SBDS Protein (AA 1-250) (His tag)

Produktnummer ABIN667248

Dieses Recombinant SBDS-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für SBDS Protein (AA 1-250) (His tag) (ABIN667248)

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 1-250

Aufreinigungstag / Konjugat: Dieses SBDS Protein ist gelabelt mit His tag.

Sequenz: MSIFTPTNQI RLTNVAVVRM KRAGKRFEIA CYKNKVVGWR SGVEKDLDEV LQTHSVFVNV SKGQVAKKED LISAFGTDDQ TEICKQILTK GEVQVSDKER HTQLEQMFRD IATIVADKCV NPETKRPYTV ILIERAMKDI HYSVKTNKST KQQALEVIKQ LKEKMKIERA HMRLRFILPV NEGKKLKEKL KPLIKVIESE DYGQQLEIVC LIDPGCFREI DELIKKETKG KGSLEVLNLK DVEEGDEKFE

Produktmerkmale: SBDS, 1-250aa, Human, His tag, E.coli

Aufreinigung: > 95% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 2 mM DTT, 50 mM NaCl, 0.1 mM EDTA

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Andere Bezeichnung: SBDS

Hintergrund: Ribosome maturation protein SBDS is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. It may be involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Shwachman-Diamond syndrome is a rare autosomal recessive disorder caused by mutations in the SBDS gene. Recombinant human SBDS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 30.9 kDa (270aa) confirmed by MALDI-TOF

NCBI Accession: NP_057122

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly