CCL13 Protein (AA 24-98) (His tag)

Produktnummer ABIN666792

Dieses Recombinant CCL13-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für CCL13 Protein (AA 24-98) (His tag) (ABIN666792)

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 24-98

Aufreinigungstag / Konjugat: Dieses CCL13 Protein ist gelabelt mit His tag.

Sequenz: MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK AHTLKT

Produktmerkmale: CCL13, 24-98aa, Human, His tag, E.coli

Aufreinigung: > 90% by SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol, 0.1M NaCl,1 mM DTT

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Andere Bezeichnung: CCL13/MCP-4

Hintergrund: CCL13 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. It can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha. Recombinant human CCL13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 10.8 kDa (96aa) confirmed by MALDI-TOF

NCBI Accession: NP_005399

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Phosphorylierungen bei SARS-CoV-2 Infektion