SAP18 Protein (AA 20-172) (His tag)

Produktnummer ABIN666775

Recombinant SAP18-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für SAP18 Protein (AA 20-172) (His tag) (ABIN666775)

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 20-172

Aufreinigungstag / Konjugat: Dieses SAP18 Protein ist gelabelt mit His tag.

Sequenz: MAVESRVTQE EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT WMDATLKELT SLVKEVYPEA RKKGTHFNFA IVFTDVKRPG YRVKEIGSTM SGRKGTDDSM TLQSQKFQIG DYLDIAITPP NRAPPPSGRM RPY

Produktmerkmale: SAP18, 20- 172 aa, Human, His-tagged, Recombinant, E.coli

Aufreinigung: > 90% by SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 0.1M NaCl, 30 % glycerol, 1 mM DTT

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Andere Bezeichnung: SAP18

Hintergrund: SAP18, also known as Sin3A-associated protein, is component of the histone deacetylase complex that plays an important role in the regulation of eukaryotic gene expression. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. It also has been shown to play a key role in gene-specific recruitment of the HDAC complex by a number of transcription factors including Gli, GAGA, and Bicoid. Recombinant SAP18 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 19.7 kDa (173aa) confirmed by MALDI-TOF

NCBI Accession: NP_005861