PAGR1 Protein (AA 1-254) (His tag)

Produktnummer ABIN666650

Dieses Recombinant PAGR1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für PAGR1 Protein (AA 1-254) (His tag) (ABIN666650)

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 85 %

Produktdetails

Proteineigenschaft: AA 1-254

Aufreinigungstag / Konjugat: Dieses PAGR1 Protein ist gelabelt mit His tag.

Sequenz: MGSSHHHHHH SSGLVPRGSH MSLARGHGDT AASTAAPLSE EGEVTSGLQA LAVEDTGGPS ASAGKAEDEG EGGREETERE GSGGEEAQGE VPSAGGEEPA EEDSEDWCVP CSDEEVELPA DGQPWMPPPS EIQRLYELLA AHGTLELQAE ILPRRPPTPE AQSEEERSDE EPEAKEEEEE KPHMPTEFDF DDEPVTPKDS LIDRRRTPGS SARSQKREAR LDKVLSDMKR HKKLEEQILR TGRDLFSLDS EDPSPASPPL RSSGSSLFPR QRKY

Produktmerkmale: PA1, 1-254aa, Human, His tag, E.coli

Aufreinigung: > 85% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 2 mM DTT, 0.1M NaCl.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Andere Bezeichnung: PA1/PAGR1

Hintergrund: PA1 is a component of a Set1-like multiprotein histone methyltransferase complex. It interacts with PAXIP1/PTIP, the interaction is direct and is required for the association with the rest of the PTIP complex. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis. Recombinant human PA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 29.9 kDa (274aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

NCBI Accession: NP_078792