A synthetic peptide for use as a blocking control in assays to test for specificity of PCSK2 antibody, Alternative Names: PCSK2 control peptide, PCSK2 antibody Blocking Peptide, Anti-PCSK2 Blocking Peptide, proprotein convertase subtilisin/kexin type 2 Blocking Peptide, NEC2 Blocking Peptide, PC2 Blocking Peptide, SPC2 Blocking Peptide, PCSK2, PCSK-2, PCSK 2, PCSK-2 Blocking Peptide, PCSK 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PCSK2
(Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
Hintergrund
This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.