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anti-GTPase NRas (NRAS) Antikörper

Bezeichnung:
anti-GTPase NRas Antikörper (NRAS)
Auf www.antikoerper-online.de finden Sie aktuell 102 GTPase NRas (NRAS) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GTPase NRas Proteine (18) und GTPase NRas Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 131 GTPase NRas Produkte verfügbar.
Synonyme:
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1

Meistgesuchte Reaktivitäten zu anti-GTPase NRas (NRAS) Antikörper

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anti-Rat (Rattus) GTPase NRas Antikörper:

anti-Mouse (Murine) GTPase NRas Antikörper:

anti-Human GTPase NRas Antikörper:

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Am meisten referenzierte anti-GTPase NRas Antikörper

  1. Human Monoclonal GTPase NRas Primary Antibody für EIA, WB - ABIN781533 : Rocks, Peyker, Bastiaens: Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors. in Current opinion in cell biology 2006 (PubMed)
    Zeige alle 3 Referenzen für ABIN781533

  2. Human Polyclonal GTPase NRas Primary Antibody für EIA, IHC (p) - ABIN360039 : Smalley, Contractor, Nguyen, Xiao, Edwards, Muthusamy, King, Flaherty, Bosenberg, Herlyn, Nathanson: Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. in Cancer research 2008 (PubMed)
    Zeige alle 2 Referenzen für ABIN360039

  3. Human Polyclonal GTPase NRas Primary Antibody für EIA, FACS - ABIN360038 : Banerji, Affolter, Judson, Marais, Workman: BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors. in Molecular cancer therapeutics 2008 (PubMed)
    Zeige alle 2 Referenzen für ABIN360038

  4. Human Polyclonal GTPase NRas Primary Antibody für IHC (p), IHC - ABIN409077 : Thomas, Edmiston, Alexander, Millikan, Groben, Hao, Tolbert, Berwick, Busam, Begg, Mattingly, Ollila, Tse, Hummer, Lee-Taylor, Conway: Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007 (PubMed)

  5. Human Monoclonal GTPase NRas Primary Antibody für WB - ABIN1882272 : Hall, Brown: Human N-ras: cDNA cloning and gene structure. in Nucleic acids research 1985 (PubMed)

Weitere Antikörper gegen GTPase NRas Interaktionspartner

Mouse (Murine) GTPase NRas (NRAS) Interaktionspartner

  1. Genetic inactivation of Ezh2 (zeige EZH2 Antikörper) or Eed (zeige EED Antikörper) cooperates with NRASQ61K in leukemogenesis.

  2. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  3. Activated NRAS and aberrant Wnt (zeige WNT2 Antikörper) signaling conspire to drive congenital melanocytic nevus syndrome.

  4. a crucial role of RXRa (zeige RXRA Antikörper) in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4 (zeige CDK4 Antikörper)(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 (zeige TP53 Antikörper) and PTEN (zeige PTEN Antikörper)

  5. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  6. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  7. NRAS expression is required for the proliferative advantage of human AML (zeige RUNX1 Antikörper) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (zeige RUNX1 Antikörper) in vivo

  8. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  9. Cbfbeta (zeige CBFB Antikörper)-SMMHC (zeige MYH11 Antikörper) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (zeige MDK Antikörper)/ERK (zeige EPHB2 Antikörper)/Bim (zeige BCL2L11 Antikörper) axis, and define Nras(LSL-G12D); Cbfb (zeige CBFB Antikörper)(56M) mice as a valuable genetic model for the study of AML (zeige RUNX1 Antikörper) therapies.

  10. regulation of Nf1 exon 23a inclusion serves as a mechanism for providing appropriate levels of Ras signaling.

Human GTPase NRas (NRAS) Interaktionspartner

  1. NRAS mutation is associated with metastatic melanoma.

  2. The BRAF (zeige BRAF Antikörper) was mutated in 55% (29/53) and NRAS in 11% (5/45) of the primary melanomas sequenced.

  3. Her-2 (zeige ERBB2 Antikörper), N-ras and Nf1 (zeige NF1 Antikörper) have roles in brain onocogenesis

  4. High NRAS expression is associated with hepatocellular carcinoma.

  5. Rare mutations in KRAS, NRAS, and BRAF (zeige BRAF Antikörper) oncogenes have been found in patients with melanoma and colorectal neoplasms.

  6. NRAS and BRAF (zeige BRAF Antikörper) mutations are independent events and alternative molecular mechanisms in the primary oral mucosal melanoma tumorigenesis

  7. NRAS gene mutations are associated with Urinary Bladder Cancer.

  8. Driver mutations are rare in mutational hotspots of BRAF (zeige BRAF Antikörper), NRAS, KIT, and GNAQ (zeige GNAQ Antikörper)/GNA11 (zeige GNA11 Antikörper) in oral mucosal melanoma.

  9. NRAS mutation was more often seen in patients with lymph node metastasis. As BRAF (zeige BRAF Antikörper) and NRAS mutations are rare in Taiwan, BRAF (zeige BRAF Antikörper)- or NRAS-targeted therapies may be effective only for selected Taiwanese melanoma patients.

  10. Results shows the structural characterization of NRAS isoform 5 which overexpression results in more aggressive phenotype of melanoma. The protein was found highly flexible in aqueous solution, but forms a helix-turn-coil structure in the presence of trifluoroethanol.

Zebrafish GTPase NRas (NRAS) Interaktionspartner

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (zeige TP53 Antikörper) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) Antigen-Profil

Beschreibung des Gens

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117) Antikörper
  • African clawed frog N-ras (n-ras) Antikörper
  • neuroblastoma ras oncogene (Nras) Antikörper
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) Antikörper
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras) Antikörper
  • ALPS4 Antikörper
  • AV095280 Antikörper
  • fj99a10 Antikörper
  • H-RAS Antikörper
  • HRAS Antikörper
  • N-RAS Antikörper
  • NRAS Antikörper
  • NRAS1 Antikörper
  • NS6 Antikörper
  • wu:fj99a10 Antikörper
  • zgc:100761 Antikörper
  • zras-b1 Antikörper

Bezeichner auf Proteinebene für anti-GTPase NRas (NRAS) Antikörper

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

GENE ID SPEZIES
10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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