OAS1 protein (HIS)

Name: OAS1

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Konjugat: HIS

Applikation: SDS-PAGE (SDS)

Produktnummer: ABIN666789

Produktbeschreibung

Produktmerkmale: OAS1, 1-364 aa, Human, His-tagged, Recombinant, E.coli

Format: Liquid

Beschreibung: OAS1 is an enzyme included in the 2’,5’-oligoadenylate synthase family. This enzyme is induced by interferons and uses adenosine triphosphate in 2’-specific nucleotidyl transfer reactions to synthesize 2’,5’-oligoadenylates(2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. OAS1 may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. Recombinant OAS1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: IFI-4, OIAS, OIASI, 2’,5’-oligoadenylate synthetase 1, isoform2 (2 5')oligo(A) synthetase 1, 2' 5' oligo A synthetase 1, 2 5 Oligoadenylate Synthetase 1, 2 5A synthetase 1, 2' 5' oligoadenylate synthetase 1, 2' 5' oligoisoadenylate synthetase 1, 2'5' oligoadenylate synthetase 1, 2'5' oligoisoadenylate synthetase 1, p46/p42 OAS, 2'5' oligo A synthetase 1, E18/E16, IFI 4, IFI4, OAS 1,. NCBI no.: NP_002525

Molekulargewicht: 43.9 kDa (384aa), confirmed by MALDI-TOF.

Anwendungen

Konzentration: 1 mg/ml (determined by Bradford assay)

Reinheit: > 95% by SDS-PAGE

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol and 1mM DTT.

Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bilder

OAS1 protein (HIS)