anti-RASA1 (RASA1) Antikörper

Bezeichnung:
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 Antikörper (RASA1)
Auf www.antikoerper-online.de finden Sie aktuell 107 RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RASA1 Kits (5) und RASA1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 123 RASA1 Produkte verfügbar.
Synonyme:
CG9209, CM-AVM, CMAVM, D-RasGAP, Dmel\\CG9209, Gap, GAPX, p120GAP, p120RASGAP, PKWS, RAS-GAP, Rasa, RASGAP
Alle Antikörper anzeigen Gen GeneID UniProt
RASA1 5921 P20936
RASA1 25676 P50904
RASA1 218397  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-RASA1 (RASA1) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human RASA1 Antikörper:

anti-Rat (Rattus) RASA1 Antikörper:

anti-Mouse (Murine) RASA1 Antikörper:

Alle verfügbaren anti-RASA1 Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-RASA1 Antikörper

  1. Chicken Monoclonal RASA1 Primary Antibody für IF, IP - ABIN967706 : Cichowski, Santiago, Jardim, Johnson, Jacks: Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor. in Genes & development 2003 (PubMed)
    Zeige alle 5 Referenzen für 967706

  2. Human Monoclonal RASA1 Primary Antibody für WB - ABIN395417 : Hemerly, Bastos, Cerutti: Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas. in European journal of endocrinology / European Federation of Endocrine Societies 2010 (PubMed)
    Zeige alle 5 Referenzen für 395417

  3. Human Polyclonal RASA1 Primary Antibody für EIA, WB - ABIN954457 : Wiemels, Kang, Chang, Zheng, Kouyoumji, Zhang, Smith, Scelo, Metayer, Buffler, Wiencke: Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia. in Blood cells, molecules & diseases 2010 (PubMed)
    Zeige alle 5 Referenzen für 954457

  4. Human Polyclonal RASA1 Primary Antibody für WB - ABIN656874 : Oinuma, Ito, Katoh, Negishi: Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons. in The Journal of biological chemistry 2010 (PubMed)

  5. Cow (Bovine) Monoclonal RASA1 Primary Antibody für ICC, IF - ABIN266005 : Muto, Yi, Harrison, Dávalos, Fancher, Ziegler, Feigel, Kondo, Nishibe, Sessa, Dardik: Eph-B4 prevents venous adaptive remodeling in the adult arterial environment. in The Journal of experimental medicine 2011 (PubMed)

Weitere Antikörper gegen RASA1 Interaktionspartner

Human RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Interaktionspartner

  1. results indicate that, mTOR (zeige FRAP1 Antikörper), Bad, or Survivin (zeige BIRC5 Antikörper) are not required for p120 RasGAP fragment N to protect cells from cell death; conclude that downstream targets of Akt (zeige AKT1 Antikörper) other than mTORC1, Bad, or survivin (zeige BIRC5 Antikörper) mediate fragment N-induced protection or that several Akt (zeige AKT1 Antikörper) effectors can compensate for each other to induce the pro-survival fragment N-dependent responses

  2. The interaction between RASA1 and EPHB4 (zeige EPHB4 Antikörper) is an indication of the major cause of capillary malformation with arteriovenous malformation.

  3. Low RASA1 expression is associated with Triple-Negative Breast Cancer.

  4. QKI-5 (zeige QKI Antikörper) stabilized RASA1 mRNA via directly binding to the QKI (zeige QKI Antikörper) response element region of RASA1, which in turn prevented the activation of the Ras-MAPK (zeige MAPK1 Antikörper) signaling pathway, suppressed cellular proliferation and induced cell cycle arrest.

  5. Data show that patients with low level of Ras GTPase-activating protein 1 (RASA1) expression correlated with a significantly poorer survival compared to those with high level of RASA1 expression.

  6. Results show that oncogenic KRAS can activate Rho through miR-31-mediated regulation of RASA1 indicating miR-31 acts as a KRAS effector to modulate invasion and migration in pancreatic cancer.

  7. PTP1B (zeige PTPN1 Antikörper) dephosphorylates PITX1 (zeige PITX1 Antikörper) to weaken its protein stability and the transcriptional activity for p120RasGAP gene expression

  8. Data suggest that, in response to netrin-1 (zeige NTN1 Antikörper)/netrin receptor (DCC (zeige DCC Antikörper)) signaling, p120RasGAP is recruited to growth cones and supports axon outgrowth; p120RasGAP Src (zeige SRC Antikörper) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  9. Maternal and fetal capillary malformation-arteriovenous malformation due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis have been found.

  10. This is the second largest study on isolated, non-syndromic Port-wine stain; data suggest that GNAQ (zeige GNAQ Antikörper) is the main genetic determinant in this condition. Moreover, isolated port-wine stains are distinct from capillary malformations seen in RASA1 disorders.

Cow (Bovine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Interaktionspartner

  1. The data suggest that nitrosylation of H-Ras (zeige HRAS Antikörper) rearranges the adsorptive potential and intrinsic GTPase (zeige RACGAP1 Antikörper) activity of H-Ras (zeige HRAS Antikörper) through modification of C-terminal cysteines of molecule.

Mouse (Murine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Interaktionspartner

  1. results indicate that, mTOR (zeige FRAP1 Antikörper), Bad, or Survivin (zeige BIRC5 Antikörper) are not required for p120 RasGAP fragment N to protect cells from cell death; conclude that downstream targets of Akt (zeige AKT1 Antikörper) other than mTORC1, Bad, or survivin (zeige BIRC5 Antikörper) mediate fragment N-induced protection or that several Akt (zeige AKT1 Antikörper) effectors can compensate for each other to induce the pro-survival fragment N-dependent responses

  2. RASA1 catalytic activity is essential for the function and development of lymphatic vessel valves.

  3. These results indicate that the caspase-3 (zeige CASP3 Antikörper)/p120 RasGAP stress-sensing module impacts on carcinogen-induced liver cancer incidence but not sufficiently so as to affect overall survival.

  4. Double-deficient RASA1-neurofibromin 1 (zeige NF1 Antikörper) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (zeige NOTCH1 Antikörper) gene.

  5. Rasa1 may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model

  6. Regulation of Rasa1 translation by miR (zeige MLXIP Antikörper)-132 was seen in severed axons, demonstrating local function within the axon.

  7. RASA1 mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS subject and in the animal model.

  8. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 (zeige D4S234E Antikörper) GTPase activating protein 1 (RASA1)

  9. 14-3-3 (zeige YWHAQ Antikörper) negatively regulates the RGC downstream of the PI3-kinase (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling pathway

  10. Caspase-3 (zeige CASP3 Antikörper) is a stress intensity sensor that controls cell fate by either initiating a RasGAP cleavage-dependent cell resistance program or a cell suicide response mediated by akt (zeige AKT1 Antikörper).

RASA1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.

Alternative names and synonyms associated with RASA1

  • vacuolar peduncle (vap) Antikörper
  • RAS p21 protein activator (GTPase activating protein) 1 (RASA1) Antikörper
  • RAS p21 protein activator (GTPase activating protein) 1 (Rasa1) Antikörper
  • RAS p21 protein activator 1 (Rasa1) Antikörper
  • CG9209 Antikörper
  • CM-AVM Antikörper
  • CMAVM Antikörper
  • D-RasGAP Antikörper
  • Dmel\\CG9209 Antikörper
  • Gap Antikörper
  • GAPX Antikörper
  • p120GAP Antikörper
  • p120RASGAP Antikörper
  • PKWS Antikörper
  • RAS-GAP Antikörper
  • Rasa Antikörper
  • RASGAP Antikörper

Bezeichner auf Proteinebene für RASA1

CG9209-PA , CG9209-PB , CG9209-PC , CG9209-PD , Ras GTPase-activating protein , vacuolar peduncule , vacuolar pedunculi , vap-PA , vap-PB , vap-PC , vap-PD , ras GTPase-activating protein 1 , triphosphatase-activating protein , GAP , GTPase-activating protein , RAS p21 protein activator (GTPase activating protein RAS p21) , p120GAP , rasGAP , RAS p21 protein activator 1 , p120-rasGAP

GENE ID SPEZIES
32569 Drosophila melanogaster
5921 Homo sapiens
282032 Bos taurus
25676 Rattus norvegicus
427327 Gallus gallus
479158 Canis lupus familiaris
100627579 Sus scrofa
218397 Mus musculus
Ausgewählte Anbieter für anti-RASA1 (RASA1) Antikörper
Haben Sie etwas anderes gesucht?