Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 20-650) peptide (His tag)

Produktnummer ABIN934998

Kurzübersicht für Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 20-650) peptide (His tag) (ABIN934998)

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktdetails

Protein-Typ: Recombinant

Protein Region: AA 20-650

Aufreinigungstag / Konjugat: Dieses GRP78 Peptid ist gelabelt mit His tag.

Sequenz: MEEDKKEDVG TVVGIDLGTT YSCVGVFKNG RVEIIANDQG NRITPSYVAF TPEGERLIGD AAKNQLTSNP ENTVFDAKRL IGRTWNDPSV QQDIKFLPFK VVEKKTKPYI QVDIGGGQTK TFAPEEISAM VLTKMKETAE AYLGKKVTHA VVTVPAYFND AQRQATKDAG TIAGLNVMRI INEPTAAAIA YGLDKREGEK NILVFDLGGG TFDVSLLTID NGVFEVVATN GDTHLGGEDF DQRVMEHFIK LYKKKTGKDV RKDNRAVQKL RREVEKAKRA LSSQHQARIE IESFYEGEDF SETLTRAKFE ELNMDLFRST MKPVQKVLED SDLKKSDIDE IVLVGGSTRI PKIQQLVKEF FNGKEPSRGI NPDEAVAYGA AVQAGVLSGD QDTGDLVLLD VCPLTLGIET VGGVMTKLIP RNTVVPTKKS QIFSTASDNQ PTVTIKVYEG ERPLTKDNHL LGTFDLTGIP PAPRGVPQIE VTFEIDVNGI LRVTAEDKGT GNKNKITITN DQNRLTPEEI ERMVNDAEKF AEEDKKLKER IDTRNELESY AYSLKNQIGD KEKLGGKLSS EDKETMEKAV EEKIEWLESH QDADIEDFKA KKKELEEIVQ PIISKLYGSA GPPPTGEEDT AELEHHHHHH

Produktmerkmale: Purified recombinant Human BIP protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Reinheit: > 90 % pure

Anwendungsinformationen

Applikationshinweise: BIP protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris, pH 8.0, containing 10 % glycerol.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Hintergrund: Binding immunoglobulin protein (BiP) belongs to the family of ~70 kDa heat shock proteins (HSP 70). It is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis. Recombinant human BIP protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Binding immunoglobulin protein protein, Heat Shock 70kDa Protein 5 protein, glucose-regulated protein 78kD protein, Immunoglobulin Heavy Chain Binding Protein., Endoplasmic reticulum lumenal Ca2+ binding protein grp78 protein, GRP78 protein, BIP protein, HSPA 5 protein, Binding immunoglobulin protein 78 kDa glucose regulated protein protein, HSPA5 protein, MIF2 protein, heat shock 70kDa protein 5 protein, GRP78 protein, FLJ26106 protein, GRP 78 protein, Glucose Regulated Protein 78kDa protein

Molekulargewicht: 71 kDa (640 AA)