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anti-GTPase NRas (NRAS) Antikörper

anti-GTPase NRas Antikörper (NRAS)
Auf finden Sie aktuell 99 GTPase NRas (NRAS) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GTPase NRas Proteine (17) und GTPase NRas Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 127 GTPase NRas Produkte verfügbar.
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1

Meistgesuchte Reaktivitäten zu anti-GTPase NRas (NRAS) Antikörper

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anti-Rat (Rattus) GTPase NRas Antikörper:

anti-Mouse (Murine) GTPase NRas Antikörper:

anti-Human GTPase NRas Antikörper:

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Am meisten referenzierte anti-GTPase NRas Antikörper

  1. Human Monoclonal GTPase NRas Primary Antibody für EIA, WB - ABIN781533 : Rocks, Peyker, Bastiaens: Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors. in Current opinion in cell biology 2006 (PubMed)
    Zeige alle 3 Referenzen für ABIN781533

  2. Human Polyclonal GTPase NRas Primary Antibody für EIA, IHC (p) - ABIN360039 : Smalley, Contractor, Nguyen, Xiao, Edwards, Muthusamy, King, Flaherty, Bosenberg, Herlyn, Nathanson: Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. in Cancer research 2008 (PubMed)
    Zeige alle 2 Referenzen für ABIN360039

  3. Human Polyclonal GTPase NRas Primary Antibody für EIA, FACS - ABIN360038 : Banerji, Affolter, Judson, Marais, Workman: BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors. in Molecular cancer therapeutics 2008 (PubMed)
    Zeige alle 2 Referenzen für ABIN360038

  4. Human Polyclonal GTPase NRas Primary Antibody für IHC (p), IHC - ABIN409077 : Thomas, Edmiston, Alexander, Millikan, Groben, Hao, Tolbert, Berwick, Busam, Begg, Mattingly, Ollila, Tse, Hummer, Lee-Taylor, Conway: Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007 (PubMed)

  5. Human Monoclonal GTPase NRas Primary Antibody für WB - ABIN1882272 : Hall, Brown: Human N-ras: cDNA cloning and gene structure. in Nucleic acids research 1985 (PubMed)

Weitere Antikörper gegen GTPase NRas Interaktionspartner

Mouse (Murine) GTPase NRas (NRAS) Interaktionspartner

  1. loss of one allele of Hras (zeige HRAS Antikörper) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (zeige HRAS Antikörper) allele. However, loss of one or both alleles of Nras failed to alter tumor burden, either in the absence or presence of Hras (zeige HRAS Antikörper), after exposure to urethane.

  2. Genetic inactivation of Ezh2 (zeige EZH2 Antikörper) or Eed (zeige EED Antikörper) cooperates with NRASQ61K in leukemogenesis.

  3. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  4. Activated NRAS and aberrant Wnt (zeige WNT2 Antikörper) signaling conspire to drive congenital melanocytic nevus syndrome.

  5. a crucial role of RXRa (zeige RXRA Antikörper) in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4 (zeige CDK4 Antikörper)(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 (zeige TP53 Antikörper) and PTEN (zeige PTEN Antikörper)

  6. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  7. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  8. NRAS expression is required for the proliferative advantage of human AML (zeige RUNX1 Antikörper) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (zeige RUNX1 Antikörper) in vivo

  9. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  10. Cbfbeta (zeige CBFB Antikörper)-SMMHC (zeige MYH11 Antikörper) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (zeige MDK Antikörper)/ERK (zeige EPHB2 Antikörper)/Bim (zeige BCL2L11 Antikörper) axis, and define Nras(LSL-G12D); Cbfb (zeige CBFB Antikörper)(56M) mice as a valuable genetic model for the study of AML (zeige RUNX1 Antikörper) therapies.

Human GTPase NRas (NRAS) Interaktionspartner

  1. The data revealed the presence of a partial tandem duplication of the MLL (zeige MLL Antikörper) gene as the only detectable copy number change and 11 non-silent somatic mutations, including DNMT3A (zeige DNMT3A Antikörper) R882H and NRAS G13D. All somatic lesions were present both at initial MDS (zeige PAFAH1B1 Antikörper)/MPN (zeige PRSS27 Antikörper)-U diagnosis and at AML (zeige RUNX1 Antikörper) presentation at similar mutant allele frequencies.

  2. NRAS mutation is associated with CNS melanoma.

  3. NRAS mutation is associated with melanoma.

  4. Silencing VPS35 (zeige vps35 Antikörper) increased N-Ras's association with cytoplasmic vesicles, diminished GTP (zeige AK3 Antikörper) loading of Ras, and inhibited mitogen-activated protein kinase (zeige MAPK1 Antikörper) signaling and growth of N-Ras-dependent melanoma cells.

  5. By using this model of curative-intent, margin-negative resection in patients at high risk of recurrence, the authors were able to establish a link between mutation location within the K/NRAS gene and the biology of metastatic colorectal cancer.

  6. review focuses on the genes, which are frequently mutated in various cancers and are known to be important in the advance and progression of colorectal cancer and melanoma, namely KRAS, NRAS and BRAF (zeige BRAF Antikörper)

  7. Report KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer may depend on tumor histology.

  8. SP174 immunohistochemistry allows sensitive detection of NRAS and KRAS Q61R mutants.

  9. multiregion analysis was performed in 60 spatially separated tumor areas according to the pathological tumor node metastasis (pTNM) staging and KRAS, NRAS and BRAF mutations were tested using pyrosequencing.these results suggest the need for multiple RAS testing in different parts of the same tumor and/or more sensitive techniques.

  10. that the presence of NRAS, PTEN (zeige PTEN Antikörper) and AKT1 (zeige AKT1 Antikörper) gene mutations may have an influence on the occurrence of CNS metastases in patients with SqCC

Zebrafish GTPase NRas (NRAS) Interaktionspartner

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (zeige TP53 Antikörper) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) Antigen-Profil

Beschreibung des Gens

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117) Antikörper
  • African clawed frog N-ras (n-ras) Antikörper
  • neuroblastoma ras oncogene (Nras) Antikörper
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) Antikörper
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras) Antikörper
  • ALPS4 Antikörper
  • AV095280 Antikörper
  • fj99a10 Antikörper
  • H-RAS Antikörper
  • HRAS Antikörper
  • N-RAS Antikörper
  • NRAS Antikörper
  • NRAS1 Antikörper
  • NS6 Antikörper
  • wu:fj99a10 Antikörper
  • zgc:100761 Antikörper
  • zras-b1 Antikörper

Bezeichner auf Proteinebene für anti-GTPase NRas (NRAS) Antikörper

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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