A synthetic peptide for use as a blocking control in assays to test for specificity of SGMS2 antibody, Alternative Names: SGMS2 control peptide, SGMS2 antibody Blocking Peptide, Anti-SGMS2 Blocking Peptide, Sphingomyelin Synthase 2 Blocking Peptide, MGC26963 Blocking Peptide, SMS2 Blocking Peptide, SGMS2, SGMS-2, SGMS 2, SGMS-2 Blocking Peptide, SGMS 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Sphingomyelin Synthase 2 (SGMS2)
Hintergrund
SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognises the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognised efficiently as a substrate. SGMS2 does not function strictly as a SM synthase.