CSTB Protein (AA 1-98) (His tag)

Produktnummer ABIN666707

Dieses Recombinant CSTB-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für CSTB Protein (AA 1-98) (His tag) (ABIN666707)

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 1-98

Aufreinigungstag / Konjugat: Dieses CSTB Protein ist gelabelt mit His tag.

Sequenz: MMCGAPSATQ PATAETQHIA DQVRSQLEEK ENKKFPVFKA VSFKSQVVAG TNYFIKVHVG DEDFVHLRVF QSLPHENKPL TLSNYQTNKA KHDELTYF

Produktmerkmale: CSTB, 1-98 aa, Human, His-tagged, Recombinant, E.coli

Aufreinigung: > 95% by SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 50 mM NaCl

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Andere Bezeichnung: Cystatin B

Hintergrund: CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus. Recombinant CSTB, fused to His-tag, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 13 kDa (118aa) confirmed by MALDI-TOF

NCBI Accession: NP_000091

Pathways: Response to Water Deprivation