MAGEA4 Protein (AA 1-317) (His tag)

Produktnummer ABIN667021

Recombinant MAGEA4-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für MAGEA4 Protein (AA 1-317) (His tag) (ABIN667021)

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 1-317

Aufreinigungstag / Konjugat: Dieses MAGEA4 Protein ist gelabelt mit His tag.

Sequenz: MSSEQKSQHC KPEEGVEAQE EALGLVGAQA PTTEEQEAAV SSSSPLVPGT LEEVPAAESA GPPQSPQGAS ALPTTISFTC WRQPNEGSSS QEEEGPSTSP DAESLFREAL SNKVDELAHF LLRKYRAKEL VTKAEMLERV IKNYKRCFPV IFGKASESLK MIFGIDVKEV DPTSNTYTLV TCLGLSYDGL LGNNQIFPKT GLLIIVLGTI AMEGDSASEE EIWEELGVMG VYDGREHTVY GEPRKLLTQD WVQENYLEYR QVPGSNPARY EFLWGPRALA ETSYVKVLEH VVRVNARVRI AYPSLREAAL LEEEEGV

Produktmerkmale: MAGEA4, 1-317aa, Human, His tag, E.coli

Aufreinigung: > 90% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Andere Bezeichnung: MAGEA4

Hintergrund: MAGEA4 is a member of the MAGEA family, which directs the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes (CTL). The function of MAGEA4 is not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. This protein is expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Recombinant human MAGEA4, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Molekulargewicht: 37 kDa (337aa) confirmed by MALDI-TOF