Retinoid X Receptor alpha Proteine (RXRA)

Retinoid X Receptor, alpha Proteine (RXRA)
Auf finden Sie aktuell 12 Retinoid X Receptor, alpha (RXRA) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Retinoid X Receptor alpha Antikörper (88) und Retinoid X Receptor alpha Kits (17) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 135 Retinoid X Receptor alpha Produkte verfügbar.
9530071D11Rik, etID309733.19, NR2B1, NR2B2-A, RXR, RXRA, rxra-A, RXRalpha, RXR alpha, RXRalpha1, rxrb, rxre, wu:fb93c09, xrxra, xRXR alpha
alle Proteine anzeigen Gen GeneID UniProt
RXRA 20181 P28700
RXRA 25271  
RXRA 6256 P19793

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Weitere Proteine zu Retinoid X Receptor alpha Interaktionspartnern

Mouse (Murine) Retinoid X Receptor, alpha (RXRA) Interaktionspartner

  1. These results suggest a mechanism to establish RXR therapeutic targets with significance in neurodegeneration.

  2. The optimal PPARalpha (zeige PPARA Proteine)/RXRalpha heterodimer binding sequence was WAWVTRGGBBAHRGKTYA. The single nucleotide substitution, which reduces binding of RXRalpha to DNA, attenuated PPARalpha (zeige PPARA Proteine)-induced transcriptional activation, but this is not always true for PPARalpha (zeige PPARA Proteine).

  3. A change in the heterodimeric partner of Peroxisome Proliferator Activated Receptor-alpha (zeige PPARA Proteine) from retinoid X receptor (zeige RXRB Proteine) to Silent information regulator 1 is responsible for the impaired fatty acid metabolism and cardiac dysfunction in the failing heart.

  4. interaction of Wnt and RXR-alpha pathways in hepatocyte development and hepatocellular carcinoma

  5. a crucial role of RXRa in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 and PTEN

  6. This uncovered a novel RXR-dependent innate immune regulatory pathway, suggesting that downregulation of RXR expression or RXR antagonist treatment benefits host antiviral response, whereas RXR agonist treatment may increase risk of viral infections.

  7. Data suggest that retinoic acid and GM-CSF (zeige CSF2 Proteine)-induced retinal dehydrogenase 2 (RALDH2 (zeige ALDH1A2 Proteine)) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (zeige SP1 Proteine) via the RA receptor/retinoid X receptor (zeige RXRB Proteine) complex to the Aldh1a2 (zeige ALDH1A1 Proteine) promoter.

  8. The expression and binding of RXRalpha to CYP3A genes in liver was sex-dependent and regulated by growth hormone (zeige GH1 Proteine) secretion.

  9. The depletion of retinoic acid and the inhibition of RXRalpha function in hepatic tumors involve more complex mechanisms besides the activation of RAS/ERK (zeige EPHB2 Proteine) pathway.

  10. These observations suggest that beta-apo (zeige C9orf3 Proteine)-13-carotenone regulates RXRalpha transcriptional activity by inducing the formation of the "transcriptionally silent" RXRalpha tetramer.

Human Retinoid X Receptor, alpha (RXRA) Interaktionspartner

  1. Data suggest that the binding of Z-10 to RXRalpha inhibited the interaction of RXRalpha with PML (zeige PML Proteine)-RARalpha (zeige RARA Proteine), leading to Z-10's selective induction of PML (zeige PML Proteine)-RARalpha (zeige RARA Proteine) degradation.

  2. This suggests that hRXRalpha phosphorylation significantly disrupts its nuclear localization, interaction with VDR (zeige CYP27B1 Proteine), intra-nuclear trafficking, and binding to chromatin of the hVDR-hRXR complex.

  3. the expression of CAMP, vitamin D receptor (VDR), and the retinoid X receptor (RXR) isoforms in human skin and gingival tissue biopsies and investigated the signaling pathways involved in 1alpha,25-dihydroxyvitamin D3-induced upregulation of CAMP.

  4. data show that RXRalpha expression is increased in miscarriage in endometrial glands and correlation analysis showed that negative correlation between RXRalpha and PPARgamma (zeige PPARG Proteine) disappears in miscarriage. This shift is supposable responsible for the loss of regular function in trophoblast and embryonic tissue.

  5. IL-1beta (zeige IL1B Proteine) upregulated RXRalpha through activation of NF-kappaB (zeige NFKB1 Proteine) signaling.

  6. RXRA rs10776909 allele T is specifically involved in the pathogenesis of ChGN (zeige CSGALNACT1 Proteine). This risk allele may be also associated with worse clinical course of ChGN (zeige CSGALNACT1 Proteine).

  7. Results suggest that retinoid X receptor (zeige RXRB Proteine) (RXR) activation protects retinal pigment epithelium (RPE (zeige RPE Proteine)) cells from oxidative stress-induced (zeige SQSTM1 Proteine) apoptosis.

  8. Data show that pregnane X receptor/retinoid X receptor PXR/RXR-[alpha], RXR-[beta], or RXR-[gamma] expression was noted in 9 (16.4%), 9 (16.4%), and 10 (18.2%) pancreatic adenocarcinoma cases, respectively.

  9. Retinoid X receptor alpha plays an important role in proliferation of cholangiocarcinoma

  10. Data suggest a potential therapeutic role for the low toxicity synthetic retinoid X receptor (zeige RXRB Proteine) selective agonist, UAB30, in neuroblastoma (zeige ARHGEF16 Proteine) treatment.

Pig (Porcine) Retinoid X Receptor, alpha (RXRA) Interaktionspartner

  1. Expression of TauT is differentially regulated by Vitamin D(3) and retinoic acid via formation of VDR and RXR complexes in the nuclei in a cell type-dependent manner.

Retinoid X Receptor alpha (RXRA) Protein Überblick

Protein Überblick

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.

Alternative names and synonyms associated with Retinoid X Receptor alpha (RXRA)

  • retinoid X receptor, alpha (RXRA)
  • retinoid X receptor alpha (CpipJ_CPIJ010249)
  • retinoid X receptor alpha (Rxra)
  • retinoid X receptor, alpha (rxra)
  • retinoid x receptor, beta a (rxrba)
  • 9530071D11Rik Protein
  • etID309733.19 Protein
  • NR2B1 Protein
  • NR2B2-A Protein
  • RXR Protein
  • RXRA Protein
  • rxra-A Protein
  • RXRalpha Protein
  • RXR alpha Protein
  • RXRalpha1 Protein
  • rxrb Protein
  • rxre Protein
  • wu:fb93c09 Protein
  • xrxra Protein
  • xRXR alpha Protein

Bezeichner auf Proteinebene für RXRA

retinoid X receptor, alpha , retinoid X receptor alpha , RXR alpha 1 , nuclear receptor subfamily 2 group B member 1 , retinoic acid receptor RXR-alpha , retinoid X nuclear receptor alpha , retinoic acid receptor , retinoid x receptor alpha , retinoid X receptor alpha protein , fb93c09 , nuclear receptor subfamily 2 group B member 2-A , retinoic acid receptor RXR-beta-A , retinoid X receptor beta-A , retinoid receptor-epsilon , retinoid x receptor, epsilon

417143 Gallus gallus
464834 Pan troglodytes
722068 Macaca mulatta
6042610 Culex quinquefasciatus
20181 Mus musculus
25271 Rattus norvegicus
6256 Homo sapiens
491278 Canis lupus familiaris
378685 Xenopus laevis
397306 Sus scrofa
507554 Bos taurus
30530 Danio rerio
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