A synthetic peptide for use as a blocking control in assays to test for specificity of HLA-DQA2 antibody, Alternative Names: HLA-DQA2 control peptide, HLA-DQA2 antibody Blocking Peptide, Anti-HLA-DQA2 Blocking Peptide, Major Histocompatibility Complex Class Ii Dq Alpha 2 Blocking Peptide, DQ alpha Blocking Peptide, HLA-DXA Blocking Peptide
HLA-DQA2
Reaktivität: Human
Wirt: Synthetic
BP, BI
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
HLA-DQA2
(Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
Hintergrund
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognised by CD4 T-cells.