CDK2AP1 Protein (AA 1-115) (His tag)

Produktnummer ABIN666944

Dieses Recombinant CDK2AP1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für CDK2AP1 Protein (AA 1-115) (His tag) (ABIN666944)

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 1-115

Aufreinigungstag / Konjugat: Dieses CDK2AP1 Protein ist gelabelt mit His tag.

Sequenz: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS

Produktmerkmale: CDK2AP1, 1-115aa, Human, His tag, E. coli

Aufreinigung: > 95% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 50 % glycerol, 2 mM DTT

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Andere Bezeichnung: CDK2AP1

Hintergrund: CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant CDK2AP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 16.6 kDa (152aa) confirmed by MALDI-TOF

NCBI Accession: NP_004633