HAT1 protein (HIS)

Name: HAT1

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Konjugat: HIS

Applikation: SDS-PAGE (SDS)

Produktnummer: ABIN667772

Produktbeschreibung

Produktmerkmale: HAT1, 20-341aa, Human, His tag, E.coli

Format: Liquid

Beschreibung: HAT1, also known as histone acetyltransferase 1, is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Recombinant HAT1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: KAT1, Histone acetyltransferase 1 HAT 1, Histidine aminotransferase 1, Histone acetyltransferase type B catalytic subunit. NCBI no.: NP_003633

Molekulargewicht: 40.1 kDa (343aa), confirmed by MALDI-TOF.

Anwendungen

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Reinheit: > 90% by SDS-PAGE

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT.

Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bilder

HAT1 protein (HIS)