V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog ELISA Kits (HRAS)
Auf finden Sie aktuell 17 V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) ELISA Kits von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HRAS Antikörper (143) und HRAS Proteine (19) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 190 HRAS Produkte verfügbar.
AI929937, C-BAS/HAS, c-H-ras, c-Ha-ras, C-HA-RAS1, c-rasHa, CTLO, H-ras, H-RASIDX, Ha-ras, HAMSV, Harvey-ras, hras, Hras-1, HRAS1, K-ras, Ki-ras, Kras-2, Kras2, N-RAS, p21B, ras, RASH1, zgc:110250

Weitere ELISA Kits für HRAS Interaktionspartner

Cow (Bovine) V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Interaktionspartner

  1. Data demonstrate that H-Ras activation is important in the activation of the specific signaling events leading to the accelerated retinal capillary cell apoptosis in hyperglycemic conditions.

  2. Activation of H-Ras and its downstream signaling pathway in the retina and its vasculature could be under the control of superoxide, and H-Ras activation in diabetes can be prevented by inhibiting superoxide accumulation.

  3. Thrombospondin 1 (zeige THBS1 ELISA Kits), fibronectin (zeige FN1 ELISA Kits), and vitronectin (zeige VTN ELISA Kits) are differentially dependent upon RAS, ERK1/2 (zeige MAPK1/3 ELISA Kits), and p38 (zeige MAPK14 ELISA Kits) for induction of vascular smooth muscle cell chemotaxis.

Zebrafish V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Interaktionspartner

  1. Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish

Human V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Interaktionspartner

  1. Knockdown of forkhead Box M1 (FoxM1 (zeige FOXM1 ELISA Kits)) reduced Prx (zeige PRDX6 ELISA Kits) II levels in H-ras(G12V)-hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)) cells, indicating FoxM1 (zeige FOXM1 ELISA Kits) as a direct transcription factor of Prx (zeige PRDX6 ELISA Kits) II in HCC (zeige FAM126A ELISA Kits).

  2. we found that ectopic expression of oncogenic KRas and HRas in cells resulted in elevated CIB1 (zeige CIB1 ELISA Kits) expression. We previously described the Ca(2 (zeige CA2 ELISA Kits)+)-myristoyl switch function of CIB1 (zeige CIB1 ELISA Kits), and its ability to facilitate agonist-induced plasma membrane localisation of sphingosine kinase 1 (SK1 (zeige SPHK1 ELISA Kits)), a location where SK1 (zeige KCNN1 ELISA Kits) is known to elicit oncogenic signalling.

  3. Data suggest that isoform-specific sequences in the allosteric lobes of HRAS, KRAS, and NRAS (zeige NRAS ELISA Kits) have an impact on biocatalysis (kinetics of GTP (zeige AK3 ELISA Kits) hydrolysis) and interaction with c-Raf (zeige RAF1 ELISA Kits) kinase, which must be due to allosteric effects on dynamics and conformational states, given the identical active sites of these isoenzymes.

  4. Data suggest HRas activates both p110alpha and p110delta isoforms; membrane-resident HRas, not soluble HRas, increases membrane recruitment of both p110alpha and p110delta. (HRas = v-Ha-ras Harvey rat sarcoma viral oncogene homolog; p110alpha = class IA phosphoinositide 3-kinases, subunit p110alpha; p110delta = class IA phosphoinositide 3-kinases, subunit p110delta)

  5. Our data suggest that testing for any RAS mutation is unlikely to change the clinical management of thyroid nodules that have indeterminate cytology

  6. Equilibrium dissociation constants were determined for the binding of HRAS, KRAS, NRAS and RRAS2 to the RAS binding (RB) domain of binding proteins.

  7. Studies indicate that RAS proteins were among the first oncogenes identified and are mutationally activated in 30% of all cancer types.

  8. 6 of 7 (86%) malignant ectomesenchymomas had HRAS mutations

  9. RAS-positive thyroid cancer most often demonstrates indolent sonographic features and more commonly associates with lower risk, "indeterminate" cytology.

  10. Studies indicate that the control of spatiotemporal RAS protein signalling show that activation kinetics and subcellular compartmentalisation are tightly coupled to the generation of specific biological outcomes.

Mouse (Murine) V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Interaktionspartner

  1. KrasG12D-driven proliferation of pancreatic ductal epithelial cells (PDECs) depends on an EGFR (zeige EGFR ELISA Kits) signaling loop engaging the oncogenic transcription factor c-MYC (zeige MYC ELISA Kits).

  2. median survival of KPIC mice was longer than that of LSL-KrasG12D; Ink4flox/flox; Ptf1/p48 (zeige PTF1A ELISA Kits)-Cre mice (KIC) (89 vs 62 days) and shorter than that of KRAS (KrasG12D), TP53 (zeige TP53 ELISA Kits) (Trp53R172H/+) and Ptf1/p48 (zeige PTF1A ELISA Kits)-Cre (KPC) mice

  3. Loss of N-cadherin in the context of oncogenic K-ras leads to increased pancreatic intraepithelial neoplasia (PanIN) incidence and progression.

  4. p21-associated inhibition of early-stage malignant progression and the intense expression in papilloma outgrowths, identifies a novel, significant antagonism between p21 and ras(Ha)/ROCK2 (zeige ROCK2 ELISA Kits)/NF-kappaB (zeige NFKB1 ELISA Kits) signalling in skin carcinogenesis.these data show that ROCK2 (zeige ROCK2 ELISA Kits) activation induces malignancy in ras(Ha)-initiated/promoted papillomas in the context of p53 (zeige TP53 ELISA Kits) loss and novel NF-kappaB (zeige NFKB1 ELISA Kits) expression

  5. activating mutations in GNAS and Kras cooperatively promote murine pancreatic tumorigenesis

  6. the Kras(mut (zeige MUT ELISA Kits)) allele was heterogenous in primary tumors yet homogenous in metastases, a pattern consistent with activated Kras(mut (zeige MUT ELISA Kits)) signaling being a driver of progression to metastasis.

  7. Using an extensive collection of novel murine cell lines we have identified distinct roles for Kras and Pten on MUC1 (zeige MUC1 ELISA Kits) and EMT (zeige ITK ELISA Kits) in vivo and in vitro. The data has implications for future design of combination therapies targeting Kras mutations, Pten deletions and MUC1 (zeige MUC1 ELISA Kits) vaccines.

  8. a potent tumor-suppressive function for Lfng (zeige LFNG ELISA Kits)

  9. pancreatic ductal cells, whereas exhibiting relative resistance to oncogenic Kras alone, can serve as an effective cell of origin for pancreatic ductal adenocarcinoma in the setting of gain-of-function mutations in p53 (zeige TP53 ELISA Kits)

  10. In vivo treatment of the KRAS(G12D)-induced Langerhans cell histiocytosis -like mouse with the cholesterol-lowering drug atorvastatin ameliorated the pathology, implicating statins as potential therapeutics against a subset of pulmonary Langerhans cell histiocytosis.

HRAS Antigen-Profil

Beschreibung des Gens

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

Alternative names and synonyms associated with HRAS

  • Harvey rat sarcoma viral oncogene homolog (hras) Elisa Kit
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS) Elisa Kit
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog a (hrasa) Elisa Kit
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) Elisa Kit
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) Elisa Kit
  • Harvey rat sarcoma viral oncogene homolog (HRAS) Elisa Kit
  • Harvey rat sarcoma virus oncogene (Hras) Elisa Kit
  • Harvey rat sarcoma virus oncogene 1 (Hras1) Elisa Kit
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog (Hras) Elisa Kit
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Kras) Elisa Kit
  • AI929937 Elisa Kit
  • C-BAS/HAS Elisa Kit
  • c-H-ras Elisa Kit
  • c-Ha-ras Elisa Kit
  • C-HA-RAS1 Elisa Kit
  • c-rasHa Elisa Kit
  • CTLO Elisa Kit
  • H-ras Elisa Kit
  • H-RASIDX Elisa Kit
  • Ha-ras Elisa Kit
  • HAMSV Elisa Kit
  • Harvey-ras Elisa Kit
  • hras Elisa Kit
  • Hras-1 Elisa Kit
  • HRAS1 Elisa Kit
  • K-ras Elisa Kit
  • Ki-ras Elisa Kit
  • Kras-2 Elisa Kit
  • Kras2 Elisa Kit
  • N-RAS Elisa Kit
  • p21B Elisa Kit
  • ras Elisa Kit
  • RASH1 Elisa Kit
  • zgc:110250 Elisa Kit

Bezeichner auf Proteinebene für HRAS

v-Ha-ras Harvey rat sarcoma viral oncogene homolog , small G-protein H-Ras , Harvey ras 1 , p19 H-RasIDX protein , GTPase HRas (Transforming protein p21) (H-Ras-1) (c-H-ras) , xRAS1 , GTPase HRas , Transforming protein p21 , neuroblastoma ras oncogene , GTP- and GDP-binding peptide B , H-Ras-1 , Ha-Ras1 proto-oncoprotein , Ras family small GTP binding protein H-Ras , c-has/bas p21 protein , c-ras-Ki-2 activated oncogene , p21ras , transformation gene: oncogene HAMSV , transforming protein p21 , Harvey ras1 protein , Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog , H-ras 1 protein , c-Ha-ras p21 protein , c-Ha-ras transgene , transforming protein P21 , GTPase NRas , transforming protein N-Ras , c-H-ras , v-Ha-ras Harvey rat sarcoma viral oncogene-like protein , ras p21 , GTPase KRas , K-Ras 2 , Kirsten rat sarcoma oncogene 2, expressed , c-K-ras , c-Ki-ras , p21 protein

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550286 Danio rerio
698830 Macaca mulatta
733587 Sus scrofa
100222058 Taeniopygia guttata
100227892 Taeniopygia guttata
3265 Homo sapiens
293621 Rattus norvegicus
15461 Mus musculus
100739349 Sus scrofa
100735038 Cavia porcellus
396229 Gallus gallus
403735 Canis lupus familiaris
100298939 Bos taurus
101104357 Ovis aries
16653 Mus musculus
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