anti-TRAF3IP2 (TRAF3IP2) Antikörper

anti-TRAF3 Interacting Protein 2 Antikörper (TRAF3IP2)
Auf finden Sie aktuell 129 TRAF3 Interacting Protein 2 (TRAF3IP2) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF3IP2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 145 TRAF3IP2 Produkte verfügbar.
Act1, AI429613, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, MGC134034, PSORS13, RGD1304768, t3jam, TRAF3IP2
Alle Antikörper anzeigen Gen GeneID UniProt
TRAF3IP2 361857  
TRAF3IP2 10758 O43734
TRAF3IP2 103213  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TRAF3IP2 (TRAF3IP2) Antikörper

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anti-Rat (Rattus) TRAF3IP2 Antikörper:

anti-Human TRAF3IP2 Antikörper:

anti-Mouse (Murine) TRAF3IP2 Antikörper:

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Am meisten referenzierte anti-TRAF3IP2 Antikörper

  1. Human Polyclonal TRAF3IP2 Primary Antibody für IHC (p), SimWes - ABIN4361705 : Valente, Yoshida, Clark, Delafontaine, Siebenlist, Chandrasekar: Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling. in Free radical biology & medicine 2013 (PubMed)
    Zeige alle 6 Referenzen für 4361705

  2. Human Polyclonal TRAF3IP2 Primary Antibody für ELISA, WB - ABIN4361709 : Qian, Liu, Hartupee, Altuntas, Gulen, Jane-Wit, Xiao, Lu, Giltiay, Liu, Kordula, Zhang, Vallance, Swaidani, Aronica, Tuohy, Hamilton, Li: The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. in Nature immunology 2007 (PubMed)

  3. Human Polyclonal TRAF3IP2 Primary Antibody für WB - ABIN2472996 : Leonardi, Chariot, Claudio, Cunningham, Siebenlist: CIKS, a connection to Ikappa B kinase and stress-activated protein kinase. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)

Weitere Antikörper gegen TRAF3IP2 Interaktionspartner

Human TRAF3 Interacting Protein 2 (TRAF3IP2) Interaktionspartner

  1. AP1 (zeige FOSB Antikörper) binding sites were enriched upstream of genes up-regulated by TRAF3IP2 silencing. Correspondingly, nuclear expression of FosB (zeige FOSB Antikörper) and Fra1 (zeige FOSL1 Antikörper) was increased in TRAF3IP2-silenced cells. Many genes involved in host defense were induced by IL-17 (zeige IL17A Antikörper) in a TRAF3IP2-dependent fashion.

  2. TRAF3IP2 SNP rs33980500 associated with no achievement of low disease activity nor remission at 6 months

  3. the first report to describe a non-adaptor function of Act1 by directly binding to the promoter region of IL-17A (zeige IL17A Antikörper) responsive genes and directly regulate their transcription.

  4. ACT1 is an essential adaptor molecule of Il-17 (zeige IL17A Antikörper)-induced expression of inflammation-related gene targets.

  5. Both the ACT-1 assay and the MAdCAM-1 (zeige MADCAM1 Antikörper) assay demonstrated acceptable reproducibility and repeatability. The assays were sufficiently stable to allow for clinical use. During clinical testing the assays demonstrated that vedolizumab was able to saturate peripheral cells at all doses tested.

  6. A G/G genotype of rs766748 in IL-17F (zeige IL17F Antikörper), and a C/C or C/A genotype of rs1883136 in TRAF3IP2.

  7. The suppressive effects of miR (zeige MLXIP Antikörper)-30a were mediated by directly targeting Traf3ip2 mRNA

  8. TRAF3IP2 may play a causal role in aldosterone-induced adverse cardiac remodeling in vivo.

  9. Single nucleotide polymorphisms in RBPJ (zeige RBPJ Antikörper), IL1R1 (zeige IL1RN Antikörper), REV3L (zeige REV3L Antikörper), TRAF3IP2, IRF1 (zeige IRF1 Antikörper) and ICOS (zeige CTLA4 Antikörper) showed association with rheumatoid arthritis in black South Africans.

  10. A variant (rs76228616 SNP) in TRAF3IP2 gene could be involved in susceptibility to Steven-Johnson Syndrome.

Mouse (Murine) TRAF3 Interacting Protein 2 (TRAF3IP2) Interaktionspartner

  1. ameliorating myocardial damage by targeting TRAF3IP2 appears to be more effective to inhibiting its downstream signaling intermediates NF-kappaB (zeige NFKB1 Antikörper) and JNK (zeige MAPK8 Antikörper). Therefore, TRAF3IP2 could be a potential therapeutic target in ischemic heart disease

  2. these results demonstrate that overexpression of TRAF3IP2 in male mice is sufficient to induce myocardial hypertrophy, cardiac fibrosis, and contractile dysfunction.

  3. using massively parallel reporter assays, we dissect the enhancer activity of three liver eExons (SORL1 (zeige SORL1 Antikörper) exon 17, TRAF3IP2 exon 2, PPARG (zeige PPARG Antikörper) exon 6) at single nucleotide resolution in the mouse liver

  4. TRAF3IP2 is a critical intermediate in IL-18 (zeige IL18 Antikörper)-induced cardiac fibroblast migration and differentiation in vitro.

  5. Our results support the important role of Act1 in the regulation of self-reactive B cells and reveal how Act1 functions to prevent the production of autoantibodies.

  6. These results demonstrate for the first time that AOPPs induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent

  7. CIKS knockdown inhibited high glucose-induced IKKbeta (zeige IKBKB Antikörper) and JNK (zeige MAPK8 Antikörper) phosphorylation, p65 (zeige NFkBP65 Antikörper) and c-Jun (zeige JUN Antikörper) nuclear translocation, and NF-kappaB (zeige NFKB1 Antikörper)- and AP-1 (zeige JUN Antikörper)-dependent proinflammatory cytokine, chemokine (zeige CCL1 Antikörper), and adhesion molecule (zeige NCAM1 Antikörper) expression.

  8. The findings define a new role for the IKK-related kinases in suppressing IL-17-mediated NF-kappaB activation through TRAF6-dependent Act1 phosphorylation.

  9. Data show that deletion of the CC' loop from Act1 or IL-17RA (zeige IL17RA Antikörper) abolished the interaction between both proteins.

  10. our findings indicate that Act1 expression in T cells is required for cellular and humoral Th2-mediated allergic responses and the development of airway hyperresponsiveness

TRAF3IP2 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Alternative names and synonyms associated with TRAF3IP2

  • Traf3 interacting protein 2 (Traf3ip2) Antikörper
  • TRAF3 interacting protein 2 (TRAF3IP2) Antikörper
  • adapter protein CIKS-like (LOC100467029) Antikörper
  • adapter protein CIKS-like (LOC100480036) Antikörper
  • adapter protein CIKS-like (LOC100490063) Antikörper
  • TRAF3 interacting protein 2 (traf3ip3) Antikörper
  • TRAF3 interacting protein 2 (LOC100226375) Antikörper
  • TRAF3 interacting protein 2 (Traf3ip2) Antikörper
  • Act1 Antikörper
  • AI429613 Antikörper
  • C6orf2 Antikörper
  • C6orf4 Antikörper
  • C6orf5 Antikörper
  • C6orf6 Antikörper
  • CIKS Antikörper
  • MGC134034 Antikörper
  • PSORS13 Antikörper
  • RGD1304768 Antikörper
  • t3jam Antikörper
  • TRAF3IP2 Antikörper

Bezeichner auf Proteinebene für TRAF3IP2

adapter protein CIKS , TRAF3 interacting protein 2 , adapter protein CIKS-like , NFkB-activating protein ACT1 , connection to IKK and SAPK/JNK , nuclear factor NF-kappa-B activator 1

361857 Rattus norvegicus
100390719 Callithrix jacchus
100439347 Pongo abelii
100467029 Ailuropoda melanoleuca
100473939 Ailuropoda melanoleuca
100480036 Ailuropoda melanoleuca
100490063 Xenopus (Silurana) tropicalis
421752 Gallus gallus
494853 Xenopus laevis
549319 Xenopus (Silurana) tropicalis
616801 Bos taurus
697530 Macaca mulatta
741209 Pan troglodytes
100226375 Taeniopygia guttata
10758 Homo sapiens
103213 Mus musculus
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