SNRPF Protein (AA 1-86) (His tag)

Produktnummer ABIN667847

Dieses Recombinant SNRPF-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für SNRPF Protein (AA 1-86) (His tag) (ABIN667847)

Target: SNRPF (Small Nuclear Ribonucleoprotein Polypeptide F (SNRPF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 1-86

Aufreinigungstag / Konjugat: Dieses SNRPF Protein ist gelabelt mit His tag.

Sequenz: MGSSHHHHHH SSGLVPRGSH MSLPLNPKPF LNGLTGKPVM VKLKWGMEYK GYLVSVDGYM NMQLANTEEY IDGALSGHLG EVLIRCNNVL YIRGVEEEEE DGEMRE

Produktmerkmale: SNRPF, 1-86aa, Human, His tag, E.coli

Aufreinigung: > 95% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT, 10 % glycerol, 1 mM EDTA

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SNRPF (Small Nuclear Ribonucleoprotein Polypeptide F (SNRPF))

Andere Bezeichnung: SNRPF

Hintergrund: Small nuclear ribonucleoprotein polypeptide F, also known SNRPF, belongs to the snRNP Sm proteins family. There are at least seven isoforms, E, F, G, D1, D2, D3 and B/B. This class of common proteins plays an essential role in the biogenesis of the snRNPs. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE). SNRPF aid in the cytoplasmic construction of the usnRNPs by binding to aconserved Sm site on usnRNA and forming a stable snRNP core complex. Recombinant human SNRPF protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 11.8 kDa (106aa) confirmed by MALDI-TOF

NCBI Accession: NP_003086

Pathways: Ribonucleoprotein Complex Subunit Organization