VOPP1 Protein (AA 82-172) (His tag)

Produktnummer ABIN7279458

Dieses Recombinant VOPP1-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für VOPP1 Protein (AA 82-172) (His tag) (ABIN7279458)

Target: VOPP1 (Vesicular, Overexpressed in Cancer, Prosurvival Protein 1 (VOPP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 82-172

Aufreinigungstag / Konjugat: Dieses VOPP1 Protein ist gelabelt mit His tag.

Sequenz: RRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK

Produktmerkmale: VOPP1, 82-172aa, Human, His tag, E.coli

Aufreinigung: > 90% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT, 30 % glycerol, 0.2M NaCl

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: VOPP1 (Vesicular, Overexpressed in Cancer, Prosurvival Protein 1 (VOPP1))

Andere Bezeichnung: VOPP1

Hintergrund: Vesicular, overexpressed in cancer, prosurvival protein 1 (VOPP1), also known as Glioblastoma-amplified secreted protein (GASP), has been previously shown to be over-expressed in human glioblastoma multiforme and squamous cell carcinoma. VOPP1 is a key regulator of NF-kappaB signaling, and that high-level, amplification-mediated VOPP1 expression, such as that occurring in tumors with amplified EGFR, could contribute to resistance to apoptosis. Recombinant human VOPP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 12 kDa (112aa) confirmed by MALDI-TOF

NCBI Accession: NP_110423