PDRG1 Protein (AA 1-133) (His tag)

Produktnummer ABIN667266

Dieses Recombinant PDRG1-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für PDRG1 Protein (AA 1-133) (His tag) (ABIN667266)

Target: PDRG1 (P53 and DNA-Damage Regulated 1 (PDRG1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 1-133

Aufreinigungstag / Konjugat: Dieses PDRG1 Protein ist gelabelt mit His tag.

Sequenz: MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG

Produktmerkmale: PDRG1, 1-133aa, Human, His tag, E.coli

Aufreinigung: > 90% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 5 mM DTT, 20 % glycerol

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: PDRG1 (P53 and DNA-Damage Regulated 1 (PDRG1))

Andere Bezeichnung: PDRG1

Hintergrund: PDRG1, also known as PDRG or C20orf126, is a 133 amino acid protein that localizes to the cytoplasm and belongs to the prefoldin subunit beta family. Expressed predominately in normal testicular tissue, PDRG1 is functionally induced by ultraviolet light and is thought to play a role in chaperone-mediated protein folding, possibly playing a role in cellular degradation. It is associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Recombinant human PDRG1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 17.6 kDa (153aa) confirmed by MALDI-TOF

NCBI Accession: NP_110442