V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (pTry207) protein (HIS)

Name: V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL)

Synonyme: Crkol, AA589403, AI325100, 1110025F07Rik, CRKL, MGC63469, zgc:63469, wu:fa55g05, wu:fj60e01

Epitope: pTry207

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Konjugat: HIS

Applikation: SDS-PAGE (SDS)

Produktnummer: ABIN667314

Produktbeschreibung

Produktmerkmale: CRKL, 1-303aa, Human, His tag, E.coli

Format: Liquid

Beschreibung: CRKL is a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substitutete of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and has oncogenic potential. Recombinant human CRKL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Crk-like protein,. NCBI no.: NP_005198

Molekulargewicht: 35.9 kDa (323aa), confirmed by MALDI-TOF

Anwendungen

Konzentration: 1 mg/ml (determined by Bradford assay)

Reinheit: > 90 % by SDS – PAGE

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.

Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bilder

V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (pTry207) protein (HIS)