HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) protein (HIS)

Name: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Synonyme: CC3, TIP30, SDR44U1, FLJ26963, Cc3, Tip30, AW111545, tip30, fb15b04, wu:fb15b04, MGC115485, htatip2, MGC89074, HTATIP2, MGC129016

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Konjugat: HIS

Applikation: SDS-PAGE (SDS)

Produktnummer: ABIN667152

Produktbeschreibung

Produktmerkmale: HTATIP2, 1-242aa, Human, His tag, E.coli

Format: Liquid

Beschreibung: HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. Recombinant human HTATIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CC3, TIP30, SDR44U1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30. NCBI no.: AAH15358

Molekulargewicht: 29.3 kDa (262aa), confirmed by MALDI-TOF

Anwendungen

Konzentration: 1 mg/ml (determined by Bradford assay)

Reinheit: > 95 % by SDS- PAGE

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT

Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bilder

HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) protein (HIS)