors demonstrate that the initial vacuolar membrane around internalized Babesia divergens is formed from protein and lipid components of the red blood cells plasma membrane, including band 3, glycophorin A and spectrin.

  4. a new function for spectrins in the stability of invadosomes and the coupling between actin regulation and ECM (zeige MMRN1 Antikörper) degradation

  5. Case Report: severe hemolytic jaundice and a phenotype of hereditary spherocytosis due alpha-spectrin (zeige SPTAN1 Antikörper) mutations.

  6. In this review, we summarize the state of knowledge about interactions between spectrin and membrane lipids

  7. A novel exon 2 alpha spectrin (zeige SPTAN1 Antikörper) mutation is identified in two families of European ancestry with hereditary pyropoikilocytosis.

  8. The heterozygous c.121C>T mutation of SPTA1 gene induces an amino acid change p.Arg41Trp in the alpha1 domain of the alpha-spectrin (zeige SPTAN1 Antikörper) protein.

  9. Data show that transcription cofactor TAF3 (zeige TAF3 Antikörper) is required for transcription of the alpha spectrin (zeige SPTAN1 Antikörper) SPTA1 gene.

  10. The common hereditary elliptocytosis-associated alpha-spectrin leucine260proline mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation.

Spectrin alpha 1, Erythrocytic (SPTA1) Antigen-Profil

Beschreibung des Gens

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

Alternative names and synonyms associated with Spectrin alpha 1, Erythrocytic (SPTA1)

  • spectrin, alpha, erythrocytic 1 (elliptocytosis 2) (Spta1) Antikörper
  • spectrin alpha, erythrocytic 1 (Spta1) Antikörper
  • spectrin, alpha, erythrocytic 1 (elliptocytosis 2) (SPTA1) Antikörper
  • AF093576 Antikörper
  • AI451697 Antikörper
  • EL2 Antikörper
  • ha Antikörper
  • HPP Antikörper
  • HS3 Antikörper
  • ihj Antikörper
  • nmf4 Antikörper
  • sph Antikörper
  • SPH3 Antikörper
  • Spna-1 Antikörper
  • Spna1 Antikörper
  • SPTA Antikörper

Bezeichner auf Proteinebene für SPTA1

erythroid spectrin alpha , spectrin alpha chain, erythrocyte , alpha-spectrin 1, erythroid , erythroid alpha-spectrin , hemolytic anemia , neuroscience mutagenesis facility, 4 , spectrin alpha 1 , spectrin alpha chain, erythrocytic 1 , spherocytosis , alpha-I spectrin

289257 Rattus norvegicus
20739 Mus musculus
6708 Homo sapiens
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