CCL1 Protein (AA 24-96) (His tag)

Produktnummer ABIN667883

Dieses Recombinant CCL1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für CCL1 Protein (AA 24-96) (His tag) (ABIN667883)

Target: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 85 %

Produktdetails

Proteineigenschaft: AA 24-96

Aufreinigungstag / Konjugat: Dieses CCL1 Protein ist gelabelt mit His tag.

Sequenz: MGSSHHHHHH SSGLVPRGSH MKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK

Produktmerkmale: CCL1, 24-96aa, Human, His tag, E.coli

Aufreinigung: > 85% by SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 7.5) containing 2 mM DTT, 10 % glycerol, 50 mM NaCl

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Andere Bezeichnung: CCL1/I-309

Hintergrund: CCL1 (chemokine C-C motif ligand 1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. unlike the other members of the C-C family, CCL1 does not induce chemotaxis in natural killer (NK) cells. Recombinant human CCL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Molekulargewicht: 10.8 kDa (94aa) confirmed by MALDI-TOF

NCBI Accession: NP_002972