CCL14 Protein (AA 20-93) (His tag)

Produktnummer ABIN667363

Recombinant CCL14-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für CCL14 Protein (AA 20-93) (His tag) (ABIN667363)

Target: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 20-93

Aufreinigungstag / Konjugat: Dieses CCL14 Protein ist gelabelt mit His tag.

Sequenz: MGSSHHHHHH SSGLVPRGSH MTKTESSSRG PYHPSECCFT YTTYKIPRQR IMDYYETNSQ CSKPGIVFIT KRGHSVCTNP SDKWVQDYIK DMKEN

Produktmerkmale: CCL14, 20-93aa, Human, His tag, E.coli

Aufreinigung: > 95% by SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Andere Bezeichnung: CCL14/HCC-1

Hintergrund: CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1alpha. It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1 (9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5. Recombinant human CCL14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Molekulargewicht: 10.9 kDa (95aa) confirmed by MALDI-TOF

NCBI Accession: NP_116739